San Francisco 49ers wide receiver Brandon Aiyuk (knee) was spotted doing some running on the side during Wednesday's practice. It sounds like Aiyuk is continuing to make progress, but is still going to be sidelined for a few weeks. He's currently on the physically unable to perform list through Week 4. There haven't been many updates on his status lately. The assumption is that Aiyuk should be ready to play around Week 5 or 6, but there should be a better timetable closer to that date. Aiyuk should be stashed in most 12-team formats as he'll likely be a focal point of the offense once he's ready to play.

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Atlanta Falcons wide receiver Darnell Mooney (shoulder) was a limited participant during Wednesday's practice session. Mooney missed most of training camp and Week 1 due to a shoulder issue. He made his season debut last week, but was mostly quiet on the field. He hauled in two of his four targets for 20 yards in the victory over the Minnesota Vikings. The fact he was a limited participant on Wednesday could be the Falcons being cautious. Fantasy managers should check back on Thursday and Friday to see if his status changes at all ahead of the Week 3 matchup against the Carolina Panthers. The veteran wideout should be rostered in most 12-team formats despite a slow start.

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Jacksonville Jaguars running back Bhayshul Tuten (shoulder) was limited during Wednesday's practice session. Fantasy managers shouldn't be too worried as Tuten still has plenty of time to get ready before the Week 3 matchup against the Houston Texans. Without Tank Bigsby in the picture, Tuten was able to make a big splash last week. He rushed eight times for 42 yards while adding two receptions for 32 yards and a touchdown in the loss to the Cincinnati Bengals. Sadly, Tuten is going to have his value limited as the backup to Travis Etienne Jr. right now. Despite that, Tuten should continue to see his role rise if he plays well. He should be rostered in most 12-team formats at the moment even as the backup.

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Minnesota Vikings running back Jordan Mason is expected to be the main focus in the running game over the next few games. Recently, head coach Kevin O'Connell expressed confidence that Mason has bellcow potential. They expect Mason to handle a significant rushing workload while Aaron Jones (hamstring) is sidelined. The Vikings believe Mason is a multi-faceted player that can do just about anything on the football field. So far this season, Mason has rushed 24 times for 98 yards over the first two games of the season. There's not much competition behind Mason in the backfield right now. He should see all the carries he can handle, which should at least offer RB2 value for their upcoming matchup against the Cincinnati Bengals.

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Denver Broncos quarterback Bo Nix said that second-year wide receiver Troy Franklin is "starting to develop into the player everyone knows he can become." Franklin, who was teammates with Nix at Oregon, had a breakout game in the Week 2 loss to the Indianapolis Colts, catching eight of his nine targets for 89 yards and a touchdown. The 22-year-old wideout currently leads the Broncos in targets (15), catches (12), and receiving yards (133) through the first two games in 2025. Franklin probably won't take over WR1 duties from Courtland Sutton, but a second-year breakout could very well be in the cards for him, especially because of his strong chemistry with Nix. His primary competition for weekly targets will come from Marvin Mims Jr., who is more of a big-play deep threat than one who will be consistently peppered with targets. If you need WR help early on, Franklin is definitely worth a waiver-wire pickup.

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Los Angeles Rams WR Davante Adams (non-injury) was given the day off for rest and did not participate in practice Wednesday, Sept. 17.

Fantasy Spin: Adams has made an immediate impact for the Rams, logging a team-high 21 targets through two games. Perhaps more importantly, both he and Puka Nacua are putting up strong numbers simultaneously, so there is reason to believe that Adams can continue to have success. At the very least, Adams is a WR3 with upside.

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Denver Broncos rookie second-round running back RJ Harvey is "an important piece of what we're doing," according to head coach Sean Payton. That may be true, and Harvey could see his role grow as the season progresses, but right now, his fantasy value is capped with J.K. Dobbins serving as the RB1 in Denver. Harvey was out-touched 15-6 by Harvey in the Week 2 loss to the Indianapolis Colts and finished with only five carries for eight yards (1.6 yards per tote) while adding one catch for a nice 16-yard gain. In the season-opening win over the Tennessee Titans, the UCF product had six carries for 70 yards and one reception for a loss of a yard. The 24-year-old is slippery with plenty of big-play potential, but right now, he's merely an RB3/flex for fantasy managers with a low floor and ceiling. Harvey and the Broncos also have a difficult upcoming divisional tilt against the 2-0 Los Angeles Chargers on the road this Sunday.

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Los Angeles Rams OG Steve Avila (undisclosed), DL Braden Fiske (undisclosed), WR Davante Adams (non-injury) and OT Rob Havenstein (non-injury) did not practice Wednesday, Sept. 17. TE Colby Parkinson (shoulder) was a limited participant.

From TheHuddle

Arizona Cardinals quarterback Kyler Murray didn't exactly ease fantasy managers' concerns regarding second-year wide receiver Marvin Harrison Jr. when talking to the media on Wednesday. "There's only one ball. We've been playing this game for a long time. Some days he's gonna get 10, and some days he might get 3. You never know," Murray said when asked if he felt Harrison should have more targets through two weeks. Harrison and Murray supposedly improved their chemistry in the offseason, but through two games, we have yet to see it. The 23-year-old former fourth overall pick is tied for 49th among WRs with 11 targets through two games and has caught seven of them for 98 yards and a touchdown. It might take Harrison a bit more time to reach his true potential, but fantasy managers will be hoping he'll rebound in a divisional matchup this Sunday against the San Francisco 49ers.

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Green Bay Packers running back Josh Jacobs (ankle) is dealing with an ankle injury and was listed as a limited participant on the first injury report of Week 3 on Wednesday. It's probably just a bit of rest for the veteran RB early in the week, but it's something worth watching the next few days for fantasy managers. The 27-year-old has been Green Bay's workhorse back through two weeks, as expected, handling 42 carries for 150 yards (3.6 yards per carry) and two touchdowns on the ground, adding one catch for four yards. The Packers will have more than a week of rest going into a Week 3 tilt against the Cleveland Browns, so we'd expect Jacobs to return to practice later this week and play on Sunday. Jacobs should be considered a must-start RB in fantasy if he's active. If he's out or limited, both Chris Brooks and Emanuel Wilson would likely share backfield touches.

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San Francisco 49ers DE Nick Bosa (non-injury), OT Spencer Burford (knee), DE Yetur Gross-Matos (knee), WR Jauan Jennings (ankle, shoulder), FB Kyle Juszczyk (concussion), RB Christian McCaffrey (calf), S Siran Neal (concussion) and OT Trent Williams (knee) did not participate in practice Wednesday, Sept. 17. QB Brock Purdy (shoulder, toe) was limited during practice, while RB Jordan James (finger) fully participated in practice.

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The Washington Commanders are expected to "err on the side of caution" with quarterback Jayden Daniels (knee) as he battles a knee sprain that he suffered in the Week 2 loss to the Green Bay Packers last Thursday night, according to Ian Rapoport of NFL Network. Daniels will not practice this week until at least Friday, and if there is any doubt at all by then, the team is expected to keep him out in Week 3 on Sunday against the Las Vegas Raiders. In a best-case scenario, it seems like Daniels will be questionable this weekend. The Commanders had backup Marcus Mariota meet with the media on Wednesday, an early sign that they are leaning toward starting him under center against the Raiders. Fantasy managers should not plan on having Daniels available in Week 3. If he's out, Washington could lean on the ground game more with rookie Jacory Croskey-Merritt and Chris Rodriguez Jr., who will be making his 2025 debut after Austin Ekeler's season-ending Achilles injury in Week 2.

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San Francisco 49ers RB Christian McCaffrey (calf) did not participate in practice Wednesday, Sept. 17.

Fantasy Spin: McCaffrey probably will not practice much this season but is on track to play in Week 3. He has been productive in both the running and passing game over the first two weeks and is a must-start option in all fantasy leagues.

From TheHuddle

Kansas City Chiefs DE Mike Danna (quadriceps) and CB Kristian Fulton (ankle) did not participate in practice Wednesday, Sept. 17. WR Jalen Royals (knee), WR Xavier Worthy (shoulder) and OT Josh Simmons (illness) were limited during practice. WR Hollywood Brown (ankle), DE Ashton Gillotte (elbow), QB Patrick Mahomes (wrist), DE Charles Omenihu (hand), OT Jawaan Taylor (ankle, knee) and LB Drue Tranquill (knee) fully participated in practice.

From TheHuddle

Kansas City Chiefs QB Patrick Mahomes (wrist) fully participated in practice Wednesday, Sept. 17.

Fantasy Spin: Mahomes is off to a pretty quiet start to the season with 445 passing yards and two passing touchdowns but has been able to help his fantasy value by rushing for two touchdowns and having at least 55 rushing yards in each of the first two games. He may get one of his receivers back this week and can be a starting option in all fantasy leagues.

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Las Vegas Raiders tight end Brock Bowers (knee) injured his knee in the season-opening win over the New England Patriots and was questionable to face the Los Angeles Chargers on Monday Night Football in Week 2. Bowers ended up playing, handling 77 percent of the offensive snaps while catching five of his eight targets for a disappointing 38 yards in a 20-9 loss. As long as the 22-year-old former first-rounder doesn't have a setback with his knee at practice later this week, he should be ready to roll for a nice Week 3 matchup against the Washington Commanders. Washington has allowed the fourth-most half-PPR points to opposing tight ends through two weeks, so Bowers could be primed for a big day this Sunday. He is already one of the top TEs in the NFL after posting a 112-1,194-5 line on 153 targets in 17 games in his rookie year in 2024.

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Seattle Seahawks running back Zach Charbonnet (foot) is dealing with a foot injury and picked up a DNP tag at the first practice of the week on Wednesday, according to Michael-Shawn Dugar of The Athletic. It's not ideal for Charbonnet to miss the first practice of the week, but it's unclear if his injury is serious enough to sideline him in the Week 3 game this Sunday against the New Orleans Saints. The 24-year-old is going to continue to have an elevated role in 2025 as Seattle looks to keep the oft-injured Kenneth Walker III healthy, which makes him a flex option for fantasy managers every week. Through two weeks, Charbonnet has 27 carries for 57 yards (2.1 yards per carry) and one touchdown. He hasn't had a single pass-game target. Walker would see a boost in workload this Sunday if Charb cannot play, while George Holani would be elevated to the RB2 role.

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Miami Dolphins kicker Riley Patterson will continue to fill in for Jason Sanders (hip) for a third straight week when his team visits the Bills on Thursday Night Football. Patterson is on the Dolphins' practice squad but has been promoted for each of Miami's two games this season. He has converted both of his field-goal attempts and all three of his extra-point tries so far this season. However, he's only the K28 in RotoBaller's Week 3 rankings, since the Dolphins' offense has been so off this year and is in a tough spot to get back on track against the defending division champs in Buffalo. If Patterson continues to produce, he could earn a full-time role with Miami or another team later this season, but for now, he's not an elite option for standard leagues.

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Denver Broncos TE Evan Engram (back), LB Dre Greenlaw (quadriceps) and LB Justin Strnad (foot) did not participate in practice Wednesday, Sept. 17. S Talanoa Hufanga (chest) was limited during practice. TE Nate Adkins (ankle), LB Nik Bonitto (wrist) and LB Alex Singleton (thumb) fully participated in practice.

From TheHuddle

Miami Dolphins tight end Tanner Conner has been splitting time almost evenly with starter Julian Hill, as the duo works to replace Darren Waller (hip), who will miss his third straight game when the Dolphins take on the Bills on Thursday Night Football. While Hill is still without a target, Conner had four targets in Week 1, making two catches for 20 yards. He did not have a catch or a target in Week 2, though, as the Dolphins offense continues to not utilize either tight end in a pass-catching role. Conner is the TE43 in the RotoBaller rankings for this week, so you can probably do better than playing him in all formats.

From RotoBaller