Guest of the League
| Away | Home | Time | Away Probable | Home Probable | Status | |||
|---|---|---|---|---|---|---|---|---|
 | Cubs | at |  | Guardians | 1:10pm ET | Cabrera R (1-0) | Cecconi R (0-1) | |
 | Dodgers | at |  | Nationals | 1:35pm ET | Sasaki R (0-1) | Griffin L (1-0) | |
 | Marlins | at |  | Yankees | 1:35pm ET | Paddack R (0-1) | Fried L (2-0) | |
 | Padres | at |  | Red Sox | 1:35pm ET | Buehler R (0-1) | Suarez L (0-1) | |
 | Orioles | at |  | Pirates | 1:35pm ET | Bassitt R (0-2) | Ashcraft (1-1) | |
 | Brewers | at |  | Royals | 2:10pm ET | Harrison L (0-0) | Bubic L (1-0) | |
 | Rays | at |  | Twins | 2:10pm ET | Martinez R (0-0) | Woods Richardson R (0-1) | |
 | Blue Jays | at |  | White Sox | 2:10pm ET | Lauer L (1-0) | Martin R (1-0) | |
 | Reds | at |  | Rangers | 2:35pm ET | Burns R (1-0) | Leiter R (1-0) | |
 | Phillies | at |  | Rockies | 3:10pm ET | Walker R (0-1) | Sugano R (0-0) | |
 | Astros | at |  | Athletics | 4:05pm ET | McCullers Jr. R (1-0) | Lopez L (0-1) | |
 | Mets | at |  | Giants | 4:05pm ET | Senga R (0-1) | Webb R (1-1) | |
 | Mariners | at |  | Angels | 4:07pm ET | Castillo R (0-0) | Klassen R (0-0) | |
 | Braves | at |  | Diamondbacks | 4:10pm ET | Perez L (0-0) | Pfaadt R (0-0) | |
| Cubs | at | | Guardians | 4:40pm ET | Imanaga L (0-1) | Messick L (1-0) | 4:40pm |
 | Cardinals | at |  | Tigers | 7:20pm ET | Leahy R (0-1) | Montero R (0-0) | 7:20pm |
