

| Benched | TE | Mark Andrews BAL | Owner | Thu Nov 27 7:34am CT |
| Started | WR | Khalil Shakir BUF | Owner | Thu Nov 27 7:34am CT |
| Benched | QB | Baker Mayfield TB | Owner | Tue Nov 25 6:24am CT |
| Started | QB | Jaxson Dart NYG | Owner | Tue Nov 25 6:24am CT |
| Started | WR | Troy Franklin DEN | Owner | Thu Nov 27 7:19pm CT |
| Started | QB | Josh Allen BUF | Owner | Thu Nov 27 7:19pm CT |
| Benched | RB | D'Andre Swift CHI | Owner | Thu Nov 27 7:19pm CT |
| Benched | QB | Drake Maye NE | Owner | Thu Nov 27 7:19pm CT |
| Started | WR | Jaylen Waddle MIA | Owner | Wed Nov 26 2:09am CT |
| Started | WR | Deebo Samuel WAS | Owner | Wed Nov 26 2:09am CT |
| Started | RB | Devin Neal NO | Owner | Wed Nov 26 2:09am CT |
| Benched | WR | Jakobi Meyers JAX | Owner | Wed Nov 26 2:09am CT |
| Benched | WR | Jordan Addison MIN | Owner | Wed Nov 26 2:09am CT |
| Benched | RB | Alvin Kamara NO | Owner | Wed Nov 26 2:09am CT |
| Benched | WR | Marquise Brown KC | Owner | Tue Nov 25 7:17am CT |
| Benched | TE | Noah Fant CIN | Owner | Tue Nov 25 7:17am CT |
| Started | RB | RJ Harvey DEN | Owner | Tue Nov 25 7:17am CT |
| Started | WR | Keenan Allen LAC | Owner | Tue Nov 25 7:17am CT |
| Benched | WR | Tee Higgins CIN | Owner | Wed Nov 26 2:54pm CT |
| Started | WR | Wan'Dale Robinson NYG | Owner | Wed Nov 26 2:54pm CT |
| Benched | QB | Tyrod Taylor NYJ | Owner | Sat Nov 29 6:49am CT |
| Started | QB | Marcus Mariota WAS | Owner | Sat Nov 29 6:49am CT |
| Benched | WR | Michael Wilson ARI | Owner | Wed Nov 26 6:06pm CT |
| Started | RB | Chase Brown CIN | Owner | Wed Nov 26 6:06pm CT |
| Benched | QB | Davis Mills HOU | Owner | Tue Nov 25 12:54pm CT |
| Benched | TE | AJ Barner SEA | Owner | Tue Nov 25 12:54pm CT |
| Started | QB | Tyrod Taylor NYJ | Owner | Tue Nov 25 12:54pm CT |
| Started | TE | Brenton Strange JAX | Owner | Tue Nov 25 12:54pm CT |
| No starting lineup changes performed this week. |
| Benched | TE | Dalton Kincaid BUF | Owner | Fri Nov 28 11:39am CT |
| Started | TE | Colby Parkinson LAR | Owner | Fri Nov 28 11:39am CT |
| Benched | WR | Jameson Williams DET | Owner | Wed Nov 26 11:44am CT |
| Benched | TE | Colby Parkinson LAR | Owner | Wed Nov 26 11:44am CT |
| Started | RB | Devon Achane MIA | Owner | Wed Nov 26 11:44am CT |
| Started | TE | Dalton Kincaid BUF | Owner | Wed Nov 26 11:44am CT |
| Benched | WR | Tez Johnson TB | Owner | Thu Nov 27 12:58am CT |
| Benched | WR | Ricky Pearsall SF | Owner | Thu Nov 27 12:58am CT |
| Started | WR | Darnell Mooney ATL | Owner | Thu Nov 27 12:58am CT |
| Started | WR | Xavier Worthy KC | Owner | Thu Nov 27 12:58am CT |
| Benched | WR | Darius Slayton NYG | Owner | Wed Nov 26 7:17pm CT |
| Started | WR | Tez Johnson TB | Owner | Wed Nov 26 7:17pm CT |
| Benched | QB | Shedeur Sanders CLE | Owner | Wed Nov 26 6:44pm CT |
| Benched | WR | Alec Pierce IND | Owner | Wed Nov 26 6:44pm CT |
| Started | QB | Bo Nix DEN | Owner | Wed Nov 26 6:44pm CT |
| Started | WR | Ja'Marr Chase CIN | Owner | Wed Nov 26 6:44pm CT |
| Benched | QB | Brock Purdy SF | Owner | Sat Nov 29 11:19am CT |
| Started | QB | Aaron Rodgers PIT | Owner | Sat Nov 29 11:19am CT |
| Benched | WR | Michael Pittman Jr. IND | Owner | Fri Nov 28 8:13am CT |
| Started | WR | Chimere Dike TEN | Owner | Fri Nov 28 8:13am CT |
| Benched | RB | Aaron Jones MIN | Owner | Tue Nov 25 8:00am CT |
| Started | RB | Kenneth Gainwell PIT | Owner | Tue Nov 25 8:00am CT |
| Benched | RB | Emanuel Wilson GB | Owner | Wed Nov 26 5:52pm CT |
| Started | RB | Josh Jacobs GB | Owner | Wed Nov 26 5:52pm CT |
| Benched | QB | Joe Flacco CIN | Owner | Wed Nov 26 1:07am CT |
| Benched | WR | Cedric Tillman CLE | Owner | Wed Nov 26 1:07am CT |
| Benched | D/ST | Cleveland Browns CLE | Owner | Wed Nov 26 1:07am CT |
| Started | QB | Tua Tagovailoa MIA | Owner | Wed Nov 26 1:07am CT |
| Started | WR | Ladd McConkey LAC | Owner | Wed Nov 26 1:07am CT |
| Started | D/ST | Denver Broncos DEN | Owner | Wed Nov 26 1:07am CT |