Guest of the League
Lineup Changes
Black - Chuck Faust
| Benched | RB | Quinshon Judkins CLE | Owner | Thu Nov 27 10:02am ET |
| Started | WR | Khalil Shakir BUF | Owner | Thu Nov 27 10:02am ET |
| Started | K | Jason Myers SEA | Owner | Thu Nov 27 12:23am ET |
| Benched | WR | D.K. Metcalf PIT | Owner | Wed Nov 26 8:35am ET |
| Started | WR | Ladd McConkey LAC | Owner | Wed Nov 26 8:35am ET |
Nixty Nine - Lance Drain
| Benched | QB | Sam Darnold SEA | Owner | Thu Nov 27 12:00pm ET |
| Benched | K | Blake Grupe NO | Owner | Thu Nov 27 12:00pm ET |
| Started | QB | Bo Nix DEN | Owner | Thu Nov 27 12:00pm ET |
| Started | K | Daniel Carlson LV | Owner | Thu Nov 27 12:00pm ET |
Press Coverage - Luke O'Reilly
| Benched | QB | J.J. McCarthy MIN | Owner | Tue Nov 25 12:01pm ET |
| Benched | RB | Chuba Hubbard CAR | Owner | Tue Nov 25 12:01pm ET |
| Benched | WR | Marquise Brown KC | Owner | Tue Nov 25 12:01pm ET |
| Started | QB | Justin Herbert LAC | Owner | Tue Nov 25 12:01pm ET |
| Started | RB | Devon Achane MIA | Owner | Tue Nov 25 12:01pm ET |
| Started | WR | Brian Thomas Jr. JAX | Owner | Tue Nov 25 12:01pm ET |
Prison Mike -
| Benched | RB | Rachaad White TB | Owner | Tue Nov 25 4:21pm ET |
| Started | RB | Devin Neal NO | Owner | Tue Nov 25 4:21pm ET |
| Benched | QB | Joe Flacco CIN | Owner | Tue Nov 25 9:07am ET |
| Benched | WR | Tee Higgins CIN | Owner | Tue Nov 25 9:07am ET |
| Benched | TE | AJ Barner SEA | Owner | Tue Nov 25 9:07am ET |
| Started | QB | Jacoby Brissett ARI | Owner | Tue Nov 25 9:07am ET |
| Started | WR | Marvin Harrison Jr. ARI | Owner | Tue Nov 25 9:07am ET |
| Started | TE | Oronde Gadsden II LAC | Owner | Tue Nov 25 9:07am ET |
Pullinfront - Brent Campbell
| Benched | WR | Josh Downs IND | Owner | Tue Nov 25 3:01pm ET |
| Started | WR | Courtland Sutton DEN | Owner | Tue Nov 25 3:01pm ET |
Sorcerers EG - John Measner
| No starting lineup changes performed this week. |
SquadMe250Mike - Ferguson
| Benched | RB | Alvin Kamara NO | Owner | Tue Nov 25 6:28pm ET |
| Started | WR | Deebo Samuel WAS | Owner | Tue Nov 25 6:28pm ET |
The Coronator -
| Benched | WR | CeeDee Lamb DAL | Owner | Wed Nov 26 3:32pm ET |
| Started | WR | Rashee Rice KC | Owner | Wed Nov 26 3:32pm ET |
| Benched | WR | Rashee Rice KC | Owner | Wed Nov 26 3:32pm ET |
| Started | WR | Ja'Marr Chase CIN | Owner | Wed Nov 26 3:32pm ET |
| Benched | D/ST | Baltimore Ravens BAL | Owner | Wed Nov 26 3:32pm ET |
| Started | D/ST | Los Angeles Rams LAR | Owner | Wed Nov 26 3:32pm ET |
The Evil Empire - Christopher Zoufaly
| Benched | WR | Greg Dortch ARI | Owner | Thu Nov 27 12:28pm ET |
| Started | WR | Xavier Worthy KC | Owner | Thu Nov 27 12:28pm ET |
| Benched | QB | Tyler Shough NO | Owner | Wed Nov 26 8:53pm ET |
| Started | QB | Jaxson Dart NYG | Owner | Wed Nov 26 8:53pm ET |
| Benched | WR | Tre Tucker LV | Owner | Wed Nov 26 12:10pm ET |
| Started | RB | Josh Jacobs GB | Owner | Wed Nov 26 12:10pm ET |
| Benched | TE | Harold Fannin Jr. CLE | Owner | Wed Nov 26 12:10pm ET |
| Started | TE | Dalton Kincaid BUF | Owner | Wed Nov 26 12:10pm ET |
The O-Dogs - Jamie Orland
| Benched | D/ST | Buffalo Bills BUF | Owner | Wed Nov 26 1:56pm ET |
| Started | D/ST | Philadelphia Eagles PHI | Owner | Wed Nov 26 1:56pm ET |
Unknown - Craig Nelson
| Started | D/ST | Arizona Cardinals ARI | Owner | Thu Nov 27 1:16am ET |
| Benched | WR | Chris Olave NO | Owner | Tue Nov 25 2:39pm ET |
| Started | WR | Jaylen Waddle MIA | Owner | Tue Nov 25 2:39pm ET |
| Benched | WR | Emeka Egbuka TB | Owner | Tue Nov 25 2:39pm ET |
| Started | WR | Davante Adams LAR | Owner | Tue Nov 25 2:39pm ET |
Wreckitralph - Todd Yost
| Benched | QB | Baker Mayfield TB | Owner | Wed Nov 26 10:18pm ET |
| Started | QB | Tua Tagovailoa MIA | Owner | Wed Nov 26 10:18pm ET |
| Benched | RB | Devin Singletary NYG | Owner | Wed Nov 26 10:17pm ET |
| Benched | WR | Alec Pierce IND | Owner | Wed Nov 26 10:17pm ET |
| Started | RB | RJ Harvey DEN | Owner | Wed Nov 26 10:17pm ET |
| Started | WR | Keenan Allen LAC | Owner | Wed Nov 26 10:17pm ET |
