Guest of the League
Lineup Changes
*San Francisco 49ers 79 - Richard Shaw
| Benched | RB | Zonovan Knight ARI | Owner | Wed Nov 5 12:53am ET |
| Benched | WR | Dyami Brown JAX | Owner | Wed Nov 5 12:53am ET |
| Benched | WR | Marquise Brown KC | Owner | Wed Nov 5 12:53am ET |
| Started | RB | Jaylen Warren PIT | Owner | Wed Nov 5 12:53am ET |
| Started | WR | Tez Johnson TB | Owner | Wed Nov 5 12:53am ET |
| Started | WR | Christian Kirk HOU | Owner | Wed Nov 5 12:53am ET |
5.1 Michigan Panthers SF - Kenneth Jones
| Benched | RB | Tyjae Spears TEN | Owner | Tue Nov 4 9:23am ET |
| Benched | WR | Elic Ayomanor TEN | Owner | Tue Nov 4 9:23am ET |
| Benched | WR | Xavier Worthy KC | Owner | Tue Nov 4 9:23am ET |
| Started | QB | Baker Mayfield TB | Owner | Tue Nov 4 9:23am ET |
| Started | RB | Breece Hall NYJ | Owner | Tue Nov 4 9:23am ET |
| Started | WR | Matthew Golden GB | Owner | Tue Nov 4 9:23am ET |
ABC - Drew
| No starting lineup changes performed this week. |
Autofill (SF) -
| Benched | QB | Jacoby Brissett ARI | Owner | Tue Nov 4 6:53pm ET |
| Benched | WR | Tee Higgins CIN | Owner | Tue Nov 4 6:53pm ET |
| Benched | WR | Rashee Rice KC | Owner | Tue Nov 4 6:53pm ET |
| Started | QB | Michael Penix Jr. ATL | Owner | Tue Nov 4 6:53pm ET |
| Started | WR | Jameson Williams DET | Owner | Tue Nov 4 6:53pm ET |
| Started | WR | Garrett Wilson NYJ | Owner | Tue Nov 4 6:53pm ET |
Ballbusters 66 - Quinton Fletcher
| Benched | RB | Brashard Smith KC | Owner | Wed Nov 5 9:48am ET |
| Benched | RB | Kenneth Walker III SEA | Owner | Wed Nov 5 9:48am ET |
| Benched | WR | Jalen Coker CAR | Owner | Wed Nov 5 9:48am ET |
| Started | RB | Bucky Irving TB | Owner | Wed Nov 5 9:48am ET |
| Started | RB | Quinshon Judkins CLE | Owner | Wed Nov 5 9:48am ET |
| Started | WR | Emeka Egbuka TB | Owner | Wed Nov 5 9:48am ET |
FarmerTed 125B - Vincent Van Delay
| Benched | QB | Joe Flacco CIN | Owner | Wed Nov 5 8:33pm ET |
| Benched | WR | George Pickens DAL | Owner | Wed Nov 5 8:33pm ET |
| Benched | TE | Jake Ferguson DAL | Owner | Wed Nov 5 8:33pm ET |
| Started | QB | Marcus Mariota WAS | Owner | Wed Nov 5 8:33pm ET |
| Started | RB | Zach Charbonnet SEA | Owner | Wed Nov 5 8:33pm ET |
| Started | WR | Parker Washington JAX | Owner | Wed Nov 5 8:33pm ET |
Hammer(2QB) - Curt Hammock
| Benched | RB | Tony Pollard TEN | Owner | Tue Nov 4 11:41am ET |
| Started | RB | Emari Demercado ARI | Owner | Tue Nov 4 11:41am ET |
| Benched | QB | Dak Prescott DAL | Owner | Tue Nov 4 11:40am ET |
| Benched | RB | Chase Brown CIN | Owner | Tue Nov 4 11:40am ET |
| Benched | WR | Ja'Marr Chase CIN | Owner | Tue Nov 4 11:40am ET |
| Started | QB | Dillon Gabriel CLE | Owner | Tue Nov 4 11:40am ET |
| Started | RB | Tony Pollard TEN | Owner | Tue Nov 4 11:40am ET |
| Started | WR | Wan'Dale Robinson NYG | Owner | Tue Nov 4 11:40am ET |
Iced Americano 125 - Jack Shea
| Benched | RB | Nick Chubb HOU | Owner | Wed Nov 5 7:24pm ET |
| Benched | WR | CeeDee Lamb DAL | Owner | Wed Nov 5 7:24pm ET |
| Benched | TE | T.J. Hockenson MIN | Owner | Wed Nov 5 7:24pm ET |
| Started | RB | Saquon Barkley PHI | Owner | Wed Nov 5 7:24pm ET |
| Started | RB | Rachaad White TB | Owner | Wed Nov 5 7:24pm ET |
| Started | WR | A.J. Brown PHI | Owner | Wed Nov 5 7:24pm ET |
REPACKDy 2Q - Dale Arnett
| Benched | RB | Aaron Jones MIN | Owner | Wed Nov 5 5:51pm ET |
| Started | QB | Justin Fields NYJ | Owner | Wed Nov 5 5:51pm ET |
Rickety Crickets - Mitchell Lukens
| Benched | WR | Rashid Shaheed SEA | Owner | Tue Nov 4 6:51pm ET |
| Benched | TE | Noah Fant CIN | Owner | Tue Nov 4 6:51pm ET |
| Started | WR | DeVonta Smith PHI | Owner | Tue Nov 4 6:51pm ET |
| Started | TE | Cade Otton TB | Owner | Tue Nov 4 6:51pm ET |
The Tallahassee Pterodactyls -
| Benched | QB | Jayden Daniels WAS | Owner | Tue Nov 4 2:44pm ET |
| Benched | RB | Chuba Hubbard CAR | Owner | Tue Nov 4 2:44pm ET |
| Benched | WR | Alec Pierce IND | Owner | Tue Nov 4 2:44pm ET |
| Started | QB | Jalen Hurts PHI | Owner | Tue Nov 4 2:44pm ET |
| Started | RB | D'Andre Swift CHI | Owner | Tue Nov 4 2:44pm ET |
| Started | WR | Josh Downs IND | Owner | Tue Nov 4 2:44pm ET |
Whack - Matt Rutherford
| Started | WR | Jerry Jeudy CLE | Owner | Wed Nov 5 1:10pm ET |
| Started | WR | Tory Horton SEA | Owner | Wed Nov 5 1:10pm ET |
| Started | QB | Bryce Young CAR | Owner | Wed Nov 5 1:10pm ET |
| Benched | WR | Ricky Pearsall SF | Owner | Wed Nov 5 1:10pm ET |
| Benched | WR | Chimere Dike TEN | Owner | Wed Nov 5 1:10pm ET |
| Benched | QB | Patrick Mahomes KC | Owner | Wed Nov 5 1:10pm ET |
| Started | TE | Theo Johnson NYG | Owner | Tue Nov 4 10:00am ET |
| Started | WR | Ricky Pearsall SF | Owner | Tue Nov 4 10:00am ET |
| Benched | TE | Tucker Kraft GB | Owner | Tue Nov 4 10:00am ET |
| Benched | WR | Roman Wilson PIT | Owner | Tue Nov 4 10:00am ET |
