

| Benched | RB | Kenneth Gainwell PIT | Owner | Sat Nov 29 6:52am ET |
| Started | RB | Kimani Vidal LAC | Owner | Sat Nov 29 6:52am ET |
| Benched | QB | Tua Tagovailoa MIA | Owner | Fri Nov 28 9:03pm ET |
| Started | QB | Baker Mayfield TB | Owner | Fri Nov 28 9:03pm ET |
| Benched | QB | Baker Mayfield TB | Owner | Tue Nov 25 4:45pm ET |
| Benched | WR | Jauan Jennings SF | Owner | Tue Nov 25 4:45pm ET |
| Started | QB | Tua Tagovailoa MIA | Owner | Tue Nov 25 4:45pm ET |
| Started | RB | Devon Achane MIA | Owner | Tue Nov 25 4:45pm ET |
| Benched | WR | Christian Kirk HOU | Owner | Tue Nov 25 7:40pm ET |
| Started | WR | Tre Harris LAC | Owner | Tue Nov 25 7:40pm ET |
| Started | WR | Malik Washington MIA | Owner | Fri Nov 28 9:17pm ET |
| Benched | WR | Alec Pierce IND | Owner | Fri Nov 28 9:17pm ET |
| Started | WR | Alec Pierce IND | Owner | Thu Nov 27 5:09pm ET |
| Started | RB | Zach Charbonnet SEA | Owner | Thu Nov 27 5:09pm ET |
| Benched | WR | Greg Dortch ARI | Owner | Thu Nov 27 5:09pm ET |
| Benched | RB | Jaleel McLaughlin DEN | Owner | Thu Nov 27 5:09pm ET |
| Started | RB | Devin Neal NO | Owner | Thu Nov 27 12:28pm ET |
| Benched | RB | Kyle Monangai CHI | Owner | Thu Nov 27 12:28pm ET |
| Started | WR | Jaylen Waddle MIA | Owner | Tue Nov 25 5:28pm ET |
| Started | WR | Keenan Allen LAC | Owner | Tue Nov 25 5:28pm ET |
| Started | RB | Jaleel McLaughlin DEN | Owner | Tue Nov 25 5:28pm ET |
| Benched | WR | Alec Pierce IND | Owner | Tue Nov 25 5:28pm ET |
| Benched | WR | Demario Douglas NE | Owner | Tue Nov 25 5:28pm ET |
| Benched | RB | Zach Charbonnet SEA | Owner | Tue Nov 25 5:28pm ET |
| Started | WR | Terry McLaurin WAS | Owner | Sun Nov 30 10:18am ET |
| Benched | TE | T.J. Hockenson MIN | Owner | Sun Nov 30 10:18am ET |
| Started | TE | T.J. Hockenson MIN | Owner | Wed Nov 26 10:20am ET |
| Benched | TE | Gunnar Helm TEN | Owner | Wed Nov 26 10:20am ET |
| Started | TE | Gunnar Helm TEN | Owner | Tue Nov 25 1:21pm ET |
| Started | WR | Courtland Sutton DEN | Owner | Tue Nov 25 1:21pm ET |
| Started | RB | Dylan Sampson CLE | Owner | Tue Nov 25 1:21pm ET |
| Benched | TE | T.J. Hockenson MIN | Owner | Tue Nov 25 1:21pm ET |
| Benched | WR | Mack Hollins NE | Owner | Tue Nov 25 1:21pm ET |
| Benched | RB | Bhayshul Tuten JAX | Owner | Tue Nov 25 1:21pm ET |
| Benched | WR | Kayshon Boutte NE | Owner | Tue Nov 25 2:03pm ET |
| Benched | WR | Luther Burden III CHI | Owner | Tue Nov 25 2:03pm ET |
| Benched | WR | Ricky Pearsall SF | Owner | Tue Nov 25 2:03pm ET |
| Started | RB | RJ Harvey DEN | Owner | Tue Nov 25 2:03pm ET |
| Started | WR | Ladd McConkey LAC | Owner | Tue Nov 25 2:03pm ET |
| Started | WR | Parker Washington JAX | Owner | Tue Nov 25 2:03pm ET |
| Benched | RB | Quinshon Judkins CLE | Owner | Sat Nov 29 12:32pm ET |
| Started | RB | Kenneth Walker III SEA | Owner | Sat Nov 29 12:32pm ET |
| Benched | RB | D'Andre Swift CHI | Owner | Wed Nov 26 9:44pm ET |
| Benched | RB | Kenneth Walker III SEA | Owner | Wed Nov 26 9:44pm ET |
| Started | QB | C.J. Stroud HOU | Owner | Wed Nov 26 9:44pm ET |
| Started | RB | Travis Etienne JAX | Owner | Wed Nov 26 9:44pm ET |
| Benched | RB | Tyrone Tracy Jr. NYG | Owner | Wed Nov 26 5:20pm ET |
| Benched | RB | Sean Tucker TB | Owner | Wed Nov 26 5:20pm ET |
| Benched | WR | Darnell Mooney ATL | Owner | Wed Nov 26 5:20pm ET |
| Started | QB | Joe Burrow CIN | Owner | Wed Nov 26 5:20pm ET |
| Started | RB | Bucky Irving TB | Owner | Wed Nov 26 5:20pm ET |
| Started | WR | Deebo Samuel WAS | Owner | Wed Nov 26 5:20pm ET |
| Started | RB | Tony Pollard TEN | Owner | Sat Nov 29 7:14pm ET |
| Benched | RB | Tony Pollard TEN | Owner | Tue Nov 25 6:38pm ET |
| Benched | WR | Andrei Iosivas CIN | Owner | Tue Nov 25 6:38pm ET |
| Benched | TE | Cade Otton TB | Owner | Tue Nov 25 6:38pm ET |
| Started | WR | Ja'Marr Chase CIN | Owner | Tue Nov 25 6:38pm ET |
| Started | TE | Oronde Gadsden II LAC | Owner | Tue Nov 25 6:38pm ET |
| Benched | QB | Bryce Young CAR | Owner | Thu Nov 27 12:01pm ET |
| Benched | WR | Tee Higgins CIN | Owner | Thu Nov 27 12:01pm ET |
| Benched | TE | Juwan Johnson NO | Owner | Thu Nov 27 12:01pm ET |
| Started | QB | Shedeur Sanders CLE | Owner | Thu Nov 27 12:01pm ET |
| Started | WR | Brian Thomas Jr. JAX | Owner | Thu Nov 27 12:01pm ET |
| Started | TE | Kyle Pitts ATL | Owner | Thu Nov 27 12:01pm ET |
| Benched | WR | Jordan Addison MIN | Owner | Thu Nov 27 3:18am ET |
| Started | WR | Marvin Harrison Jr. ARI | Owner | Thu Nov 27 3:18am ET |
| Benched | TE | Mark Andrews BAL | Owner | Wed Nov 26 1:57am ET |
| Started | QB | Marcus Mariota WAS | Owner | Wed Nov 26 1:57am ET |
| Benched | TE | Mason Taylor NYJ | Owner | Sun Nov 30 10:37am ET |
| Started | TE | Evan Engram DEN | Owner | Sun Nov 30 10:37am ET |
| Started | WR | Jerry Jeudy CLE | Owner | Sun Nov 30 10:36am ET |
| Benched | RB | Omarion Hampton LAC | Owner | Sat Nov 29 9:02pm ET |
| Benched | QB | Cam Ward TEN | Owner | Tue Nov 25 6:11pm ET |
| Benched | TE | AJ Barner SEA | Owner | Tue Nov 25 6:11pm ET |
| Started | QB | Justin Herbert LAC | Owner | Tue Nov 25 6:11pm ET |
| Started | RB | Omarion Hampton LAC | Owner | Tue Nov 25 6:11pm ET |
| Benched | RB | Aaron Jones MIN | Owner | Sat Nov 29 8:42pm ET |
| Started | QB | Aaron Rodgers PIT | Owner | Sat Nov 29 8:42pm ET |
| Benched | QB | Joe Flacco CIN | Owner | Tue Nov 25 7:27am ET |
| Benched | RB | Alvin Kamara NO | Owner | Tue Nov 25 7:27am ET |
| Benched | WR | Cedric Tillman CLE | Owner | Tue Nov 25 7:27am ET |
| Started | QB | Jaxson Dart NYG | Owner | Tue Nov 25 7:27am ET |
| Started | RB | Josh Jacobs GB | Owner | Tue Nov 25 7:27am ET |
| Started | WR | Troy Franklin DEN | Owner | Tue Nov 25 7:27am ET |