Guest of the League
| Away | Home | Time | Away Probable | Home Probable | Status | |||
|---|---|---|---|---|---|---|---|---|
 | Royals | at |  | Guardians | 1:10pm ET | Cameron (1-0) | Williams R (1-1) | |
 | Orioles | at |  | White Sox | 3:10pm ET | Rogers L (2-0) | Smith R (0-2) | |
 | Diamondbacks | at |  | Mets | 4:10pm ET | Gallen R (1-1) | Peralta R (1-0) | |
 | Cubs | at |  | Rays | 6:40pm ET | Assad R (0-0) | Englert R (0-0) | |
 | Reds | at |  | Marlins | 6:40pm ET | Abbott L (0-1) | Alcantara R (2-0) | |
 | Padres | at |  | Pirates | 6:40pm ET | Pivetta R (1-1) | Skenes R (1-1) | |
 | Cardinals | at |  | Nationals | 6:45pm ET | Liberatore L (0-0) | Cavalli R (0-0) | |
 | Brewers | at |  | Red Sox | 6:45pm ET | Misiorowski R (1-0) | Crochet L (1-1) | |
 | Athletics | at |  | Yankees | 7:05pm ET | Civale R (1-0) | Schlittler R (2-0) | 7:05pm |
 | Dodgers | at |  | Blue Jays | 7:07pm ET | Yamamoto R (1-1) | Gausman R (0-0) | |
 | Tigers | at |  | Twins | 7:40pm ET | Skubal L (1-1) | Bradley R (1-0) | 7:40pm |
 | Mariners | at |  | Rangers | 8:05pm ET | Kirby R (1-1) | Eovaldi R (0-2) | 8:05pm |
 | Astros | at |  | Rockies | 8:40pm ET | Burrows R (1-1) | Freeland L (0-1) | 8:40pm |
 | Braves | at |  | Angels | 9:38pm ET | Lopez R (1-0) | Kikuchi L (0-1) | 9:38pm |
 | Phillies | at |  | Giants | 9:45pm ET | Sanchez L (1-0) | Ray L (1-1) | 9:45pm |
