

| Benched | RB | Zach Charbonnet SEA | Owner | Tue Nov 25 8:23pm CT |
| Benched | WR | Jameson Williams DET | Owner | Tue Nov 25 8:23pm CT |
| Benched | TE | Cade Otton TB | Owner | Tue Nov 25 8:23pm CT |
| Started | RB | Josh Jacobs GB | Owner | Tue Nov 25 8:23pm CT |
| Started | RB | Kimani Vidal LAC | Owner | Tue Nov 25 8:23pm CT |
| Started | TE | Colby Parkinson LAR | Owner | Tue Nov 25 8:23pm CT |
| Benched | WR | Wan'Dale Robinson NYG | Owner | Fri Nov 28 4:00pm CT |
| Started | TE | Juwan Johnson NO | Owner | Fri Nov 28 4:00pm CT |
| Benched | TE | Juwan Johnson NO | Owner | Wed Nov 26 11:36pm CT |
| Started | WR | Wan'Dale Robinson NYG | Owner | Wed Nov 26 11:36pm CT |
| Benched | WR | Tre Tucker LV | Owner | Fri Nov 28 10:44am CT |
| Started | WR | Marvin Harrison Jr. ARI | Owner | Fri Nov 28 10:44am CT |
| Benched | TE | Noah Fant CIN | Owner | Wed Nov 26 6:10pm CT |
| Started | WR | Davante Adams LAR | Owner | Wed Nov 26 6:10pm CT |
| Benched | WR | Romeo Doubs GB | Owner | Thu Nov 27 5:33am CT |
| Benched | WR | Xavier Legette CAR | Owner | Thu Nov 27 5:33am CT |
| Started | RB | Bucky Irving TB | Owner | Thu Nov 27 5:33am CT |
| Started | WR | Deebo Samuel WAS | Owner | Thu Nov 27 5:33am CT |
| Benched | QB | J.J. McCarthy MIN | Owner | Wed Nov 26 6:11pm CT |
| Benched | WR | Jalen Coker CAR | Owner | Wed Nov 26 6:11pm CT |
| Benched | WR | Darius Slayton NYG | Owner | Wed Nov 26 6:11pm CT |
| Started | QB | Bo Nix DEN | Owner | Wed Nov 26 6:11pm CT |
| Started | WR | Jayden Higgins HOU | Owner | Wed Nov 26 6:11pm CT |
| Started | WR | Jaylen Waddle MIA | Owner | Wed Nov 26 6:11pm CT |
| Started | TE | Brenton Strange JAX | Owner | Wed Nov 26 6:11pm CT |
| Benched | QB | Daniel Jones IND | Owner | Wed Nov 26 11:11pm CT |
| Benched | WR | Tee Higgins CIN | Owner | Wed Nov 26 11:11pm CT |
| Started | QB | Justin Herbert LAC | Owner | Wed Nov 26 11:11pm CT |
| Started | TE | Theo Johnson NYG | Owner | Wed Nov 26 11:11pm CT |
| Benched | WR | Cooper Kupp SEA | Owner | Thu Nov 27 11:59am CT |
| Started | TE | AJ Barner SEA | Owner | Thu Nov 27 11:59am CT |
| Benched | WR | Tyrell Shavers BUF | Owner | Wed Nov 26 6:32pm CT |
| Benched | TE | AJ Barner SEA | Owner | Wed Nov 26 6:32pm CT |
| Started | WR | Ladd McConkey LAC | Owner | Wed Nov 26 6:32pm CT |
| Started | WR | D.J. Moore CHI | Owner | Wed Nov 26 6:32pm CT |
| Started | QB | Trevor Lawrence JAX | Owner | Wed Nov 26 3:00pm CT |
| Benched | QB | Bryce Young CAR | Owner | Wed Nov 26 3:00pm CT |
| Started | TE | Evan Engram DEN | Owner | Tue Nov 25 2:27pm CT |
| Benched | TE | Colston Loveland CHI | Owner | Tue Nov 25 2:27pm CT |
| Started | QB | Bryce Young CAR | Owner | Tue Nov 25 2:26pm CT |
| Benched | QB | Trevor Lawrence JAX | Owner | Tue Nov 25 2:26pm CT |
| Started | WR | Troy Franklin DEN | Owner | Tue Nov 25 2:23pm CT |
| Started | WR | Ja'Marr Chase CIN | Owner | Tue Nov 25 2:23pm CT |
| Started | RB | Devon Achane MIA | Owner | Tue Nov 25 2:23pm CT |
| Benched | WR | Darnell Mooney ATL | Owner | Tue Nov 25 2:23pm CT |
| Benched | WR | Xavier Hutchinson HOU | Owner | Tue Nov 25 2:23pm CT |
| Benched | RB | Tyler Allgeier ATL | Owner | Tue Nov 25 2:23pm CT |
| Benched | TE | Dalton Kincaid BUF | Owner | Sun Nov 30 9:40am CT |
| Started | WR | Elic Ayomanor TEN | Owner | Sun Nov 30 9:40am CT |
| Benched | TE | Elijah Arroyo SEA | Owner | Thu Nov 27 11:43am CT |
| Started | TE | Zach Ertz WAS | Owner | Thu Nov 27 11:43am CT |
| Started | TE | Dalton Kincaid BUF | Owner | Thu Nov 27 11:43am CT |
| No starting lineup changes performed this week. |
| No starting lineup changes performed this week. |
| Started | RB | Rachaad White TB | Owner | Thu Nov 27 5:30am CT |
| Benched | RB | Brashard Smith KC | Owner | Thu Nov 27 5:30am CT |
| Started | RB | Brashard Smith KC | Owner | Thu Nov 27 5:29am CT |
| Benched | RB | Emanuel Wilson GB | Owner | Thu Nov 27 5:29am CT |
| Started | WR | Greg Dortch ARI | Owner | Thu Nov 27 5:29am CT |
| Benched | WR | Mack Hollins NE | Owner | Thu Nov 27 5:29am CT |
| Started | WR | Keenan Allen LAC | Owner | Thu Nov 27 5:28am CT |
| Benched | WR | Greg Dortch ARI | Owner | Thu Nov 27 5:28am CT |
| Started | WR | Courtland Sutton DEN | Owner | Thu Nov 27 5:28am CT |
| Benched | RB | Alvin Kamara NO | Owner | Thu Nov 27 5:28am CT |