

| Benched | WR | Rome Odunze CHI | Owner | Thu Nov 27 1:57am CT |
| Benched | WR | Michael Pittman Jr. IND | Owner | Thu Nov 27 1:57am CT |
| Started | RB | RJ Harvey DEN | Owner | Thu Nov 27 1:57am CT |
| Started | WR | Ladd McConkey LAC | Owner | Thu Nov 27 1:57am CT |
| Benched | RB | Alvin Kamara NO | Owner | Tue Nov 25 2:27pm CT |
| Started | WR | Deebo Samuel WAS | Owner | Tue Nov 25 2:27pm CT |
| No starting lineup changes performed this week. |
| No starting lineup changes performed this week. |
| Benched | WR | Jauan Jennings SF | Owner | Wed Nov 26 12:55pm CT |
| Started | WR | Romeo Doubs GB | Owner | Wed Nov 26 12:55pm CT |
| Benched | WR | Marvin Harrison Jr. ARI | Owner | Wed Nov 26 12:55pm CT |
| Started | WR | Jauan Jennings SF | Owner | Wed Nov 26 12:55pm CT |
| Benched | WR | Jauan Jennings SF | Owner | Tue Nov 25 3:05pm CT |
| Benched | TE | Dallas Goedert PHI | Owner | Tue Nov 25 3:05pm CT |
| Started | RB | Josh Jacobs GB | Owner | Tue Nov 25 3:05pm CT |
| Started | WR | Marvin Harrison Jr. ARI | Owner | Tue Nov 25 3:05pm CT |
| Benched | RB | Chris Rodriguez Jr. WAS | Owner | Sat Nov 29 6:54am CT |
| Started | WR | Terry McLaurin WAS | Owner | Sat Nov 29 6:54am CT |
| Started | RB | Chris Rodriguez Jr. WAS | Owner | Thu Nov 27 6:44am CT |
| Started | D/ST | Philadelphia Eagles PHI | Owner | Thu Nov 27 6:43am CT |
| Benched | RB | Emanuel Wilson GB | Owner | Tue Nov 25 10:18am CT |
| Benched | WR | Tee Higgins CIN | Owner | Tue Nov 25 10:18am CT |
| Benched | D/ST | Philadelphia Eagles PHI | Owner | Tue Nov 25 10:18am CT |
| Started | RB | Devon Achane MIA | Owner | Tue Nov 25 10:18am CT |
| Started | D/ST | Los Angeles Chargers LAC | Owner | Tue Nov 25 10:18am CT |
| Benched | QB | Jordan Love GB | Owner | Thu Nov 27 9:44am CT |
| Benched | RB | Woody Marks HOU | Owner | Thu Nov 27 9:44am CT |
| Benched | TE | Mark Andrews BAL | Owner | Thu Nov 27 9:44am CT |
| Started | QB | Joe Burrow CIN | Owner | Thu Nov 27 9:44am CT |
| Started | RB | Bucky Irving TB | Owner | Thu Nov 27 9:44am CT |
| Started | TE | Tyler Warren IND | Owner | Thu Nov 27 9:44am CT |
| Started | K | Cameron Dicker LAC | Owner | Thu Nov 27 9:44am CT |
| Benched | WR | Jakobi Meyers JAX | Owner | Fri Nov 28 12:18pm CT |
| Started | WR | DeVonta Smith PHI | Owner | Fri Nov 28 12:18pm CT |
| Benched | WR | DeVonta Smith PHI | Owner | Thu Nov 27 1:19pm CT |
| Started | WR | Jakobi Meyers JAX | Owner | Thu Nov 27 1:19pm CT |
| Benched | D/ST | Atlanta Falcons ATL | Owner | Wed Nov 26 10:09pm CT |
| Started | D/ST | Denver Broncos DEN | Owner | Wed Nov 26 10:09pm CT |
| Benched | QB | Caleb Williams CHI | Owner | Thu Nov 27 11:28pm CT |
| Started | QB | Justin Herbert LAC | Owner | Thu Nov 27 11:28pm CT |
| Started | TE | Zach Ertz WAS | Owner | Thu Nov 27 7:33pm CT |
| Benched | RB | Rhamondre Stevenson NE | Owner | Wed Nov 26 4:55pm CT |
| Benched | WR | Marquise Brown KC | Owner | Wed Nov 26 4:55pm CT |
| Benched | WR | Jerry Jeudy CLE | Owner | Wed Nov 26 4:55pm CT |
| Started | WR | Troy Franklin DEN | Owner | Wed Nov 26 4:55pm CT |
| Started | WR | Courtland Sutton DEN | Owner | Wed Nov 26 4:55pm CT |
| Started | TE | Oronde Gadsden II LAC | Owner | Wed Nov 26 4:55pm CT |
| Benched | QB | Tyler Shough NO | Owner | Wed Nov 26 11:22am CT |
| Benched | TE | Mason Taylor NYJ | Owner | Wed Nov 26 11:22am CT |
| Started | QB | Bo Nix DEN | Owner | Wed Nov 26 11:22am CT |
| Started | WR | Jaylen Waddle MIA | Owner | Wed Nov 26 11:22am CT |
| No starting lineup changes performed this week. |