Indianapolis Colts wide receiver Michael Pittman Jr. (glute) was able to practice in full on Thursday and Friday and has been cleared to play in Week 10 against the Atlanta Falcons in Berlin, Germany, on Sunday. Pittman was held out of Wednesday's practice with a glute injury, but he quickly returned to a full practice on Thursday and is fine to play overseas this weekend. The 28-year-old needs to be in all starting fantasy lineups this weekend as the Colts look to bounce back from only their second loss of the year last week to the Pittsburgh Steelers. Pittman has been the clear WR1 for the Colts and quarterback Daniel Jones in 2025, catching 52 of his 68 targets for 561 yards and six touchdowns in what has been a fine bounce-back season for him. He could be primed for another big game against Atlanta, a defense that has been more vulnerable to WRs in recent weeks.

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Los Angeles Chargers running back Kimani Vidal struggled against the Tennessee Titans' weak run defense, gaining only 30 yards on 12 carries, averaging just 2.5 yards per carry. This Week 10 matchup against the Pittsburgh Steelers presents a much tougher challenge, as the Steelers just held the league's top running back, Jonathan Taylor, to a season-low 45 yards. The Steelers have significantly improved their run defense since the first half of the season, making Vidal's chances of fantasy success highly dependent on a positive game script. With Hassan Haskins (hamstring) and Omarion Hampton (ankle) still on IR, Vidal will see the volume, but if the game stays close, a pass-heavy approach could limit his rushing opportunities. Vidal is considered a mid-range RB2 and a high-floor PPR FLEX option, projected as RB17. However, his ceiling depends on the Chargers securing an early lead.

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Kicker Will Reichard should be considered an average fantasy option when his Minnesota Vikings play host to the Baltimore Ravens in Week 10. Baltimore ranks 24th against fantasy kickers on the season, but has seen its defense come to life in the past month. The Ravens have held their past three opponents to an average of 13 points, and they enter the game with a few days of added rest after playing the Thursday night game in Week 9. Minnesota quarterback J.J. McCarthy performed admirably in a big win at Detroit, but he's started only three times in his career, and some bumps in the road should be expected. Reichard has been excellent overall, however, making 16-of-18 field goal attempts, but a tough-to-predict Vikings offense makes him a middling fantasy option.

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Chicago Bears second-year wide receiver Rome Odunze (ankle, heel) upgraded to a full practice on Friday and has been cleared to play this Sunday against the visiting New York Giants in Week 10, according to the team. Odunze played through a heel in last week's win over the Cincinnati Bengals and added an ankle injury on Sunday. The 23-year-old did not practice on Wednesday and was limited on Thursday before upgrading to full practice on Friday. It's good news that he won't be missing this weekend's tilt, but fantasy managers have to be a little concerned that Odunze didn't have a single catch last week despite the team putting up 47 points against a porous Bengals defense. Despite the donut in Week 9, fantasy managers should have Odunze in their starting lineups this weekend, as he's tied for the team lead in targets (31) and leads the Bears in receptions (59), receiving yards (473), and touchdowns (five) in eight games this year.

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Minnesota Vikings tight end T.J. Hockenson should be considered a low-end TE2 option with his team taking on the Baltimore Ravens in Week 10. The veteran burned his former team, the Detroit Lions, with a touchdown catch last week, but Minnesota completed only 14 passes for 143 yards behind first-time starting quarterback J.J. McCarthy, albeit in a big victory. The Ravens currently rank 10th against half-PPR tight ends, and Baltimore has held its past three opponents to an average of 13 points. In McCarthy's three starts this year, Hockenson has a total of 10 targets, and there could be more bumps in the road with what is effectively a rookie quarterback learning on the fly. Hockenson is still a distant third in the Vikings' passing game pecking order behind receivers Justin Jefferson and Jordan Addison, so relying upon the tight end is a tough sell this week.

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Cleveland Browns quarterback Dillon Gabriel will come out of his bye to face off against the New York Jets on the road in Week 10. Gabriel has shown a limited fantasy ceiling this season, passing for 702 yards, five touchdowns, and two interceptions in six games (four starts). The Jets have struggled against opposing passing games this season, allowing the 11th-most fantasy points per game, and that was before they traded Sauce Gardner and Quinnen Williams at Tuesday's NFL trade deadline. That being said, the Cleveland offense has been one of the least impressive units in the league. Gabriel settles in as a QB3 in fantasy heading into Week 10 even in a prime matchup against a gutted New York defense.

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San Francisco 49ers quarterback Brock Purdy (toe) is officially listed as questionable for the Week 10 game this Sunday against the division-rival Los Angeles Rams, according to Cam Inman of the Bay Area News Group. Inman also reports that Mac Jones will make his eighth start of the year, so if Purdy is active this weekend, it will be in a backup role. The 25-year-old Purdy has yet to practice in full since aggravating a turf-toe injury back in the Week 4 loss to the Jacksonville Jaguars, so he won't be given the starting gig back just yet. Purdy is getting closer to playing just his third game of the year, but it's unclear if he'll be back to face the division-rival Arizona Cardinals in Week 11. Fantasy managers who have been stashing him this entire time may be running out of patience, but it's been made clear he's the Niners' starter under center when he's past his turf-toe injury. In his two games played this year, Purdy has gone 48-for-73 passing for 586 yards, four touchdowns, and four interceptions.

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Los Angeles Chargers quarterback Justin Herbert enters Week 10 aiming to maintain his efficient performance against a Pittsburgh Steelers defense that has shown vulnerabilities through the air. Despite Pittsburgh ranking last in passing yards allowed per game and 27th in fantasy points per dropback on deep passes, they recently improved by beating the league's top offense, the Indianapolis Colts, last week. Herbert's protection remains a significant concern, with tackle Joe Alt out for the season, and the Chargers trading for the inconsistent yet necessary Trevor Penning. The offensive line, which allowed six sacks last week, has forced Herbert (who already leads all quarterbacks in rushing yards) to use his legs to extend plays and gain yardage. After a solid 250-yard, three-touchdown performance, Herbert's efficiency and rushing floor make him a strong start. RotoBaller projects Herbert as QB5 this week, and he remains a high-end QB1.

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Cleveland Browns running back Quinshon Judkins suffered a shoulder injury in a Week 8 loss to the New England Patriots, but he comes out of his Week 9 bye without an injury designation. He should be in line to handle his normal workload in a Week 10 road matchup against the New York Jets. The Jets have struggled against running backs this season, allowing the seventh-most fantasy points per game to the position. A Tuesday trade of Quinnen Williams to the Dallas Cowboys won't help matters much as New York looks to try to slow down Judkins. The Browns have a good shot at beating or at least keeping things close against the Jets in Week 10, which makes Judkins less likely to see a poor game script limit his touches. He sets up as a low-end RB1 in fantasy heading into Week 10.

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Seattle Seahawks tight end AJ Barner (calf) is listed as questionable to play on Sunday against the division-rival Arizona Cardinals in Week 10 due to a calf injury, per ESPN's Brady Henderson. However, Barner has a good chance of being active this weekend after upgrading to a full practice on Friday. He had his reps limited in practice on both Wednesday and Thursday due to a calf issue. The 23-year-old should be active this Sunday against the Cardinals and will continue his role as Seattle's top pass-catching tight end. Barner has taken on a bigger role in the passing time in his sophomore season in 2025, catching 21 of his 26 targets for 236 yards and four touchdowns in eight starts. His next touchdown will be a new season high after he posted a 30-245-4 line in 17 games in 2024. Treat Barner as a TE2 streamer this weekend in fantasy if he's active.

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The disappointing season continues for San Francisco 49ers wide receiver Ricky Pearsall (knee), as he was officially ruled out for the Week 10 contest on Sunday versus the division-rival Los Angeles Rams, according to Cam Inman of the Bay Area News Group. Pearsall hasn't practiced since suffering a PCL sprain in his knee in the Week 4 loss to the Jacksonville Jaguars and will now miss a sixth straight game. The 25-year-old former first-rounder has quickly developed a reputation as being injury-prone and a slow healer. It's unclear if he'll have a chance to make his return in the Week 11 divisional matchup against the Arizona Cardinals, but Pearsall will have to first get back on the practice field. Jauan Jennings and Kendrick Bourne will continue to serve as the team's top two receivers this weekend, with quarterback Mac Jones likely to make another start in place of the injured Brock Purdy (toe).

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Seattle Seahawks rookie wide receiver Tory Horton (groin, shin) missed practice on Thursday and Friday and is considered doubtful to suit up this Sunday against the division-rival Arizona Cardinals in Week 10, according to Brady Henderson of ESPN. Horton was a full practice participant on Wednesday before being downgraded for the final two days of practice this week. The good news for Seattle is that veteran wideout Cooper Kupp (hamstring, heel) is trending toward playing after missing the Week 9 win over the Washington Commanders. The Seahawks also acquired Rashid Shaheed from the New Orleans Saints at Tuesday's trade deadline, and he could immediately become Seattle's WR2 behind Jaxon Smith-Njigba. Horton has five touchdowns in his first eight NFL games, including two last week, but his fantasy stock is down with Kupp returning and Shaheed joining the fold for the rest of the year.

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The Los Angeles Rams will go with Harrison Mevis as their placekicker in Week 10 against the division-rival San Francisco 49ers on Sunday, according to Nate Atkins of The Athletic. Joshua Karty is now the No. 2 kicker, although the Rams will play the kicking situation on a week-to-week basis right now. Atkins writes that the Rams like Mevis for his big leg after he had success in the USFL. Los Angeles signed Mevis to their practice squad earlier this week to compete with the struggling Karty, who has gone 10-for-15 on his field-goal attempts this year and 23-for-26 on extra-point tries in eight games in his second year in the NFL. If it doesn't work out with Mevis, the Rams can turn back to Karty or bring in another kicker from outside the organization. If Mevis proves himself worthy of keeping the job, he could quickly garner fantasy attention in all leagues.

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Tampa Bay Buccaneers wide receiver Tez Johnson has become a viable option in this offense over the last few weeks. It took a few injuries for Johnson to get a chance, but the 23-year-old is showing he deserves to stay in this spot on the depth chart. In Week 8, Johnson hauled in five of his six targets for 43 yards in the win over the New Orleans Saints. The Bucs are still without Chris Godwin (leg) and Mike Evans (shoulder) for this weekend, so Johnson should continue seeing a high volume of passes coming his way. The rookie wideout should be able to offer flex value for the upcoming Week 10 matchup against the New England Patriots.

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Tampa Bay Buccaneers tight end Cade Otton is hopeful to stay involved during the upcoming Week 10 matchup against the New England Patriots. Otton got off to an awful start to the season, but has seen his role in the offense increase in recent weeks. The 26-year-old has finished with 50 receiving yards or more in three of his last four games. The Bucs are still without multiple wide receivers on offense, so Otton should continue seeing a high volume this weekend. He has done enough on the field to warrant a TE2 play for this weekend.

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Seattle Seahawks wide receiver Cooper Kupp (hamstring, heel) is listed as questionable to play in Week 10 against the Arizona Cardinals on Sunday, according to Brady Henderson of ESPN. However, Kupp was a full participant in Friday's practice, so it sounds like he'll have a good chance of playing after he sat out in the Week 9 win over the Washington Commanders with hamstring and heel injuries. Meanwhile, rookie Tory Horton (shin), who had two touchdowns last week with Kupp sidelined, is listed as doubtful to play this weekend. The 32-year-old Kupp could see more targets in the passing game with Horton likely out, but newly acquired wideout Rashid Shaheed could also step in immediately to become the WR2 behind Jaxon Smith-Njigba. Kupp could see the field plenty this Sunday, but either way, the former third-rounder profiles as a shaky WR4/flex. The vast majority of quarterback Sam Darnold's targets are going to JSN this year, leaving Kupp with only 24 catches for 293 yards and one touchdown in seven games.

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Tampa Bay Buccaneers wide receiver Emeka Egbuka has seen a significant drop-off since his tremendous start to the season. Over the last three games, Egbuka has been held to under 50 receiving yards in two of those contests. The targets have been there, but the rookie wideout and quarterback Baker Mayfield haven't been on the same page lately. It's worth noting that Egbuka was nursing a hamstring injury, so hopefully he's back to full health after the bye week. The Bucs will need Egbuka to rebound this weekend against the New England Patriots. Fantasy managers need to keep plugging Egbuka into their lineups and hope he's able to get back to his elite ways.

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Tampa Bay Buccaneers running back Rachaad White is in line to make another start versus the New England Patriots in Week 10. White came out strong once Bucky Irving (shoulder, foot) went down in Week 4. However, White has been held in check over the last few weeks. In each of the last two games, White has been held to 38 rushing yards or fewer in both contests. The 26-year-old hasn't done much in the receiving game either, so he has been a dud in fantasy leagues over the last few weeks. It's unlikely going to get much better for White this weekend against the Pats who have done a tremendous job at stopping the run this season. Despite that, the Bucs are limited in terms of offensive weapons and will need to get White involved. The 26-year-old should be able to offer RB2 value in PPR formats this weekend.

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Tampa Bay Buccaneers running back Sean Tucker saw a season-high 12 touches during the Week 8 win over the New Orleans Saints. Before that, Tucker had seen a minimal role in this offense even with Bucky Irving (shoulder, toe) sidelined over the last few weeks. Tucker rushed 12 times for 42 yards and scored a touchdown in the Week 8 victory. It's unclear how much he'll be involved on the ground against a tough New England Patriots run defense in Week 10. There's not a ton of upside here, but Tucker could offer low-end flex value in certain formats.

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Los Angeles Chargers rookie running back Omarion Hampton (ankle) worked off to the side at Friday's practice, according to Daniel Popper of The Athletic. Hampton appears to be making progress in his recovery after an extended period with no positive updates. The rookie running back was placed on Injury Reserve after suffering an ankle injury in Week 5 against the Washington Commanders. Head coach Jim Harbaugh said on Monday that he doesn't expect Hampton's 21-day practice window to be opened until after the Chargers' Week 12 bye. Second-year back Kimani Vidal has played well in Hampton's absence and will continue to be a decent RB2/flex option until Hampton is activated from IR to take over the RB1 duties in a few weeks.

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