Minnesota Vikings wide receiver Jalen Nailor (back) was a limited participant during Wednesday's practice session. Nailor gave fantasy managers a strong performance last weekend with a two-touchdown game against the Dallas Cowboys. The 26-year-old must have picked up a minor back issue during that victory, however. Nailor has seen a bigger role over the last two weeks with quarterback J.J. McCarthy back under center. It seems that the two of them are building some decent chemistry together. Nailor makes for a possible deep-league flex option, assuming he's able to suit up for the upcoming matchup against the New York Giants. If not, rookie Tai Felton could see more action on the field, but he wouldn't be a recommended streaming option. The absence of Nailor would likely just mean more targets for Justin Jefferson and Jordan Addison.

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Tennessee Titans wide receiver Van Jefferson (back) was a non-participant during Wednesday's practice. This comes after Jefferson was forced to exit early during Sunday's loss to the San Francisco 49ers. Jefferson will get two more chances to practice ahead of the Week 16 matchup against the Kansas City Chiefs. The 29-year-old has been a non-factor mostly all year, but he's had two or fewer receptions in three of his last four games. The absence of Jefferson would likely mean slightly larger roles for rookies Elic Ayomanor and Chimere Dike. Also, James Proche II could see more time on the field, but he's not someone worth targeting in fantasy football at this time of year.

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Cincinnati Bengals tight end Noah Fant (ankle) was a non-participant during Wednesday's practice session. Fant was forced to leave during the first half of Sunday's loss to the Baltimore Ravens. Fant is now trending in the wrong direction for this weekend's game against the Miami Dolphins due to a right-ankle issue. Fant hasn't been much help to fantasy managers recently anyway. He has been held to one reception or fewer in each of his last four games. The absence of Fant would mean a larger workload for Mike Gesicki, while Tanner Hudson would serve as the No. 2. Gesicki will be an intriguing streaming option with an expanded role against the Dolphins in Week 16.

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Denver Broncos running back Jaleel McLaughlin has been buried on Denver's RB depth chart for most of the year. He's been active in only five games in 2025, handling 19 carries for 69 yards (career-low 3.6 yards per carry) while catching three of his four targets for 10 yards. The 25-year-old played only nine offensive snaps (13% snap share) in Sunday's victory over the Green Bay Packers, carrying the ball two times for four yards. McLaughlin has been on the fantasy watch list going into Week 16, though, with rookie RJ Harvey leaving the Week 15 contest late due to a rib injury. Harvey returned to a full practice on Wednesday and is expected to be fine for Week 16 this Sunday against the visiting Jacksonville Jaguars, but his injury is a reminder that McLaughlin would be the likely next man up as Denver's lead back if anything were to happen to Harvey. McLaughlin is handcuff-worthy in deeper fantasy formats, and he's rostered in just 2% of Yahoo leagues.

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Jacksonville Jaguars rookie running back Bhayshul Tuten (finger) was a non-participant at Wednesday's practice session. Tuten suffered a right-finger injury during Sunday's win over the New York Jets. The rookie running back is likely going to require surgery to repair his right-finger injury. If that happens, Tuten is expected to miss multiple weeks of action and possibly the final three weeks of the regular season. His absence would likely mean a larger role for Travis Etienne Jr. in the backfield. Rookie LeQuint Allen Jr. will also be asked to step up as the backup to Etienne. Allen has been quiet with 81 yards on 18 attempts this season as the third-string back. There's a chance he offers deep-league fantasy value if Tuten is unable to play against the Denver Broncos in Week 16.

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Philadelphia Eagles wide receiver A.J. Brown has made his voice heard about his frustration in Philly. Brown has been visibly frustrated with the team's inability to get him the ball this season. The organization could decide to move on from the disgruntled wideout this offseason. The 28-year-old is in his prime and could get the Eagles a haul in return. The Eagles have had success, even when Brown isn't heavily involved. Brown saw only two targets during last week's blowout win over the Las Vegas Raiders, but he caught them both for 41 yards and a touchdown, his fourth score in the last four games. The Eagles could move Brown and upgrade other areas of their roster with the freed-up salary cap space. It's certainly something the organization needs to at least consider this offseason.

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Cincinnati Bengals quarterback Joe Burrow has made headlines with some of his recent press conferences, and Wednesday's session with the media was no exception. When asked if there was any world he could imagine where he was not the starting quarterback of the Bengals in 2026, he answered clearly and definitively, "I couldn't see that. No." However, when asked if he's ever thought about it throughout his career, his answer rang more ominous, stating, "You think about a lot of things," and wrapping up the exchange with, "Crazy things can happen." As the team's franchise quarterback, all of Burrow's words are going to be carefully dissected, and the recent line of questioning he's faced has certainly induced noteworthy soundbites. Still, for fantasy managers who managed to escape a lackluster Week 15 performance against the Ravens, Burrow faces a favorable Dolphins defense in Week 16 and should be able to bounce back for the fantasy semifinals, especially if Tee Higgins (concussion), who was limited on Wednesday, is able to return after a one-game absence.

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Chicago Bears wide receiver DJ Moore is coming off a 69-yard, two-touchdown performance against the Browns that was good enough to make him a top-five fantasy wide receiver for the third time in the last seven weeks. The Bears now head into a Week 16 divisional matchup with the Packers, and with the rest of their receiving corps at less than full health, Moore could be in line for another impactful fantasy outing. Neither Rome Odunze (foot) nor Luther Burden III (ankle) has been able to participate in the first two practices of the week, while Cole Kmet (ankle, knee) was limited both Monday and Tuesday. Moore had his worst outing of the season in Week 14 against this same Packers defense, finishing the game with negative receiving yardage, but he heads into the Saturday rematch as RotoBaller's WR 39 for the week and should rise higher if Odunze and Burden are unable to suit up.

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Miami Dolphins tight end Darren Waller (rest, knee) was limited on Wednesday after taking a scary-looking hit to the knee during Monday night's loss to the Steelers. Waller has played in each of the last three games since missing five weeks with a pectoral injury, and began each of those weeks with a limited/rest practice. The additional designation of the knee injury is new for Week 16 and will need to be monitored, though he seemed to finish the game without limitation, catching two late touchdown passes. Waller will be one of the most difficult start/sit decisions for fantasy semifinals. The Dolphins face a historically bad Bengals defense, but the Wednesday news that quarterback Tua Tagovailoa will be benched in favor of 7th-round rookie Quinn Ewers casts a considerable shadow over Miami's offensive outlook. Waller is RotoBaller's TE8 for Week 16, but the new injury designation may be the deciding factor for many fantasy managers to pivot to another streamer.

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Tampa Bay Buccaneers wide receiver Mike Evans (collarbone) was limited on Wednesday after returning from a six-game absence to play and dominate in the team's Week 15 loss to the Falcons. After missing nearly two months with a broken collarbone, Evans caught six of 10 targets on Thursday night for 132 yards. While he played only 38 of 69 total offensive snaps, his 28 routes run were second-most on the team behind Chris Godwin, while his 4.71 yards per route run trailed only Puka Nacua and Luther Burden III across the league. At 32 years old, with a serious list of injuries sustained this season alone, the limited practice to begin the week is not unexpected, but fantasy managers will still need to monitor his status before a pivotal Week 16 matchup with the Panthers.

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Los Angeles Chargers wide receiver Quentin Johnston (groin) was limited on Wednesday by the same groin injury that held him out of Week 15's win over the Chiefs. Johnston was a late addition to last week's injury report, logging a limited practice on Friday before missing his second game of the season. After a red-hot start to the year, Johnston has struggled with consistency, making him one of the more difficult start/sit decisions for most of the fantasy season. If he is able to ramp up his practice participation, he remains in play as a desperation start for the fantasy semifinals, as the Chargers face a Cowboys defense that ranks dead last in points surrendered above expectation to the wide receiver position.

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Los Angeles Rams wide receiver Davante Adams (hamstring) did not practice all week and has been listed as doubtful to play on Thursday night against the division-rival Seattle Seahawks in Week 16, according to John Boyle of Seahawks.com. Adams aggravated a hamstring issue he's been battling for weeks now in Sunday's win over the Detroit Lions, and on a short week, he's unlikely to be able to go. The 32-year-old veteran wideout is a big loss for a high-scoring Rams offense and for fantasy managers, as he currently leads the league with 14 touchdown receptions in 14 games played. It will be Adams' first missed game of 2025, with his next chance to return coming in Week 17 against the Atlanta Falcons on Monday Night Football on Dec. 29. With Adams likely out on Thursday, Tutu Atwell, Jordan Whittington, and Konata Mumpfield will look to soak up targets behind top wideout Puka Nacua against a tough Seahawks defense.

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Dallas Cowboys running back Javonte Williams (neck) was listed as a limited participant due to a neck injury on Wednesday, according to Jon Machota of The Athletic. Williams suffered a neck/shoulder injury in the Sunday night loss to the Minnesota Vikings shortly after a touchdown plunge on the team's first drive of the game in the first quarter. The 25-year-old sat out the rest of the first half, but he eventually returned in the second half and finished with 15 carries for 91 yards and the one touchdown while playing only 28% of the snaps. Williams should be able to play this weekend against the visiting Los Angeles Chargers, but fantasy managers will want to continue monitoring his status leading up to Sunday's game. If Williams is limited at all or out, Malik Davis, who had 10 touches for 37 yards and a touchdown in Week 15, would become Dallas' lead back.

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Denver Broncos rookie wide receiver Pat Bryant (hamstring) was a full participant in Wednesday's practice, according to Zac Stevens of DNVR Sports. A hamstring issue kept Bryant from playing in the Week 15 win over the Green Bay Packers. Head coach Sean Payton said the 23-year-old could have played if it were a playoff game. Now that Bryant is back to practicing in full, he should be active this Sunday versus the visiting Jacksonville Jaguars, barring a setback in the next two days. Bryant's impending return is bad news for second-year wideout Troy Franklin, who caught all six of his targets for 85 yards and a touchdown against Green Bay. Before his hamstring injury, Bryant was seeing more involvement in Denver's passing attack, catching 12 of 17 targets for 156 yards in Weeks 11, 13, and 14. If he's back this weekend, Bryant profiles as a WR4/flex option in deeper fantasy formats. He has just one trip to the end zone in his first 13 NFL contests.

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Green Bay Packers wide receiver Jayden Reed (personal) was not present at the team's practice on Wednesday due to a personal matter, according to the team's official website. Reed should be back at practice on Thursday and play on Saturday against the division-rival Chicago Bears in Week 16. The 25-year-old has played in just four games in 2025 due to a fractured foot and broken collarbone. Since returning in Week 14, Reed has nine catches on 10 targets for 86 yards while also having two rushing attempts for 22 yards. Quarterback Jordan Love continues to spread the ball around to Green Bay's many receiving options, but Reed will remain an integral part of the offense in the final three weeks of the season. It looks like fellow wideout Christian Watson (chest) will play on Saturday, but Reed will still have high-end WR3/flex value for fantasy managers against the Bears.

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New Orleans Saints running back Alvin Kamara (knee, ankle) was listed as a non-participant in the first practice of the week on Wednesday, according to the team's official website. Kamara still has not practiced since spraining his MCL in Week 12. Additionally, rookie Devin Neal injured his hamstring in the Week 15 win over the Carolina Panthers and has already been ruled out for Sunday's game against the visiting New York Jets. It means that if Kamara doesn't make rapid progress over the next two days, Audric Estime and Evan Hull figure to split backfield duties for the Saints in Week 16. The fact that the Saints ruled Neal out so early in the week could be a sign that Kamara is nearing a return, but he will need to return to practice in the next few days. Estime handled 36% of the snaps to Hull's 32% last week and had three carries for 11 yards and three catches for 39 yards. Estime is the better waiver-wire pickup with Neal injured, but at best, he'll profile as a low-upside RB3/flex in fantasy this weekend if Kamara misses another game.

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Baltimore Ravens head coach John Harbaugh said that quarterback Lamar Jackson (illness) was kept at home on Wednesday due to flu-like symptoms, according to Cordell Woodland of 105.7 The Fan. Jackson has been a regular DNP in Wednesday practices this year, but mainly due to nagging lower-body injuries. This week, he's under the weather. The 28-year-old two-time MVP has been held out of practice early in the week in recent weeks with an ankle injury, but he said last week that he has been improving. He should be ready to go by Sunday night for a showdown against the New England Patriots, where he'll be more of a low-end QB1 in fantasy football. Jackson looked a little more like himself in last week's shutout win over the Bengals, but he completed only eight passes and ran the ball twice. He hasn't thrown for over 300 yards at all in 2025 and has had more than one touchdown pass just once in his last six contests. On top of that, Jackson only has two rushing touchdowns this season.

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Buffalo Bills tight end Dalton Kincaid (knee) was listed as a non-participant in Wednesday's practice session, according to the team. Kincaid played in each of the past two games after dealing with knee and hamstring injuries in prior weeks, but he will begin this week with a DNP. The Bills could be managing his workload during the practice week to ensure he is ready to go on gameday. Fantasy managers will want to monitor his status in practice on Thursday and Friday in case he suffered a setback that would cause him to miss some time. Injuries seem to be a lingering issue for the 26-year-old tight end, as he played only 36% of the snaps in the Week 15 win against the New England Patriots, catching three of four targets for 34 yards. If Kincaid is unable to play on Sunday versus the Cleveland Browns, Dawson Knox would be in line for an expanded receiving role and could continue his recent stretch of production.

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Dallas Cowboys wide receiver CeeDee Lamb (illness) was under the weather on Wednesday and did not practice, according to Clarence Hill Jr. of All City Dallas. Lamb isn't feeling well to begin the practice week, but he should be just fine for Sunday's Week 16 game against the visiting Los Angeles Chargers, where he'll remain a must-start fantasy football receiver. The 26-year-old four-time Pro Bowler hasn't been quite as good as teammate George Pickens in 2025, but he's been a top-10 fantasy wideout in terms of half-PPR points per game (14.7). In his 10 games played, Lamb has 63 receptions on 99 targets for 976 yards and three touchdowns. He's had over 100 receiving yards in each of the last three games and should reach the 1,000-yard mark for the fifth straight season.

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Denver Broncos rookie running back R.J. Harvey (ribs) is participating in practice on Wednesday, according to Romi Bean of CBS Colorado. Harvey picked up a rib injury late in Denver's Week 15 win over the Green Bay Packers, but he seems to have avoided a major injury that would cost him any time. Head coach Sean Payton wasn't concerned with the injury, saying that "he's doing good" and should be good to go for Sunday's game against the Jacksonville Jaguars. Payton noted to himself after the Packers game to get Jaleel McLaughlin more touches to manage Harvey's workload, but it's promising news that the rookie won't miss any time. He's been one of the best running backs in fantasy football since taking over lead duties with J.K. Dobbins (foot) out for the year, ranking as the RB6 in PPR points per game over the past four games. Harvey will project favorably again in Week 16 versus the Jaguars.

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