

| Benched | QB | Jared Goff DET | Owner | Tue Nov 25 3:19pm CT |
| Benched | RB | Emanuel Wilson GB | Owner | Tue Nov 25 3:19pm CT |
| Benched | TE | Brock Wright DET | Owner | Tue Nov 25 3:19pm CT |
| Started | QB | Jacoby Brissett ARI | Owner | Tue Nov 25 3:19pm CT |
| Started | RB | Kenneth Walker III SEA | Owner | Tue Nov 25 3:19pm CT |
| Started | WR | Jauan Jennings SF | Owner | Tue Nov 25 3:19pm CT |
| Benched | QB | Sam Darnold SEA | Owner | Thu Nov 27 6:50am CT |
| Benched | WR | D.K. Metcalf PIT | Owner | Thu Nov 27 6:50am CT |
| Started | QB | Justin Herbert LAC | Owner | Thu Nov 27 6:50am CT |
| Started | RB | Josh Jacobs GB | Owner | Thu Nov 27 6:50am CT |
| Benched | WR | Troy Franklin DEN | Owner | Thu Nov 27 11:05am CT |
| Started | WR | Xavier Worthy KC | Owner | Thu Nov 27 11:05am CT |
| Benched | RB | D'Andre Swift CHI | Owner | Wed Nov 26 4:14pm CT |
| Started | WR | Troy Franklin DEN | Owner | Wed Nov 26 4:14pm CT |
| Benched | QB | Davis Mills HOU | Owner | Tue Nov 25 5:14pm CT |
| Benched | QB | Cam Ward TEN | Owner | Tue Nov 25 5:14pm CT |
| Started | QB | C.J. Stroud HOU | Owner | Tue Nov 25 5:14pm CT |
| Started | QB | Tua Tagovailoa MIA | Owner | Tue Nov 25 5:14pm CT |
| Benched | WR | Tee Higgins CIN | Owner | Wed Nov 26 9:17pm CT |
| Started | WR | Rome Odunze CHI | Owner | Wed Nov 26 9:17pm CT |
| Benched | RB | Devin Singletary NYG | Owner | Tue Nov 25 2:35pm CT |
| Started | WR | Ladd McConkey LAC | Owner | Tue Nov 25 2:35pm CT |
| Benched | RB | Zach Charbonnet SEA | Owner | Thu Nov 27 8:54am CT |
| Benched | TE | Theo Johnson NYG | Owner | Thu Nov 27 8:54am CT |
| Started | QB | Joe Burrow CIN | Owner | Thu Nov 27 8:54am CT |
| Started | RB | Devin Neal NO | Owner | Thu Nov 27 8:54am CT |
| Benched | QB | Jameis Winston NYG | Owner | Wed Nov 26 8:37am CT |
| Benched | WR | Tyrell Shavers BUF | Owner | Wed Nov 26 8:37am CT |
| Benched | TE | Juwan Johnson NO | Owner | Wed Nov 26 8:37am CT |
| Started | WR | Chimere Dike TEN | Owner | Wed Nov 26 8:37am CT |
| Started | WR | Quentin Johnston LAC | Owner | Wed Nov 26 8:37am CT |
| Started | TE | Oronde Gadsden II LAC | Owner | Wed Nov 26 8:37am CT |
| Benched | QB | Mac Jones SF | Owner | Tue Nov 25 7:07pm CT |
| Benched | RB | Alvin Kamara NO | Owner | Tue Nov 25 7:07pm CT |
| Benched | WR | Cooper Kupp SEA | Owner | Tue Nov 25 7:07pm CT |
| Started | WR | Calvin Austin III PIT | Owner | Tue Nov 25 7:07pm CT |
| Started | WR | Ja'Marr Chase CIN | Owner | Tue Nov 25 7:07pm CT |
| Started | WR | Brian Thomas Jr. JAX | Owner | Tue Nov 25 7:07pm CT |
| Benched | RB | Zonovan Knight ARI | Owner | Sun Nov 30 11:26am CT |
| Started | RB | RJ Harvey DEN | Owner | Sun Nov 30 11:26am CT |
| Benched | WR | Greg Dortch ARI | Owner | Sun Nov 30 11:25am CT |
| Started | WR | Kayshon Boutte NE | Owner | Sun Nov 30 11:25am CT |
| Benched | WR | Josh Downs IND | Owner | Sat Nov 29 10:00am CT |
| Started | WR | Jaylen Waddle MIA | Owner | Sat Nov 29 10:00am CT |
| Benched | QB | Joe Flacco CIN | Owner | Tue Nov 25 7:17am CT |
| Started | QB | Bo Nix DEN | Owner | Tue Nov 25 7:17am CT |
| Benched | WR | Jordan Addison MIN | Owner | Wed Nov 26 10:27pm CT |
| Benched | TE | Cade Otton TB | Owner | Wed Nov 26 10:27pm CT |
| Started | RB | Devon Achane MIA | Owner | Wed Nov 26 10:27pm CT |
| Started | WR | Courtland Sutton DEN | Owner | Wed Nov 26 10:27pm CT |
| Benched | QB | Mason Rudolph PIT | Owner | Sun Nov 30 11:58am CT |
| Benched | RB | Sean Tucker TB | Owner | Sun Nov 30 11:58am CT |
| Benched | WR | Ricky Pearsall SF | Owner | Sun Nov 30 11:58am CT |
| Benched | WR | Khalil Shakir BUF | Owner | Sun Nov 30 11:58am CT |
| Started | QB | Shedeur Sanders CLE | Owner | Sun Nov 30 11:58am CT |
| Started | RB | Kenneth Gainwell PIT | Owner | Sun Nov 30 11:58am CT |
| Started | WR | Keenan Allen LAC | Owner | Sun Nov 30 11:58am CT |
| Started | WR | Deebo Samuel WAS | Owner | Sun Nov 30 11:58am CT |
| Benched | RB | Isaac Guerendo SF | Owner | Thu Nov 27 10:57am CT |
| Benched | WR | Roman Wilson PIT | Owner | Thu Nov 27 10:57am CT |
| Benched | TE | Isaiah Likely BAL | Owner | Thu Nov 27 10:57am CT |
| Started | RB | Ollie Gordon II MIA | Owner | Thu Nov 27 10:57am CT |
| Started | WR | Andrei Iosivas CIN | Owner | Thu Nov 27 10:57am CT |
| Started | TE | Brenton Strange JAX | Owner | Thu Nov 27 10:57am CT |