

| Benched | RB | Tyrone Tracy Jr. NYG | Owner | Sun Nov 30 10:41am CT |
| Started | QB | Baker Mayfield TB | Owner | Sun Nov 30 10:41am CT |
| Benched | RB | D'Andre Swift CHI | Owner | Fri Nov 28 1:01pm CT |
| Started | RB | Kyle Monangai CHI | Owner | Fri Nov 28 1:01pm CT |
| Benched | QB | Baker Mayfield TB | Owner | Wed Nov 26 8:48pm CT |
| Started | RB | Tyrone Tracy Jr. NYG | Owner | Wed Nov 26 8:48pm CT |
| Benched | RB | Blake Corum LAR | Owner | Sat Nov 29 8:15pm CT |
| Started | RB | Chris Rodriguez Jr. WAS | Owner | Sat Nov 29 8:15pm CT |
| Benched | RB | Jordan Mason MIN | Owner | Tue Nov 25 8:27pm CT |
| Benched | WR | Tee Higgins CIN | Owner | Tue Nov 25 8:27pm CT |
| Started | RB | RJ Harvey DEN | Owner | Tue Nov 25 8:27pm CT |
| Started | WR | Malik Washington MIA | Owner | Tue Nov 25 8:27pm CT |
| Benched | WR | Tez Johnson TB | Owner | Wed Nov 26 9:16pm CT |
| Started | WR | Chimere Dike TEN | Owner | Wed Nov 26 9:16pm CT |
| Started | TE | Oronde Gadsden II LAC | Owner | Wed Nov 26 9:16pm CT |
| Benched | RB | Tyjae Spears TEN | Owner | Wed Nov 26 9:15pm CT |
| Benched | WR | Ricky Pearsall SF | Owner | Wed Nov 26 9:15pm CT |
| Started | WR | Tez Johnson TB | Owner | Wed Nov 26 9:15pm CT |
| Benched | TE | Tyler Warren IND | Owner | Sun Nov 30 11:32am CT |
| Started | RB | Devin Neal NO | Owner | Sun Nov 30 11:32am CT |
| Benched | TE | Dallas Goedert PHI | Owner | Tue Nov 25 7:28am CT |
| Started | QB | Justin Herbert LAC | Owner | Tue Nov 25 7:28am CT |
| Started | TE | Darren Waller MIA | Owner | Sun Nov 30 11:43am CT |
| Benched | TE | Mason Taylor NYJ | Owner | Sun Nov 30 11:43am CT |
| Started | TE | Mason Taylor NYJ | Owner | Thu Nov 27 6:02am CT |
| Started | WR | Terry McLaurin WAS | Owner | Thu Nov 27 6:02am CT |
| Benched | WR | Drake London ATL | Owner | Thu Nov 27 5:48am CT |
| Started | WR | Drake London ATL | Owner | Tue Nov 25 4:20pm CT |
| Started | WR | Ja'Marr Chase CIN | Owner | Tue Nov 25 4:20pm CT |
| Benched | WR | Darius Slayton NYG | Owner | Tue Nov 25 4:20pm CT |
| Benched | WR | Van Jefferson TEN | Owner | Tue Nov 25 4:20pm CT |
| Benched | RB | Sean Tucker TB | Owner | Tue Nov 25 4:20pm CT |
| Benched | TE | Brenton Strange JAX | Owner | Fri Nov 28 12:18pm CT |
| Started | WR | DeVonta Smith PHI | Owner | Fri Nov 28 12:18pm CT |
| Benched | WR | DeVonta Smith PHI | Owner | Thu Nov 27 1:19pm CT |
| Started | TE | Brenton Strange JAX | Owner | Thu Nov 27 1:19pm CT |
| No starting lineup changes performed this week. |
| Benched | QB | Aaron Rodgers PIT | Owner | Sun Nov 30 11:23am CT |
| Started | QB | Cam Ward TEN | Owner | Sun Nov 30 11:23am CT |
| Benched | QB | Bryce Young CAR | Owner | Wed Nov 26 11:18pm CT |
| Started | QB | Aaron Rodgers PIT | Owner | Wed Nov 26 11:18pm CT |
| Benched | RB | Devin Singletary NYG | Owner | Thu Nov 27 9:40am CT |
| Benched | WR | Tre Tucker LV | Owner | Thu Nov 27 9:40am CT |
| Started | QB | Bo Nix DEN | Owner | Thu Nov 27 9:40am CT |
| Started | WR | Marvin Harrison Jr. ARI | Owner | Thu Nov 27 9:40am CT |
| Started | TE | Dalton Schultz HOU | Owner | Wed Nov 26 11:04am CT |
| Benched | TE | Zach Ertz WAS | Owner | Wed Nov 26 11:04am CT |
| Started | TE | Zach Ertz WAS | Owner | Tue Nov 25 3:34pm CT |
| Benched | TE | Dalton Schultz HOU | Owner | Tue Nov 25 3:34pm CT |
| Started | WR | Troy Franklin DEN | Owner | Tue Nov 25 6:13am CT |
| Benched | WR | Rashid Shaheed SEA | Owner | Tue Nov 25 6:13am CT |
| Started | WR | Deebo Samuel WAS | Owner | Tue Nov 25 6:13am CT |
| Started | WR | Ladd McConkey LAC | Owner | Tue Nov 25 6:13am CT |
| Started | RB | Devon Achane MIA | Owner | Tue Nov 25 6:13am CT |
| Benched | WR | Mack Hollins NE | Owner | Tue Nov 25 6:13am CT |
| Benched | WR | Jordan Addison MIN | Owner | Tue Nov 25 6:13am CT |
| Benched | RB | Kareem Hunt KC | Owner | Tue Nov 25 6:13am CT |
| No starting lineup changes performed this week. |
| No starting lineup changes performed this week. |