

| Benched | WR | Alec Pierce IND | Owner | Sun Nov 30 11:20am CT |
| Started | WR | Marvin Harrison Jr. ARI | Owner | Sun Nov 30 11:20am CT |
| No starting lineup changes performed this week. |
| Benched | QB | Jordan Love GB | Owner | Wed Nov 26 11:05am CT |
| Benched | K | Cairo Santos CHI | Owner | Wed Nov 26 11:05am CT |
| Started | QB | Bo Nix DEN | Owner | Wed Nov 26 11:05am CT |
| Started | K | Cameron Dicker LAC | Owner | Wed Nov 26 11:05am CT |
| Benched | RB | Emanuel Wilson GB | Owner | Thu Nov 27 10:14am CT |
| Benched | WR | DeVonta Smith PHI | Owner | Thu Nov 27 10:14am CT |
| Started | RB | Devon Achane MIA | Owner | Thu Nov 27 10:14am CT |
| Started | WR | Ja'Marr Chase CIN | Owner | Thu Nov 27 10:14am CT |
| Benched | QB | Brock Purdy SF | Owner | Wed Nov 26 8:36am CT |
| Benched | RB | David Montgomery DET | Owner | Wed Nov 26 8:36am CT |
| Benched | WR | Tre Tucker LV | Owner | Wed Nov 26 8:36am CT |
| Benched | WR | Jameson Williams DET | Owner | Wed Nov 26 8:36am CT |
| Started | QB | Joe Burrow CIN | Owner | Wed Nov 26 8:36am CT |
| Started | RB | RJ Harvey DEN | Owner | Wed Nov 26 8:36am CT |
| Started | RB | Isiah Pacheco KC | Owner | Wed Nov 26 8:36am CT |
| Started | WR | Ladd McConkey LAC | Owner | Wed Nov 26 8:36am CT |
| Started | D/ST | Los Angeles Rams LAR | Owner | Thu Nov 27 7:39am CT |
| Benched | D/ST | Philadelphia Eagles PHI | Owner | Thu Nov 27 7:39am CT |
| Started | D/ST | Philadelphia Eagles PHI | Owner | Tue Nov 25 2:25pm CT |
| Started | RB | Bucky Irving TB | Owner | Tue Nov 25 2:25pm CT |
| Benched | D/ST | Baltimore Ravens BAL | Owner | Tue Nov 25 2:25pm CT |
| Benched | WR | Troy Franklin DEN | Owner | Tue Nov 25 2:25pm CT |
| Started | WR | Troy Franklin DEN | Owner | Tue Nov 25 6:08am CT |
| Benched | RB | D'Andre Swift CHI | Owner | Tue Nov 25 6:08am CT |
| Started | D/ST | Baltimore Ravens BAL | Owner | Tue Nov 25 6:07am CT |
| Benched | D/ST | Detroit Lions DET | Owner | Tue Nov 25 6:07am CT |
| No starting lineup changes performed this week. |
| Benched | RB | Travis Etienne JAX | Owner | Wed Nov 26 7:19am CT |
| Started | WR | Zay Flowers BAL | Owner | Wed Nov 26 7:19am CT |