

| Benched | QB | Jared Goff DET | Owner | Tue Nov 25 9:34pm CT |
| Benched | WR | Jauan Jennings SF | Owner | Tue Nov 25 9:34pm CT |
| Benched | TE | Jake Ferguson DAL | Owner | Tue Nov 25 9:34pm CT |
| Started | QB | Jaxson Dart NYG | Owner | Tue Nov 25 9:34pm CT |
| Started | RB | RJ Harvey DEN | Owner | Tue Nov 25 9:34pm CT |
| Started | WR | Keenan Allen LAC | Owner | Tue Nov 25 9:34pm CT |
| No starting lineup changes performed this week. |
| Benched | WR | Alec Pierce IND | Owner | Thu Nov 27 12:35am CT |
| Benched | WR | Christian Watson GB | Owner | Thu Nov 27 12:35am CT |
| Started | WR | Marvin Harrison Jr. ARI | Owner | Thu Nov 27 12:35am CT |
| Started | WR | Courtland Sutton DEN | Owner | Thu Nov 27 12:35am CT |
| Started | RB | Kenneth Walker III SEA | Owner | Sat Nov 29 10:11pm CT |
| Benched | WR | Drake London ATL | Owner | Sat Nov 29 10:11pm CT |
| Started | WR | Drake London ATL | Owner | Tue Nov 25 12:58pm CT |
| Started | WR | Ja'Marr Chase CIN | Owner | Tue Nov 25 12:58pm CT |
| Started | QB | C.J. Stroud HOU | Owner | Tue Nov 25 12:58pm CT |
| Started | QB | Justin Herbert LAC | Owner | Tue Nov 25 12:58pm CT |
| Benched | WR | Demario Douglas NE | Owner | Tue Nov 25 12:58pm CT |
| Benched | RB | Emanuel Wilson GB | Owner | Tue Nov 25 12:58pm CT |
| Benched | RB | Kenneth Walker III SEA | Owner | Tue Nov 25 12:58pm CT |
| Benched | QB | Mason Rudolph PIT | Owner | Tue Nov 25 12:58pm CT |
| No starting lineup changes performed this week. |
| No starting lineup changes performed this week. |
| Benched | QB | Caleb Williams CHI | Owner | Thu Nov 27 11:15am CT |
| Started | QB | Joe Burrow CIN | Owner | Thu Nov 27 11:15am CT |
| Benched | QB | Aaron Rodgers PIT | Owner | Tue Nov 25 8:33am CT |
| Benched | RB | Josh Jacobs GB | Owner | Tue Nov 25 8:33am CT |
| Started | QB | Jameis Winston NYG | Owner | Tue Nov 25 8:33am CT |
| Started | WR | Luther Burden III CHI | Owner | Tue Nov 25 8:33am CT |
| Started | WR | Brian Thomas Jr. JAX | Owner | Sat Nov 29 9:59pm CT |
| Benched | WR | Troy Franklin DEN | Owner | Sat Nov 29 9:59pm CT |
| Started | TE | Brenton Strange JAX | Owner | Thu Nov 27 7:27am CT |
| Benched | TE | Isaiah Likely BAL | Owner | Thu Nov 27 7:27am CT |
| Started | TE | Isaiah Likely BAL | Owner | Thu Nov 27 7:27am CT |
| Started | WR | Deebo Samuel WAS | Owner | Thu Nov 27 7:27am CT |
| Started | WR | Troy Franklin DEN | Owner | Thu Nov 27 7:27am CT |
| Started | RB | Devon Achane MIA | Owner | Thu Nov 27 7:27am CT |
| Started | QB | Bo Nix DEN | Owner | Thu Nov 27 7:27am CT |
| Benched | TE | Pat Freiermuth PIT | Owner | Thu Nov 27 7:27am CT |
| Benched | WR | Roman Wilson PIT | Owner | Thu Nov 27 7:27am CT |
| Benched | WR | Ricky Pearsall SF | Owner | Thu Nov 27 7:27am CT |
| Benched | WR | Darnell Mooney ATL | Owner | Thu Nov 27 7:27am CT |
| Benched | WR | Jayden Higgins HOU | Owner | Thu Nov 27 7:27am CT |
| Benched | RB | Rachaad White TB | Owner | Thu Nov 27 5:43pm CT |
| Started | RB | Chris Rodriguez Jr. WAS | Owner | Thu Nov 27 5:43pm CT |
| Benched | QB | Brock Purdy SF | Owner | Thu Nov 27 7:25am CT |
| Benched | WR | Tee Higgins CIN | Owner | Thu Nov 27 7:25am CT |
| Benched | TE | Terrance Ferguson LAR | Owner | Thu Nov 27 7:25am CT |
| Started | QB | Josh Allen BUF | Owner | Thu Nov 27 7:25am CT |
| Started | WR | Xavier Worthy KC | Owner | Thu Nov 27 7:25am CT |
| Started | TE | Dalton Kincaid BUF | Owner | Thu Nov 27 7:25am CT |
| No starting lineup changes performed this week. |
| Benched | WR | Jerry Jeudy CLE | Owner | Wed Nov 26 1:12am CT |
| Started | QB | Marcus Mariota WAS | Owner | Wed Nov 26 1:12am CT |