Buffalo Bills wide receiver Keon Coleman will be a healthy scratch for a second straight game on Thursday night against the Houston Texans, a source told ESPN's Alaina Getzenberg. The Bills held Coleman out of last Sunday's win over the Tampa Bay Buccaneers after he was late to a team meeting last Friday. Tight end Dalton Kincaid (hamstring) and receiver Curtis Samuel (elbow, neck) have been ruled out, and Mecole Hardman (calf) was put on Injured Reserve, so Buffalo's offense isn't exactly teeming with weapons for quarterback Josh Allen. Coleman, 22, will be missing his fourth game in two years due to disciplinary reasons, and he's quickly turned into a bust for the Bills and fantasy managers. He has 32 catches this year for 330 yards and three touchdowns. With Coleman out again, Gabe Davis and Tyrell Shavers will have bigger roles alongside Khalil Shakir and Joshua Palmer.

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Green Bay Packers running backs coach Ben Sirmans said he thinks running back MarShawn Lloyd (hamstring) will play this year, according to Rob Demovsky of ESPN. "He's pretty excited about some of the things he's doing," Sirmans said. The RB coach said Lloyd told him, "I'm coming back and this is going to be it. It's the last time." The 24-year-old has yet to play in 2025 due to a hamstring injury, but Lloyd only played in one game in his rookie season due to injuries, too. He has been working his way into better shape away from the team, but it remains to be seen when he'll be activated from Injured Reserve. Lloyd could be getting closer to rejoining the team in practices, but he will not be available this Sunday when they play the division-rival Minnesota Vikings, potentially without star RB Josh Jacobs (knee). Lloyd is only rostered in 1% of Yahoo leagues right now.

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Cleveland Browns tight end David Njoku (knee) missed another practice on Thursday, according to Scott Petrak of Browns Zone. The Browns listed Njoku as day-to-day to begin the week with a knee injury that he picked up in the Week 11 loss to the Baltimore Ravens. After two straight DNPs, though, the 29-year-old is on the wrong side of questionable to play this Sunday against the Las Vegas Raiders. If Njoku is unable to play in Week 12, it will open up more targets for rookie tight end Harold Fannin Jr. in what will be rookie quarterback Shedeur Sanders' first career start. The Raiders might seem like a good matchup on paper for Fannin, but they've allowed the fourth-fewest half-PPR points to the tight end position in 2025. In theory, Fannin should see more looks, but he'll also be a bigger risk in Sanders' first NFL start.

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Dallas Cowboys quarterback Dak Prescott (hip) was a full participant on Thursday after he was limited in Wednesday's session due to a hip injury, according to Clarence Hill Jr. The Cowboys downplayed Prescott's hip injury on Wednesday, even though he was limited in the walkthrough practice. The 32-year-old veteran signal-caller should be a full-go for a divisional battle this weekend against the Philadelphia Eagles on Sunday. In the first meeting against Philly in Week 1 in a 24-20 loss, Prescott went 21-for-34 passing for a season-low 188 yards, no touchdowns, and no interceptions. There's no question that the Eagles have one of the better defenses in the league, so it would be a surprise if Prescott throws for four touchdowns like he did against the Raiders on Monday night. Still, he should be considered a low-end QB1 option with one of the best 1-2 punches at receiver in CeeDee Lamb and George Pickens.

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Baltimore Ravens QB Lamar Jackson (ankle) fully participated in practice Thursday, Nov. 20.

Fantasy Spin: The Ravens are being cautious with Jackson, but he should not have any limitations this week against the New York Jets. He has thrown for at least 250 yards in only one of his games this season but still has 15 passing touchdowns in seven games. He will be a No. 1 quarterback in all fantasy leagues this week.

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Baltimore Ravens WR Rashod Bateman (ankle) and CB Keyon Martin (rib) did not participate in practice Thursday, Nov. 20. S Kyle Hamilton (groin, shoulder), TE Isaiah Likely (calf), LB Roquan Smith (hamstring) and OG Andrew Vorhees (foot) were limited during practice. RB Justice Hill (toe), CB Marlon Humphrey (finger), QB Lamar Jackson (ankle) and OT Ronnie Stanley (illness) fully participated in practice.

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Dallas Cowboys QB Dak Prescott (hip) fully participated in practice Thursday, Nov. 20.

Fantasy Spin: Prescott currently ranks fifth in the NFL with 2,587 passing yards and also is tied for second with 21 passing touchdowns. He will be facing a good defense this week but can still be a low-end No. 1 quarterback in fantasy leagues.

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Arizona Cardinals running back Trey Benson (knee) was limited for the second day this week on Thursday as he attempts to return from a knee injury that has kept him out since Week 4, according to Zach Gershman of AZCardinals.com. Benson's 21-day practice window was opened on Wednesday, which means he's eligible to come off Injured Reserve and play this Sunday against the visiting Jacksonville Jaguars. The 23-year-old had surgery for a meniscus injury that he suffered in Week 4. Benson will most likely need a full practice on Friday for Arizona to even consider activating him from IR. The team's backfield is beat up going into the weekend, with Emari Demercado (ankle) already ruled out and Bam Knight (ankle) being limited so far in practice. All signs are pointing to Benson missing this week, with Knight and Michael Carter sharing backfield duties versus the Jags.

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Kansas City Chiefs running back Isiah Pacheco (knee) was listed as a limited participant in practice on Thursday due to a knee injury that has kept him out of the team's last two games. Pacheco was listed as a full-go on Wednesday, so it remains to be seen if he'll be cleared to play this Sunday against the Indianapolis Colts. The 26-year-old has been wearing a bulky brace on his right knee in his return to practice this week. It's unclear if he suffered a setback on Thursday or if he is being rested by KC, but we should have a clearer picture of his Week 12 status on Friday. Fantasy managers shouldn't be feeling great about Pacheco's value coming off a two-game absence if he ends up being cleared to face the Colts. Pacheco's upside has been limited this year with veteran Kareem Hunt serving as the team's preferred goal-line option. If he plays against Indy, Pacheco will be a touchdown-dependent RB3/flex, at best.

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New York Giants wide receiver Darius Slayton (hamstring) was upgraded to a limited practice on Thursday as he battles through a hamstring injury, according to Jordan Raanan of ESPN. After missing practice on Wednesday, Slayton now has a chance to play on Sunday against the Detroit Lions. This is the first time that Slayton will be back at practice since he injured his hamstring in Week 10. The 28-year-old did not play in last Sunday's loss to the Green Bay Packers. He might need to upgrade to a full practice on Friday to avoid a questionable tag heading into Sunday's game on the road against the Lions. If Slayton can return this weekend, he'll be in play as a flex option for fantasy managers for a Giants team that could be getting rookie quarterback Jaxson Dart back from a concussion. Slayton has yet to score in 2025, but he should see a healthy dose of targets if he plays in a Week 12 matchup that should force the Giants to the air often. He has a 23-343-0 line in eight games this season.

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San Francisco 49ers quarterback Brock Purdy (toe) is a full-go at the first practice of the week on Thursday, according to head coach Kyle Shanahan. Purdy returned in Week 11 for the first time since aggravating a turf-toe injury in Week 4 and looked good, going 19-for-26 passing for 200 yards and three touchdowns in a blowout win over the Arizona Cardinals. The 25-year-old managed to avoid a setback with his toe and should be a full-go for the Monday night clash against the Carolina Panthers in Week 12. The Panthers' defense has been much-improved from a season ago and hasn't been a great matchup for opposing QBs in 2025, but Purdy should still be viewed as a midrange QB1 in fantasy football now that the Niners' offense is pretty much back to full strength for the first time all year. The one drawback to starting Purdy in fantasy lineups is that he might still be hesitant to run the ball because of his toe injury. He ran just once last week for a loss of seven yards.

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The Buffalo Bills elevated wide receiver Gabe Davis to the 53-man active roster for Thursday night's game against the Houston Texans after placing receiver Mecole Hardman (calf) on Injured Reserve, according to Ian Rapoport of NFL Network. Hardman was injured in his season debut with Buffalo in Sunday's win over the Tampa Bay Buccaneers and will now be forced to miss at least four games. The 27-year-old won't be eligible to return until Dec. 14 against the division-rival New England Patriots. Davis also made his season debut last weekend with Buffalo, catching three of his four targets for 40 yards in the 44-32 win. Veteran Curtis Samuel (elbow, neck) is also out for Thursday night, and second-year wideout Keon Coleman could be a healthy scratch for a second straight week. Meanwhile, Khalil Shakir missed practice time with a personal issue this week, and tight end Dalton Kincaid (hamstring) is out. Davis could have a bigger role in Week 12, albeit against the best defense in the NFL.

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Atlanta Falcons WR Drake London (knee), LB Josh Woods (hamstring) and DE Zach Harrison (knee) did not participate in practice Thursday, Nov. 20. LB Leonard Floyd (hamstring), OG Chris Lindstrom (foot) and OG Matthew Bergeron (ankle) were limited during practice. LB Divine Deablo (forearm), CB Dee Alford (concussion), CB Mike Hughes (neck), S Xavier Watts (illness), LB Malik Verdon (shoulder) and DE Brandon Dorlus (oblique) fully participated in practice.

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Cincinnati Bengals quarterback Joe Flacco (shoulder) was listed as a limited practice participant for the second straight day on Thursday as he battles a right shoulder issue, per Kelsey Conway of the Cincinnati Enquirer. It's worth noting that Flacco has been playing through the shoulder injury for multiple weeks, so his status for Week 12 against the New England Patriots may not ultimately be in question. However, star Bengals quarterback Joe Burrow (toe) logged his second straight full practice on Thursday as he nears a return from the toe injury that has had him on Injured Reserve since Week 2. If Burrow is cleared to play in Week 12, that would obviously send Flacco to the bench regardless of the status of his shoulder. Flacco has largely been effective in his starts for the Bengals this season, but he struggled in Week 11 against the Pittsburgh Steelers. If Burrow remains sidelined and Flacco is pressed into action for another game, he profiles as a solid fantasy QB2 in Week 12.

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The Houston Texans have waived running back Dameon Pierce, per Jonathan M. Alexander of the Houston Chronicle. A fourth-round pick of the Texans in 2022, Pierce burst onto the scene as a rookie by rushing for 939 yards and four touchdowns on 220 carries across 13 games. However, injuries and ineffectiveness have plagued him basically ever since. Across four games this season, Pierce had logged just 26 rushing yards on 10 carries. The 25-year-old was buried behind Woody Marks, Nick Chubb, and Dare Ogunbowale on the running back depth chart in Houston and had not recorded an offensive snap since Week 5. Pierce will now search for a new home for the remainder of the 2025 season. Regardless of where he ends up, Pierce is unlikely to play a fantasy-relevant role.

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Indianapolis Colts quarterback Daniel Jones (calf) was added to the team's Thursday injury report and listed as a limited practice participant due to a calf issue. While the severity of the injury is unclear, it's never a great sign for a player to be added to the injury report in the middle of the week, and it could be an indication that Jones suffered the ailment during practice. Across 10 games this season, the 28-year-old has completed 69.9% of his pass attempts for 2,659 yards, 15 touchdowns, and seven interceptions. Jones has also been a threat with his legs, rushing for 143 yards and five scores on 40 attempts. If he's unable to play in Week 12, rookie quarterback Riley Leonard would be in line to make the start on Sunday against the Kansas City Chiefs. Should Jones be active, he profiles as a borderline fantasy QB1 against Kansas City, although a calf injury could impact his effectiveness as a runner.

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Minnesota Vikings OT Christian Darrisaw (knee) did not participate in practice Thursday, Nov. 20. OG Will Fries (knee) and DE Jonathan Greenard (shoulder) were limited during practice. RB Aaron Jones (shoulder) and C Ryan Kelly (concussion) fully participated in practice.

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Cincinnati Bengals quarterback Joe Burrow (toe) practiced in full for the second straight day on Thursday, per ESPN's Adam Schefter. The star quarterback has been on Injured Reserve since mid-September after suffering a toe injury in Week 2. However, it appears as though Burrow is nearing a return to the field in either Week 12 against the New England Patriots or Week 13 against the Baltimore Ravens. Across 17 games in 2024, Burrow completed 70.6% of his pass attempts for 4,918 yards, 43 touchdowns, and nine interceptions. Assuming he can operate at full or near-full strength when he returns to the field, Burrow profiles as a must-start fantasy quarterback and holds league-winning upside down the stretch of the fantasy season. In the short term, Burrow's availability for Week 12 is unlikely to be determined until Friday. If he remains sidelined, veteran quarterback Joe Flacco (shoulder) would be in line to make his sixth straight start for Cincinnati.

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Indianapolis Colts DT Grover Stewart (non-injury) did not participate in practice Thursday, Nov. 20. DE Samson Ebukam (knee), QB Daniel Jones (calf) and DE Tyquan Lewis (groin) were limited during practice. LB Jaylon Carlies (ankle), WR Anthony Gould (knee), CB Kenny Moore II (non-injury) and CB Charvarius Ward (concussion) fully participated in practice.

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Minnesota Vikings RB Aaron Jones (shoulder) fully participated in practice Thursday, Nov. 20.

Fantasy Spin: Jones should be able to handle his normal workload this week in the running game and will probably also see a few targets in the passing game. He can be considered a No. 2 running back or flex option in fantasy leagues.

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