

| No starting lineup changes performed this week. |
| No starting lineup changes performed this week. |
| Started | D/ST | Miami Dolphins MIA | Owner | Thu Nov 27 11:58am CT |
| Benched | RB | Alvin Kamara NO | Owner | Wed Nov 26 10:32pm CT |
| Benched | RB | Sean Tucker TB | Owner | Wed Nov 26 10:32pm CT |
| Benched | WR | Josh Downs IND | Owner | Wed Nov 26 10:32pm CT |
| Benched | WR | Andrei Iosivas CIN | Owner | Wed Nov 26 10:32pm CT |
| Started | RB | Bucky Irving TB | Owner | Wed Nov 26 10:32pm CT |
| Started | RB | Josh Jacobs GB | Owner | Wed Nov 26 10:32pm CT |
| Started | WR | Quentin Johnston LAC | Owner | Wed Nov 26 10:32pm CT |
| Started | TE | Brenton Strange JAX | Owner | Wed Nov 26 10:32pm CT |
| Started | WR | Malik Washington MIA | Owner | Wed Nov 26 11:24pm CT |
| Benched | WR | Sterling Shepard TB | Owner | Tue Nov 25 10:03am CT |
| Started | WR | Jaylen Waddle MIA | Owner | Tue Nov 25 10:03am CT |
| Benched | WR | Christian Watson GB | Owner | Thu Nov 27 11:10am CT |
| Started | WR | Ja'Marr Chase CIN | Owner | Thu Nov 27 11:10am CT |
| Started | K | Jason Myers SEA | Owner | Thu Nov 27 11:10am CT |
| Started | D/ST | Los Angeles Chargers LAC | Owner | Thu Nov 27 11:10am CT |
| Benched | WR | Xavier Legette CAR | Owner | Tue Nov 25 11:05am CT |
| Started | WR | Courtland Sutton DEN | Owner | Tue Nov 25 11:05am CT |
| Benched | RB | Brian Robinson Jr. SF | Owner | Tue Nov 25 11:03am CT |
| Benched | WR | Alec Pierce IND | Owner | Tue Nov 25 11:03am CT |
| Started | RB | Devon Achane MIA | Owner | Tue Nov 25 11:03am CT |
| Started | WR | Xavier Worthy KC | Owner | Tue Nov 25 11:03am CT |
| No starting lineup changes performed this week. |
| Benched | RB | Zonovan Knight ARI | Owner | Wed Nov 26 10:17pm CT |
| Benched | WR | Darnell Mooney ATL | Owner | Wed Nov 26 10:17pm CT |
| Benched | K | Ka'imi Fairbairn HOU | Owner | Wed Nov 26 10:17pm CT |
| Benched | D/ST | Detroit Lions DET | Owner | Wed Nov 26 10:17pm CT |
| Started | RB | Tony Pollard TEN | Owner | Wed Nov 26 10:17pm CT |
| Started | WR | Ladd McConkey LAC | Owner | Wed Nov 26 10:17pm CT |
| Started | K | Cameron Dicker LAC | Owner | Wed Nov 26 10:17pm CT |
| Started | D/ST | Los Angeles Rams LAR | Owner | Wed Nov 26 10:17pm CT |
| Benched | WR | Mack Hollins NE | Owner | Wed Nov 26 9:01am CT |
| Benched | D/ST | Cleveland Browns CLE | Owner | Wed Nov 26 9:01am CT |
| Started | WR | Keenan Allen LAC | Owner | Wed Nov 26 9:01am CT |
| Started | D/ST | Denver Broncos DEN | Owner | Wed Nov 26 9:01am CT |
| No starting lineup changes performed this week. |
| Benched | QB | Baker Mayfield TB | Owner | Thu Nov 27 10:39am CT |
| Benched | WR | Tee Higgins CIN | Owner | Thu Nov 27 10:39am CT |
| Benched | WR | DeVonta Smith PHI | Owner | Thu Nov 27 10:39am CT |
| Started | QB | Joe Burrow CIN | Owner | Thu Nov 27 10:39am CT |
| Started | RB | Kyren Williams LAR | Owner | Thu Nov 27 10:39am CT |
| Started | WR | Deebo Samuel WAS | Owner | Thu Nov 27 10:39am CT |
| Benched | RB | Kimani Vidal LAC | Owner | Thu Nov 27 8:59am CT |
| Started | WR | Jameson Williams DET | Owner | Thu Nov 27 8:59am CT |
| Benched | QB | Jared Goff DET | Owner | Wed Nov 26 8:07am CT |
| Started | QB | Justin Herbert LAC | Owner | Wed Nov 26 8:07am CT |
| Benched | WR | Jameson Williams DET | Owner | Tue Nov 25 8:17am CT |
| Started | RB | Kimani Vidal LAC | Owner | Tue Nov 25 8:17am CT |