Miami Dolphins wide receiver Jaylen Waddle was not traded at the deadline, so he'll remain the top target for Tua Tagovailoa in Miami as they host the Bills in Week 10. Waddle has been heavily targeted since the season-ending injury to Tyreek Hill (knee), and he has been the best Dolphins' receiver for fantasy. He has at least five catches in four of his last five games, with the one exception being the bad-weather game in Cleveland. He has at least 80 yards in four of his last five games, along with two of his four touchdowns on the year. He had five catches for 39 yards and a touchdown against the Bills in their first meeting this season, and he'll look to most an even better game at home in the rematch this week. He's the WR18 in RotoBaller's rankings, and he brings both a high floor and a high ceiling since he gets so many targets from Tua and has been a PPR beast.

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Pittsburgh Steelers rookie running back Kaleb Johnson was going as a late-round flier with upside in fantasy drafts this fall, but he was quickly sent to the waiver wire. The 22-year-old third-rounder out of Iowa has been a distant third on Pittsburgh's RB depth chart behind Jaylen Warren and Kenneth Gainwell this year, and he didn't help himself with a costly special-teams blunder early in the season. So far through his first five NFL games, Johnson has handled only 15 rushing attempts for 40 yards (2.7 yards per carry) while catching one of his two targets for nine yards. He played five offensive snaps in last week's win over the Indianapolis Colts, which was actually an improvement after not playing at all the previous two games. It will take an injury to Warren or Gainwell for Johnson to get more involved, which means he's only stash-worthy in fantasy football in dynasty/keeper leagues.

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Miami Dolphins running back Jaylen Wright has hardly gotten any playing time this season, but with Ollie Gordon II (ankle) questionable for Week 10, it could be time for Wright to finally re-enter the rotation. Wright didn't have any carries or catches all season until Week 8, when he had nine carries for 28 yards and a reception for no receiving yards against the Falcons. Last Thursday in Week 9, he was back out of the rotation as a healthy inactive against the Ravens. Last year, the fourth-rounder had 249 yards on his 68 carries, but this year, he hasn't been able to crack the rotation. If Gordon is out or limited, he could get a few carries against Buffalo, but he's not much of a fantasy option at this point, since he's still just the RB78 in RotoBaller's Week 10 rankings.

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Miami Dolphins running back Ollie Gordon II (ankle) is questionable for Sunday's divisional showdown with the Bills after being limited in practice all week. The injury occurred last Thursday against Baltimore, but even the extra time hasn't helped him be 100%. He was starting to get more consistent work behind De'Von Achane, including a 10-carry, 46-yard performance in Week 8 against Atlanta. On the season, Gordon II has logged 122 rushing yards and 30 receiving yards while scoring a pair of touchdowns. If he's limited or out, Jaylen Wright would likely take over as Miami's primary backup running back. Even if he's healthy, he'll be a touchdown-dependent flier play behind workhorse De'Von Achane. He's the No. 48 RB this week, so he shouldn't be started in all but the deepest of formats.

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Tennessee Titans rookie tight end Gunnar Helm has teased fantasy upside in his first NFL season and scored his first career touchdown in the Week 8 loss to the Indianapolis Colts. However, Helm followed that up with one catch for 15 yards in last week's loss to the Los Angeles Chargers. The 23-year-old has a bright future, but in a struggling Titans offense led by rookie quarterback Cameron Ward, he hasn't been much more than a TE3 with upside in fantasy leagues this year. The fourth-round selection out of Texas enters the Week 10 bye with 20 total catches for 187 yards and one touchdown on his 25 targets. Helm is really not much more than a dynasty/keeper stash for the time being, as long as Chig Okonkwo stays healthy. With that said, Tennessee may look to get Helm more involved in the offense for the second half of the season.

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Miami Dolphins running back De'Von Achane continues to be an elite option in a struggling offense, coming into his Week 10 matchup with the Bills. Achane could get even more work than normal with Ollie Gordon II (ankle) questionable and some extra rest since the Dolphins last played on Thursday Night Football over a week ago. Achane rushed 14 times for 67 yards in the Dolphins' Week 9 loss to the Ravens, adding six receptions for 39 yards. He had 12 carries for 62 yards and seven catches for 29 yards the first time he faced Buffalo this season, and he should be very busy once again on Sunday at home. He has seven touchdowns in nine games this season, and his consistent PPR involvement keeps both his floor and ceiling very high. He has logged double-digit carries every week since Week 1, while racking up 56 targets in those seven games. This week, he is the No. 4 RB in RotoBaller's rankings, making him an elite start in all formats.

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Pittsburgh Steelers running back Kenneth Gainwell heads into a Sunday night game in Week 10 against the Los Angeles Chargers with 52 carries for 220 yards and three rushing touchdowns in eight games in his first year in the Steel City. He has added 27 catches for 119 yards on 31 targets. Gainwell lost a yard on his three rushing attempts in the upset win over the Indianapolis Colts in Week 9, but he did tie a season high with 35 receiving yards on his four receptions. The 26-year-old also played 37% of the offensive snaps to rookie Kaleb Johnson's 8%, signaling that he's still the team's clear RB2 behind starter Jaylen Warren. Gainwell hasn't seen enough volume to make him a standalone starting option in fantasy behind Warren, but he's a decent handcuff in PPR leagues. If Warren were to go down with an injury, Gainwell would be a priority waiver-wire pickup.

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Jacksonville Jaguars wide receiver Dyami Brown (concussion) practiced in full on Friday, cleared the league's concussion protocol, and will be active on Sunday for a Week 10 divisional clash against the Houston Texans. Brown suffered a concussion in last week's overtime win over the Las Vegas Raiders, but he will play this weekend and will have an expanded role in the passing game with rookie first-rounder Travis Hunter (knee) on Injured Reserve and Brian Thomas Jr. (ankle) ruled out this weekend. The 26-year-old hasn't done much in his first year with the Jags in 2025, catching 19 of his 34 targets for 219 yards and one touchdown in seven games. However, he'll be in play as a WR4/flex, albeit against one of the best defenses in the NFL, this weekend with both Hunter and Thomas sidelined by injuries. In addition to Brown, Parker Washington and the newly acquired Jakobi Meyers should be Jacksonville's top three wideouts.

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Chicago Bears wide receiver DJ Moore (groin, hip) upgraded to a full practice on Friday and has been cleared to play this Sunday against the visiting New York Giants in Week 10. Moore was held out of practice on Wednesday and was limited on Thursday before being a full-go in the final practice of the week. The 28-year-old has battled injuries in recent weeks, but he hasn't missed any games and will be full speed ahead this weekend in a good matchup against the G-Men. Moore has mostly taken a back seat to second-year wideout Rome Odunze in 2025, but that wasn't the case in the team's 47-point explosion in the Week 9 win over the Cincinnati Bengals. He had four catches for 72 yards, a 17-yard rushing touchdown, and even threw a touchdown pass on a track play, while Odunze didn't have a single catch. Moore has only two touchdowns on the year, but he has topped 70 receiving yards for the first time all year in two straight games. Fantasy managers will be hoping that trend continues as a low-end WR2/high-end WR3/flex in Week 10.

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Washington Commanders running back Jeremy McNichols only had one carry for four yards, but he added a season-high five catches on six targets for 64 receiving yards in the Week 8 loss to the Kansas City Chiefs while playing a season-high 43% of the offensive snaps. The 29-year-old couldn't stack another strong game on top of it, though, as he played only 26% of the snaps in the Week 9 loss to the Seattle Seahawks and wasn't targeted through the air. McNichols had just one carry again for no gain. It was the first time he was held without a catch since back in Week 3. Fantasy managers definitely can't realistically treat McNichols as a starting option, but both he and Chris Rodriguez Jr. may start to see more involvement with rookie Jacory Croskey-Merritt hitting a rookie wall. On the year, McNichols has only 272 scrimmage yards and a touchdown on 29 touches.

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San Francisco 49ers wide receiver Ricky Pearsall (knee) has been running, but he hasn't quite been cleared to make his return after spraining his PCL in the Week 4 loss to the Jacksonville Jaguars, according to Cam Inman of the Bay Area News Group. "He can run and hit certain speeds. But he hasn't been able to hit his normal speeds that would allow him to come back. We're waiting until he hits his markers," head coach Kyle Shanahan said. Pearsall was officially ruled out for Week 10 this Sunday against the division-rival Los Angeles Rams, his sixth straight absence. The 25-year-old was a popular breakout candidate during training camp and the preseason this year, with Brandon Aiyuk (knee) recovering from a torn ACL and MCL, but injury issues of his own have limited him to just four games, and he's running out of time to make an impact for his fantasy managers. Pearsall must get back on the practice field next week to have a chance at playing in Week 11 against the Arizona Cardinals.

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Washington Commanders wide receiver Terry McLaurin (quadriceps) did not practice all week and has officially been ruled out for Week 10 against the visiting Detroit Lions, according to Ben Standig. McLaurin suffered a quad injury in Week 4 and missed four games before returning in Week 8. The 30-year-old veteran aggravated the injury upon his return, and now he'll miss a second straight game. There have been reports suggesting that he may be out beyond the team's Week 12 bye, too, so fantasy managers could be without McLaurin beyond this weekend. The Commanders are extremely banged up heading into Week 10, as quarterback Jayden Daniels (elbow) and receiver Luke McCaffrey (collarbone) are out for the foreseeable future. Veteran Deebo Samuel Sr. is going to be force-fed targets, while rookie Jaylin Lane will also have an increased role in the passing attack in D.C. going forward.

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Los Angeles Chargers running back Jaret Patterson was called up from the practice squad and made an immediate impact, leading the backfield with 44 yards on nine carries (4.9 YPC) in last week's win over the Tennessee Titans. Although he outperformed Kimani Vidal in efficiency, Vidal remains the primary back. Additionally, Patterson is not heavily involved in the passing game, which limits his weekly floor. He continues to serve as a change-of-pace option, and while he is seeing more snaps, the Pittsburgh Steelers present a tough matchup on the ground. With Hassan Haskins (hamstring) and Omarion Hampton (ankle) on IR until after the Week 12 bye, Patterson is a potential stash for managers in deep leagues, but he should stay on the bench for Week 10.

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Los Angeles Chargers rookie wide receiver Tre' Harris has recently seen his role grow, holding about a 50% snap share and catching two passes for 18 yards last week in the team's win over the Tennessee Titans. Although he made a clutch first-down catch to help secure the victory, he remains part of a crowded receiver group with several proven pass-catchers ahead of him. Facing the surging Pittsburgh Steelers defense, Harris's chances for a significant fantasy performance are limited. While the questionable injury status of fellow rookie KeAndr Lambert-Smith (hamstring) could slightly increase his route participation, the presence of established receivers limits his weekly volume. Harris should still be a deep-league stash, but probably shouldn't be in starting lineups this week.

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Miami Dolphins quarterback Tua Tagovailoa continues to struggle at the helm of the Dolphins' offense, but he'll continue to start this week in a home game against the Bills. Last week, he threw for 261 passing yards and one interception on Thursday Night Football against the Ravens. He didn't throw any touchdowns, and he has one or zero scores in three of the last four weeks, with the one exception being his strong showing against the Falcons. He's averaging only 6.6 yards per attempt and 197.7 yards per game, and the Bills have allowed the second-fewest fantasy points to quarterbacks this season. He had 146 yards, two touchdowns, and an interception against the Bills in Week 3. His recent struggles without Tyreek Hill drop him all the way down to QB24 this week, meaning he should barely be starting in two-QB leagues even with bye weeks.

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Green Bay Packers wide receiver Matthew Golden (shoulder) was unable to take part in practice on Friday. Golden was forced to make an early exit during the Week 9 loss to the Carolina Panthers. The rookie wideout was limited in practice on Thursday before being downgraded to out on Friday. He'll get another day to get ready ahead of the Monday night matchup against the Philadelphia Eagles. If he's unable to play, Romeo Doubs, Christian Watson, and Dontayvion Wicks would all see larger roles.

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Los Angeles Rams wide receiver Puka Nacua (ribs) has been cleared to play ahead of the Week 10 matchup against the San Francisco 49ers. Nacua was limited to begin the week, but was able to finish out the week with two straight full practice sessions. Barring any setbacks, Nacua will be out there in full capacity for this weekend's divisional matchup. When healthy, Nacua has been unbelievable on the field, so he'll obviously need to be started in all fantasy formats this weekend.

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Minnesota Vikings running back Jordan Mason faces a friendly matchup against a Baltimore Ravens team that has struggled to stop the run for large portions of the year, but it remains to be seen how the Vikings will allocate carries in their backfield in Week 10. Fellow running back Aaron Jones Sr. (shoulder, toe) left last week's game and is questionable to play against the Ravens, which offers a range of possibilities for Mason. Jones was the more effective option last week in a key victory against Detroit, and though Minnesota head coach Kevin O'Connell has expressed optimism about Jones playing this week, Mason would be the featured option if Jones were to miss the game. The Vikings have ridden the hot hand when both backs have been available, which can be challenging to predict for fantasy purposes. But with Mason facing a good matchup and still getting a reasonable amount of work alongside Jones, he's a playable RB3/flex option in most formats.

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Cleveland Browns wide receiver Cedric Tillman (hamstring) has practiced fully all week and is expected to make his return in Week 10 after a four-week stay on injured reserve due to a hamstring injury. If Tillman ultimately ends up playing, he will make his return on the road against the New York Jets. The veteran got off a fast start in 2025, catching touchdowns in each of his first two games, although his production tailed off in Weeks 3 and 4 before his hamstring issue. The Jets' secondary should be vulnerable after they traded Sauce Gardner to the Indianapolis Colts on Tuesday at the NFL trade deadline. That being said, the Cleveland passing attack hasn't inspired much confidence with Dillon Gabriel at the helm, leaving Tillman as a WR5/desperation flex in fantasy heading into Week 10.

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Houston Texans running back Nick Chubb (foot) doesn't carry an injury designation into Sunday's Week 10 matchup against the Jacksonville Jaguars. Chubb sat out practice to begin the week, but was able to return as a limited participant on Thursday. Now, Chubb has been removed from the injury report ahead of this divisional matchup. The 29-year-old figures to continue splitting up the backfield duties with Woody Marks. There has been a fairly even split between the two backs in recent weeks. That being said, both backs will have limited value until one pulls ahead as the lead back.

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