

| Benched | QB | Geno Smith LV | Owner | Wed Nov 26 7:08am CT |
| Started | QB | Justin Herbert LAC | Owner | Wed Nov 26 7:08am CT |
| Benched | WR | Khalil Shakir BUF | Owner | Wed Nov 26 1:17pm CT |
| Benched | D/ST | Cleveland Browns CLE | Owner | Wed Nov 26 1:17pm CT |
| Started | RB | Chris Rodriguez Jr. WAS | Owner | Wed Nov 26 1:17pm CT |
| Started | D/ST | Los Angeles Chargers LAC | Owner | Wed Nov 26 1:17pm CT |
| Benched | TE | AJ Barner SEA | Owner | Thu Nov 27 9:10am CT |
| Started | TE | Theo Johnson NYG | Owner | Thu Nov 27 9:10am CT |
| Started | D/ST | Pittsburgh Steelers PIT | Owner | Thu Nov 27 9:09am CT |
| Benched | RB | Tyjae Spears TEN | Owner | Wed Nov 26 7:50pm CT |
| Benched | WR | Jameson Williams DET | Owner | Wed Nov 26 7:50pm CT |
| Benched | TE | Terrance Ferguson LAR | Owner | Wed Nov 26 7:50pm CT |
| Started | RB | RJ Harvey DEN | Owner | Wed Nov 26 7:50pm CT |
| Started | RB | Bucky Irving TB | Owner | Wed Nov 26 7:50pm CT |
| Started | WR | Ladd McConkey LAC | Owner | Wed Nov 26 7:50pm CT |
| Benched | TE | Brenton Strange JAX | Owner | Sat Nov 29 8:41am CT |
| Started | RB | Kimani Vidal LAC | Owner | Sat Nov 29 8:41am CT |
| Benched | WR | Deebo Samuel WAS | Owner | Wed Nov 26 12:24pm CT |
| Started | TE | Jake Ferguson DAL | Owner | Wed Nov 26 12:24pm CT |
| Benched | WR | Darnell Mooney ATL | Owner | Tue Nov 25 8:13am CT |
| Started | WR | Deebo Samuel WAS | Owner | Tue Nov 25 8:13am CT |
| Started | TE | Brenton Strange JAX | Owner | Tue Nov 25 8:13am CT |
| Benched | WR | Michael Wilson ARI | Owner | Wed Nov 26 9:45pm CT |
| Benched | K | Cam Little JAX | Owner | Wed Nov 26 9:45pm CT |
| Started | WR | Courtland Sutton DEN | Owner | Wed Nov 26 9:45pm CT |
| Started | K | Cameron Dicker LAC | Owner | Wed Nov 26 9:45pm CT |
| Started | WR | Parker Washington JAX | Owner | Sat Nov 29 7:11pm CT |
| Benched | RB | Sean Tucker TB | Owner | Sat Nov 29 7:11pm CT |
| Started | QB | Lamar Jackson BAL | Owner | Thu Nov 27 10:43am CT |
| Benched | QB | Caleb Williams CHI | Owner | Thu Nov 27 10:43am CT |
| Started | TE | Mark Andrews BAL | Owner | Thu Nov 27 10:40am CT |
| Benched | TE | Harold Fannin Jr. CLE | Owner | Thu Nov 27 10:40am CT |
| Started | D/ST | Jacksonville Jaguars JAX | Owner | Thu Nov 27 8:53am CT |
| Started | QB | Caleb Williams CHI | Owner | Wed Nov 26 7:58am CT |
| Benched | QB | Lamar Jackson BAL | Owner | Wed Nov 26 7:58am CT |
| Started | WR | Troy Franklin DEN | Owner | Tue Nov 25 8:12am CT |
| Benched | WR | Tee Higgins CIN | Owner | Tue Nov 25 8:12am CT |
| Benched | RB | Tyrone Tracy Jr. NYG | Owner | Sat Nov 29 8:33pm CT |
| Started | RB | Devin Neal NO | Owner | Sat Nov 29 8:33pm CT |
| Benched | RB | Rachaad White TB | Owner | Tue Nov 25 3:25pm CT |
| Started | RB | Tyrone Tracy Jr. NYG | Owner | Tue Nov 25 3:25pm CT |
| Benched | RB | Zonovan Knight ARI | Owner | Tue Nov 25 4:52pm CT |
| Benched | WR | Jordan Addison MIN | Owner | Tue Nov 25 4:52pm CT |
| Benched | WR | Jerry Jeudy CLE | Owner | Tue Nov 25 4:52pm CT |
| Started | RB | Devon Achane MIA | Owner | Tue Nov 25 4:52pm CT |
| Started | WR | Ja'Marr Chase CIN | Owner | Tue Nov 25 4:52pm CT |
| Started | WR | Jaylen Waddle MIA | Owner | Tue Nov 25 4:52pm CT |
| No starting lineup changes performed this week. |
| No starting lineup changes performed this week. |
| No starting lineup changes performed this week. |
| Benched | RB | Quinshon Judkins CLE | Owner | Thu Nov 27 11:23am CT |
| Started | RB | Josh Jacobs GB | Owner | Thu Nov 27 11:23am CT |
| Benched | QB | Jacoby Brissett ARI | Owner | Wed Nov 26 12:02pm CT |
| Started | QB | Dak Prescott DAL | Owner | Wed Nov 26 12:02pm CT |
| Benched | D/ST | Houston Texans HOU | Owner | Tue Nov 25 12:39pm CT |
| Started | D/ST | Denver Broncos DEN | Owner | Tue Nov 25 12:39pm CT |
| Benched | QB | Dak Prescott DAL | Owner | Tue Nov 25 12:39pm CT |
| Started | QB | Jacoby Brissett ARI | Owner | Tue Nov 25 12:39pm CT |