The Tampa Bay Buccaneers have updated their injury report, and All-Pro receiver Mike Evans (hamstring) is one of only two players to be officially ruled out of Sunday's Week 4 matchup with the Eagles. This comes as no surprise, as Evans is expected to miss multiple weeks after an MRI on Tuesday revealed a mild to moderate strain of his left hamstring. Evans missed three games last season with an injury to his right hamstring and has a history of soft tissue issues. While Chris Godwin (ankle) is currently listed as questionable, it would be a surprise to see him handle a full allotment of snaps in his first game back from the devastating ankle injury that ended his 2024 season. Rookie Emeka Egbuka is in line to pace the team in targets against the defending champs and is a must-start this week.

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Buffalo Bills slot receiver Khalil Shakir found the end zone for the first time this season in a win over the Miami Dolphins in Week 3. Shakir also hauled in all four passes thrown his way for 45 yards, though it's alarming for fantasy managers that he combined for just six targets over the past two games. He averaged a little under seven per contest during a career year last season. While it's still early, Shakir is nowhere near his 2024 pace in catches, targets, or yards. He's now heading into a Week 4 matchup against a New Orleans defense that has given up the 11th-most fantasy points to receivers this year. The Saints had difficulty slowing down the Seattle Seahawks' top WR, Jaxon Smith-Njigba, in a blowout loss last week, as he tallied five catches for 96 yards and a touchdown. Shakir has never been a major TD threat, however, which makes it imperative for his targets to increase to 2024 levels if he's going to pay dividends for fantasy managers. Until that happens, it's tough to rely on Shakir, who's going into Sunday as RotoBaller's 40th-ranked WR.

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New England Patriots head coach Mike Vrabel said there won't be any playing-time discipline for running back Rhamondre Stevenson, whose ball-security issues resurfaced in last week's loss to the Pittsburgh Steelers when he lost two crucial fumbles. "We need our best players to play in the game and do their jobs and take care of the football," Vrabel said. The 27-year-old only had four carries for 18 yards and caught all three of his targets for 38 yards in the Week 3 loss. Many people assumed he'd be in Vrabel's doghouse after coughing the ball up twice, but that doesn't appear to be the case. Stevenson's big Week 2 performance might have bought him some slack, but it could only be a matter of time before rookie TreVeyon Henderson gets his shot. Consider Stevenson a shaky RB3/flex play in fantasy this week. One more gaffe could be the end of his chances at the RB1 role in New England.

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Buffalo Bills running back James Cook, coming off his second straight game with 100-plus yards rushing, has a chance to keep rolling against the winless New Orleans Saints in Week 4. Although the Saints rank a respectable 14th in rushing yards allowed (103.3 per game), they've given up the seventh-most fantasy points to RBs through three weeks. That bodes well for Cook, who ranks second at his position in fantasy points and has encouragingly carried over his 2024 touchdown prowess into this season. After scoring 16 times on the ground a year ago, Cook has already found pay dirt four times in 2025 as the second-biggest weapon (behind quarterback Josh Allen) on an elite offense.

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Las Vegas Raiders quarterback Geno Smith enters Week 4 with a strong opportunity to post QB1 numbers against the struggling Chicago Bears defense. Chicago has allowed 247.7 passing yards per game while ranking 27th in total defense and 26th against the pass, creating an inviting matchup for fantasy managers. Smith is coming off a sharp performance in Week 3 where he threw for 289 yards and three touchdowns, showing clear chemistry with his receiving corps. With the Bears' secondary routinely giving up big plays, Smith carries both a safe floor and a sneaky-high ceiling this week. He should be started confidently as a low-end QB1 in all fantasy formats.

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After bouncing back in Week 3 against the Miami Dolphins, Buffalo Bills quarterback Josh Allen is set up for success going into Sunday's home matchup versus the 0-3 New Orleans Saints. The reigning MVP will face a defense that has surrendered the seventh-most fantasy points to quarterbacks, even though the Saints haven't gone up against anyone in Allen's stratosphere. They've instead struggled against lesser signal-callers in Kyler Murray, Mac Jones, and Sam Darnold. Those three combined to complete 70.8 percent of passes with seven touchdown tosses, zero interceptions, and a lofty 118.9 QB rating. While Jones and Darnold don't scare anyone with their legs, the mobile Murray scampered for 38 yards on seven rushes against New Orleans. That's good news for Allen, an elite dual threat fantasy managers can confidently count on going into Week 4.

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Indianapolis Colts head coach Shane Steichen has ruled out wide receiver Alec Pierce (concussion) from the Week 4 contest this Sunday against the Los Angeles Rams, according to Mike Chappell of FOX 59. Things were trending this way after Pierce missed all three practices this week. The 25-year-old will look to clear the league's concussion protocol next before a Week 5 home matchup against the Las Vegas Raiders. With Pierce sidelined this weekend, quarterback Daniel Jones will be forced to lean more on receivers Michael Pittman Jr., Josh Downs, and Adonai Mitchell. Impressive rookie tight end Tyler Warren will also have a higher ceiling as the Colts look to stay undefeated in a tough matchup against the Rams' defense. Pierce has been a pretty steady target of Jones through three games, catching nine of 13 targets for 171 yards, but he has yet to score.

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The Pittsburgh Steelers added running back Jaylen Warren (knee) to the Week 4 injury report, and he's now questionable to play on Sunday versus the Minnesota Vikings in Dublin, Ireland, according to Tom Pelissero of NFL Network. Warren was on the injury report this week and was listed with a knee, but also as veteran rest when he was limited in Thursday's practice. The 26-year-old's status is obviously worth keeping an eye on going into Sunday's international game, but we'd be surprised if he were ruled inactive. But if he doesn't play, Kenneth Gainwell would be a popular waiver-wire pickup and flex plug-and-play this weekend. Rookie Kaleb Johnson, who was a healthy scratch last week, would likely be active as a change-of-pace option alongside Trey Sermon. Warren has been very productive through three weeks and is a must-start RB if he plays.

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Washington Commanders head coach Dan Quinn said on Friday that the depth wide receivers on the roster are ready for the moment in Week 4 against the Atlanta Falcons, with top wideout Terry McLaurin (quadriceps) being ruled out, according to Zach Selby of Commanders.com. At the top of that list is second-year pass-catcher Luke McCaffrey, who caught all three of his targets for 56 yards and his first career touchdown in the Week 3 win over the Las Vegas Raiders after McLaurin was injured. In addition to McCaffrey, rookie Jaylin Lane and Chris Moore will have additional opportunities in the passing game this weekend with McLaurin ruled out. McLaurin's absence could extend into Week 5, too, so McCaffrey and Lane are worth a look on the waiver wire in deeper leagues. Limiting McCaffrey's streaming appeal in Week 4 is the fact that quarterback Jayden Daniels (knee) will miss a second straight game.

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Pittsburgh Steelers TE Jonnu Smith (hip) was limited during practice Friday, Sept. 26, and is listed as questionable for Week 4.

Fantasy Spin: Fantasy players can check the inactive list to see if Smith will be available for Week 4. He has been a short yardage option in the passing game but has seen a decent amount of targets in each game. He probably can be avoided in most leagues even if he is active.

From TheHuddle

Carolina Panthers running back Chuba Hubbard (calf) is listed as questionable to play on Sunday in the Week 4 game against the New England Patriots due to a calf injury, according to Adam Schefter of ESPN. Hubbard didn't pop up on this week's injury report until Thursday and was listed as a limited participant. He was limited again on Friday and was seen with a sleeve on his leg. The 26-year-old is probably on the right side of questionable for this weekend, but fantasy managers are going to need to check on Sunday morning to see if he's active for Carolina. Even if Hubbard plays, he could be susceptible to losing valuable backfield touches to backup Rico Dowdle against a Patriots defense that has been strong against the run through three games. If Hubbard is ruled out entirely, it will bump Dowdle up to flex territory in fantasy for those in need at the RB position.

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Carolina Panthers wide receiver Xavier Legette (hamstring) has officially been ruled out for the Week 4 road tilt against the New England Patriots on Sunday, according to ESPN's Adam Schefter. It will be the second straight game that Legette will miss after he was unable to practice at all this week. He will need to get back on the practice field next week if he wants to return for a Week 5 matchup against the Miami Dolphins. Rookie first-rounder Tetairoa McMillan (calf) is also questionable this weekend, so the Panthers could be pretty thin at wideout. Tight end Ja'Tavion Sanders (ankle) will also miss multiple weeks with a high-ankle sprain. It's setting up nicely for New England's defense in this one. With Legette out, Hunter Renfrow, David Moore, and Brycen Tremayne will battle for additional snaps and targets. Renfrow would be worth a look as a sleeper, but probably only if McMillan is out as well.

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Washington Commanders quarterback Jayden Daniels (knee) has officially been ruled out for Sunday's Week 4 game against the Atlanta Falcons, according to Ian Rapoport of NFL Network. Daniels will miss a second straight game due to a knee sprain that he suffered in Week 2. The good news is that Daniels made progress this week and put in a few limited practices, which will give him a much better chance to make his return in a Week 5 date against the Los Angeles Chargers. Washington will also be without star wideout Terry McLaurin (quadriceps) this weekend, forcing Deebo Samuel Sr., Luke McCaffrey, and rookie Jaylin Lane in starting three-wide sets against the Falcons. Veteran Marcus Mariota looked good in his first start of the year in last week's win over the Las Vegas Raiders, and he'll once again be in play as a QB2 streamer in superflex leagues.

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Washington Commanders head coach Dan Quinn is calling wide receiver Terry McLaurin (quadriceps) "week-to-week," and he's officially been ruled out for the Week 4 contest against the Atlanta Falcons on Sunday, according to NFL Network's Mike Garafolo. McLaurin did not practice all week and sought multiple medical opinions, including from a core-muscle specialist. Surgery has been ruled out for now, but it's looking like the 30-year-old could be facing a multi-week absence. Fantasy managers should consider him very up in the air to return for a Week 5 tilt against the Los Angeles Chargers. The Commanders will also be without quarterback Jayden Daniels (knee) for the second straight week, so they will be missing two of their best players this weekend against Atlanta. With McLaurin out, Luke McCaffrey and rookie Jaylin Lane will see an increase in snaps and targets behind Deebo Samuel Sr.

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Indianapolis Colts wide receiver Alec Pierce (concussion) is missing practice for a third straight day this week on Friday, according to James Boyd of The Athletic. Pierce suffered a concussion in the Week 3 win over the Tennessee Titans and appears unlikely to suit up this weekend against the Los Angeles Rams on Sunday. The 25-year-old will most likely be ruled out here soon on Friday. He's seen his involvement tick up the last two weeks after a slow one-catch season opener, and Pierce has nine grabs on 13 targets for 171 yards through the first three weeks. However, fantasy managers in deeper leagues will need to move him to their benches in Week 4. With Pierce not expected to play on Sunday, it will mean more targets for receivers Michael Pittman Jr., Josh Downs, and Adonai Mitchell, and rookie tight end Tyler Warren.

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Tampa Bay Buccaneers head coach Todd Bowles said that wide receiver Chris Godwin (ankle) will be listed as questionable for Sunday's Week 4 game against the Philadelphia Eagles, according to Greg Auman of FOX Sports. Despite the questionable tag, Godwin is still trending in the right direction to make his 2025 debut after suffering an ugly ankle dislocation in Week 7 of last year. It's good timing with fellow wideout Mike Evans (hamstring) set to miss at least a couple of weeks with a hamstring injury he suffered in Week 3. The 29-year-old Godwin will be a big part of Tampa's passing attack this year, but it might take him a bit to get up to speed after such a long layoff from game action. Expect the Bucs to ease him back into the offense this weekend if he's officially active, with rookie Emeka Egbuka and Sterling Shepard likely seeing more targets.

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Tampa Bay Buccaneers quarterback Baker Mayfield (biceps) resumed throwing the football before practice on Friday, according to Rick Stroud of the Tampa Bay Times. Mayfield has been limited in practice this week with a biceps injury in his right arm. The 30-year-old veteran is one of the toughest players in the league and is expected to be active in a Week 4 showdown against the Philadelphia Eagles, but it's fair to wonder if he'll be limited in what he can do down the field on Sunday. He was seen wearing a sleeve on his right throwing arm on Thursday. In addition to potentially not being 100 percent this weekend, Mayfield will be without top receiver Mike Evans, who is expected to miss multiple weeks with a hamstring injury he suffered in Week 3. In a less-than-ideal matchup against Philly, Mayfield should be viewed as a shaky QB streamer this week in fantasy.

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Cleveland Browns running backs coach Duce Staley said that rookie RB Dylan Sampson will get more playing time as the season goes on and they'll have a 1-2-3 punch with fellow rookie Quinshon Judkins and Jerome Ford, according to Scott Petrak. Sampson began the 2025 season splitting the backfield workload with Ford while Judkins dealt with an off-the-field issue. He had 12 carries for 29 yards and also caught all eight of his targets for an extra 64 yards in the season-opening loss to the Cincinnati Bengals, but in the two games since Judkins has returned, Sampson has just five combined carries for eight yards and has caught three passes for 13 yards. The 21-year-old is apparently going to be more involved as the season progresses, but his weekly fantasy ceiling and floor will remain low as long as Judkins dominates Cleveland's backfield work.

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Washington Commanders rookie running back Jacory Croskey-Merritt (knee) is on the practice field on Friday, according to John Keim of ESPN. However, Croskey-Merritt wasn't doing much with the team doing special teams work in the period of practice open to the media. The 24-year-old did not practice on Wednesday or Thursday due to a sore knee, so his status is definitely worth watching as Sunday's Week 4 game against the Atlanta Falcons approaches. It's a good sign that JCM was on the field on Friday, but it doesn't guarantee that he'll be active this weekend. If Croskey-Merritt can suit up in Week 4, he'll be an RB3/flex option, at best, in a backfield that remains a committee after the season-ending injury to Austin Ekeler (Achilles) in Week 2. If JCM doesn't get the green light this weekend, both Chris Rodriguez Jr. and Jeremy McNichols would jump onto the flex radar against Atlanta.

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Cleveland Browns running backs coach Duce Staley said that rookie RB Quinshon Judkins got the foundation of the offense during spring workouts and that it's "showing up now" despite his late arrival due to off-the-field issues this summer during training camp and the preseason, according to Scott Petrak. Judkins didn't make his NFL debut until Week 2, but he saw 10 carries in the loss to the Baltimore Ravens, rushing for 61 yards (6.1 yards per carry). The 21-year-old from Ohio State looked good again in last week's upset win over the Green Bay Packers and had an expanded role, rushing for 94 yards and his first career touchdown on 18 rushing attempts. The second-rounder is already Cleveland's clear RB1 ahead of Jerome Ford and fellow rookie Dylan Sampson, and his big-play ability makes him a must-start in all fantasy leagues, even in a low-scoring Browns offense.

From RotoBaller