San Francisco 49ers running back Christian McCaffrey (calf) will play in Sunday's season opener against the Seattle Seahawks, according to ESPN's Adam Schefter. McCaffrey had been listed as questionable, and there was genuine concern about his availability after he missed practice on Friday. However, in the end, it appears the star running back will suit up. Fantasy managers should expect him to receive a normal workload, which means he could earn around 20 touches. He remains a very strong mid-range RB1 option thanks to his talent, productivity, and role in an effective Niners offense.

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Dynasty | The Browns have signed rookie running back Quinshon Judkins and he could debut in week two. Dynasty Analysis: This has been a drawn-out ordeal but Judkins got a fully guaranteed deal from Cleveland (they certainly hope this one goes a little better than Deshaun Watson's) and could be ready to play as soon as next week. The NFL is scheduled to interview him this week and a suspension is also a possibility, so anyone with Judkins on their roster simply needs to have a backup plan moving forward until everything is settled. He remains a high-risk rookie with a high ceiling.

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Dynasty | The Lions have signed wide receiver Jameson Williams to an extension. Dynasty Analysis: Williams gets a three-year, $83 million deal with $67 million guaranteed. This ends any drama that was building around a potential exit from Motor City at the end of they year. The Lions are now fully committed to a core of players that includes Amon-Ra St. Brown, Sam LaPorta, Jahmyr Gibbs and Williams. Set to make a big leap this season, the buying window on Williams may be closing.

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Cleveland Browns running back Quinshon Judkins, who finally signed his rookie contract on Saturday, is likely to make his NFL debut in Week 2 against the Baltimore Ravens, a source told ESPN's Adam Schefter. While Judkins' progression through the normal offseason routine was drastically delayed due to his unsigned contract and an off-the-field legal matter, the former was resolved this weekend and the latter could be put to rest within the upcoming week. As a result, Judkins is on track to play next Sunday against the Ravens. With that said, his exact role is still uncertain. He was away from the team during training camp, so it could take him some time to get up to NFL game speed. In the meantime, returning starter Jerome Ford and rookie Dylan Sampson should both carve out significant roles in the Cleveland backfield. Judkins likely won't be startable in fantasy football for at least a few weeks.

From RotoBaller

San Francisco 49ers running back Christian McCaffrey (calf) did not practice on Friday, but he was a "big participant in the walkthrough on Saturday," according to NFL Network's Ian Rapoport. As a result, the star running back is trending toward playing. Fantasy managers are holding their breath and hoping that McCaffrey avoids a repeat of the 2024 season when he was expected to be healthy for Week 1 but then ultimately missed the first nine games. We'll get confirmation on his status around 2:35 p.m. ET when the 49ers post their list of inactive players. If McCaffrey does suit up against the Seahawks, he'll rank as a mid-range RB1 in fantasy football.

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Washington Commanders running back Jacory Croskey-Merritt has been gaining traction throughout training camp and the preseason. The trade of Brian Robinson Jr. has given Croskey-Merritt a clear path to playing time in Washington. The Commanders have stated that Croskey-Merritt will be involved during the season opener. However, it's unclear how much he'll actually play in this game. The Commanders have four backs that they'll probably mix in at some point. Croskey-Merritt is a great stash, but his Week 1 outlook is hard to predict. He's probably best served on the fantasy benches until he has a proven role in the offense.

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Kansas City Chiefs wide receiver Xavier Worthy (shoulder) has suffered a dislocated shoulder from Friday's game in Brazil. Worthy exited in the first quarter of Friday's contest after colliding with teammate Travis Kelce. He underwent additional testing which has now revealed a fairly significant injury. Worthy will still have more testing done, but is hopeful he can return with a brace. It seems tough to imagine Worthy being able to suit up for the Week 2 matchup against the Philadelphia Eagles. If Worthy misses time, Marquise Brown figures to gain the most value. Brown hauled in 10 of 16 targets for 99 yards in the Week 1 loss. Also, JuJu Smith-Schuster, Tyquan Thornton, and Travis Kelce should see increased roles. Brown needs to be rostered in all fantasy formats given Worthy is likely to miss time or be limited.

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Arizona Cardinals quarterback Kyler Murray (illness) has been added to the injury report ahead of Sunday's Week 1 matchup against the New Orleans Saints. At first glance this is concerning, but Murray is still slated to start this game. Possibly, Murray does lose some fantasy value because he'll probably be playing at less than 100 percent. If he misses any snaps, Jacoby Brissett is the primary backup. Despite the illness, Murray should remain in the QB1 discussion with a plus-matchup against the Saints defense.

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Washington Commanders kicker Matt Gay (illness) was recently cleared to suit up for Sunday's Week 1 matchup against the New York Giants. Gay was brought in during the offseason on a one-year, $4.25 million deal. He has bounced around in the league, but had pretty decent success in 2024. Gay knocked down 31-of-37 field goal attempts while hitting 33-of-33 extra point attempts during the 2024 campaign with the Indianapolis Colts. He's not an elite fantasy option, but should get plenty of chances in Washington. Gay is a viable streaming option against the shaky Giants defense in Week 1.

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Carolina Panthers wide receiver Hunter Renfrow has an opportunity to be a factor in Week 1, but many uncertainties surrounding his situation makes him difficult to start right away against the Jacksonville Jaguars. The 29-year-old missed all of 2024 with ulcerative colitis and was initially waived by Carolina, who signed him to the active roster only after dealing Adam Thielen to Minnesota and placing Jalen Coker (quadriceps) on IR. That places Renfrow as Carolina's projected top option in the slot, where he did most of his damage during his stint with the then-Oakland Raiders. The veteran has a 103-catch season to his name, but that was four years ago at this point. For now, Renfrow is mostly a DFS home-run swing or a stash in deeper dynasty formats.

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According to a report from NFL Network's Ian Rapoport, the New York Giants could use rookie quarterback Jaxson Dart as early as Week 1. Rapoport reported that the Giants have a package of plays ready to go for the rookie from Ole Miss, which they are ready to deploy as soon as their season-opening game Sunday against Washington. The Giants signed veteran quarterback Russell Wilson to be their immediate starter, but the drumbeat is already going for Dart, who impressed during the preseason. The Giants traded back into the first round to select the rookie early this year, and the dynamic will be worth watching this season in Superflex and dynasty formats, especially.

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Minnesota Vikings running back Zavier Scott (ankle) has officially been ruled out for his team's road tilt with the Chicago Bears on Monday Night Football. The former undrafted free agent picked up an ankle injury in the Vikes' preseason finale and did not log even a limited practice session ahead of their regular season opener. It's unfortunate timing for Scott, who flashed as a pass-catcher this summer and might have challenged to be Minnesota's third option out of the backfield. Teammates Aaron Jones Sr. and Jordan Mason figure to handle the bulk of the running back opportunities on Monday night, with Ty Chandler potentially rotating in for a few touches behind them.

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The Detroit Lions and wide receiver Jameson Williams have agreed to terms on a three-year, $83 million extension, according to multiple sources. NFL Insider Jordan Schultz reported the news. Per Schultz, the deal includes $67 million in guaranteed money. It's an excellent move by Detroit, who picked up the wideout's fifth-year option back in April. The deal will tie the University of Alabama product to the organization through 2029. Williams is fresh off his best professional season, and the team has indicated he'll be more involved during the 2025 campaign. There was no doubt heading into this year that he'd operate as Detroit's clear-cut No. 2 option, though the extension should quell any lingering fears surrounding him in dynasty.

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Dynasty | Cowboys running back Javonte Williams had 54 rushing yards, two catches, ten receiving yards and two touchdowns in a loss to the Eagles on opening night. Dynasty Analysis: This is bound to be one of the bigger storylines of the week in terms of short-term fantasy league impact. Williams had 17 touches, while Miles Sanders had five and Jaydon Blue was a healthy scratch. The touchdowns mask the fact he only averaged 3.6 yards per carry but this was a big day for Williams as he attempts to resurrect his career. It will be very interesting to see if Blue is activated next week and if he overtakes Sanders, who had a costly fumble in the game. Williams could be a quick trade candidate if you're in a dynasty league and know you're not a contender as his value will be on the rise after this performance.

Dynasty | Cowboys wide receiver George Pickens had three catches for 30 yards in his Dallas debut. Dynasty Analysis: Any idea that Pickens (four targets) would compete with CeeDee Lamb (13) for looks on a weekly basis was likely squashed in this one. Still, you would expect he'd have better days moving forward. He remains a solid flex play but his production could be pretty up and down this season and his first game was a bit of a disappointment.

Dynasty | Chiefs wide receiver Marquise "Hollywood" Brown had ten catches for 99 yards in the Chiefs season opening loss to the Chargers. Dynasty Analysis: Brown had a whopping 16 targets on the night after the Chiefs lost Xavier Worthy to a shoulder injury. Six. Teen. This is a massive development as Worthy could miss more time and Rashee Rice is out for five more games. No other Chiefs receiver had more than five targets on the night and this performance is going to vault Brown right into weekly lineup consideration. He's also going to be a prime player to move via trade to a contending team if you're not going to be in contention because he's going to offer short-term upside but also likely fail to keep up this kind of momentum when the Chiefs get back to full strength.

Dynasty | Chiefs tight end Travis Kelce had two catches for 47 yards and a touchdown in the Chiefs opening night loss to the Chargers. Dynasty Analysis: The fantasy stats for the week will have the soon-to-be Swift husband towards the top of the rankings but this performance was very concerning. On a night where the Chiefs were without both Rashee Rice (suspension) and Xavier Worthy (Kelce accidentally ran into him and knocked him out the game), Kelce still only had four targets. Despite saying all the right things about being young and rejuvenated, Kelce looks like a player well past his prime. Dynasty managers need to seriously consider what to do as the bottom may very well fall out in the coming weeks.

Tampa Bay Buccaneers kicker Chase McLaughlin will look to keep the good times rolling after a strong 2024 campaign. McLaughlin posted a career-high 93.8 percent conversion rate on field-goal attempts last season. The 29-year-old knocked down 30-of-32 field goals and 54-of-56 extra point attempts across 17 games with the Bucs. He'll enter his third season in Tampa Bay as it appears McLaughlin has found a long term home. The Bucs have a strong enough offense to give McLaughlin plenty of opportunities. McLaughlin should be considered a strong kicking option in what could be a high-scoring game in Week 1 versus the Atlanta Falcons.

From RotoBaller

Minnesota Vikings RB Jordan Mason and RB Aaron Jones should see plenty of carries, especially early in the season, because a running game is 'what makes the quarterback's job easier,' according to head coach Kevin O'Connell.

Fantasy Spin: The Vikings will be breaking in quarterback J.J. McCarthy, and O'Connell has made it clear he plans to lean on his running backs while McCarthy finds a comfort level. As last year's starter and the more versatile back, Jones has the safer floor among the duo. However, Mason has been an efficient runner throughout his career and has potential as a flex option.

From TheHuddle

According to Dianna Russini of The Athletic, Los Angeles Rams head coach Sean McVay views quarterback Jimmy Garoppolo as a "starting-caliber" option. Matthew Stafford is in line to start on Sunday versus the Houston Texans. However, with the veteran signal-caller battling a lingering back injury, the Rams are confident Garoppolo can fill in admirably if necessary. From a fantasy standpoint, Stafford has had a better career. Still, with concerns about his health, Garoppolo may get a chance to start at some point moving ahead. The 33-year-old played for the Patriots, 49ers, and Raiders before arriving in Los Angeles in 2024 to suit up for the Rams. In 82 regular-season contests, he's thrown for 15,828 yards, 96 touchdowns, and 52 interceptions off 67.4% passing while also leading the 49ers to the Super Bowl in 2019. All things considered, Garoppolo doesn't have much fantasy value at the moment. If Stafford goes down this season due to the nagging back issue, Garoppolo could prove useful for those participating in deeper SuperFlex formats, especially with Puka Nacua and Davante Adams at his disposal.

From RotoBaller