Los Angeles Chargers running back Kimani Vidal is expected to see significant usage in Week 13 after rushing for only 13 yards on five carries against the Jacksonville Jaguars in Week 11. Teammate Hassan Haskins (hamstring) remains on IR, and rookie Omarion Hampton (ankle) has been ruled out, even though the team opened his 21-day practice window earlier this week. Vidal has been inconsistent lately, but is likely to handle most of the carries against the Las Vegas Raiders. The Raiders have a surprisingly strong run defense, allowing just 3.7 yards per carry (second-best in the league), which could challenge Vidal's efficiency. However, the Raiders' defense is also the league's worst at stopping goal-line touchdowns, boosting Vidal's scoring upside in a game where the Chargers' coaching staff might lean on the run if the team gets an early lead. Given the opportunity and Hampton's injury status, Vidal should be upgraded to a mid-range RB2 for this week.

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Arizona Cardinals wide receiver Marvin Harrison Jr. (illness) is listed as questionable for Sunday against the Tampa Bay Buccaneers, according to Bo Brack of PHNX Cardinals. Harrison was a limited participant every day this week in practice after missing the previous two games after undergoing an appendectomy surgery. The second-year wideout said that he feels good two weeks removed from surgery, but it's still to be determined if he will be able to return in Week 13. Harrison has collected 34 receptions for 525 yards and four touchdowns on 62 targets in nine games this season. Michael Wilson and Greg Dortch have emerged for the Cardinals in his absence and would be in for big roles again in Week 13 against the Bucs if Harrison is unable to suit up again.

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Los Angeles Chargers quarterback Justin Herbert enters Week 13 eager for a bounce-back after his worst performance of the season in Week 11. In the team's disappointing 35-6 loss to the Jacksonville Jaguars, Herbert completed just 10 of 18 passes for 81 yards and threw an interception before being benched early, marking his first game without a passing touchdown this season. For the upcoming game against the Las Vegas Raiders, Herbert should find better success despite the Raiders not having allowed a 300-yard passer this season. The Las Vegas defense plays zone coverage at the second-highest rate, where Herbert ranks middle-of-the-pack. However, his battered offensive line has allowed 35 sacks this season. That vulnerability raises concerns that Head Coach Jim Harbaugh and Offensive Coordinator Greg Roman hopefully addressed during the bye week. If the Chargers' defense can contain the struggling Las Vegas offense, the game may lean more toward a balanced running attack. RotoBaller ranks Herbert as QB9 this week, making him a solid but somewhat risky low-end QB1 with a limited ceiling due to protection and scheme issues.

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Tampa Bay Buccaneers running back Bucky Irving (shoulder, foot) fully practiced for the third straight day on Friday, but is listed as questionable for Week 13 against the Arizona Cardinals, Rick Stroud of the Tampa Bay Times reports. However, head coach Todd Bowles said Friday that Irving is trending towards returning on Sunday for the first time since Week 4. The 23-year-old suffered a foot sprain and a subluxation of his shoulder during Tampa Bay's Week 4 loss to the Philadelphia Eagles, and after missing a significant amount of time, his snaps and touches are expected to be limited on Sunday. The second-year back will split touches with both Sean Tucker and Rachaad White, creating a somewhat murky situation for fantasy managers. Irving is ranked as RotoBaller's RB24 in PPR leagues for Week 13.

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Los Angeles Chargers rookie running back Omarion Hampton (ankle) has officially been ruled out for Sunday's game against the Las Vegas Raiders, according to Alex Insdorf of the Bolt Beat. Hampton has been sidelined since Week 5, and it was recently reported that he was dealing with a fractured ankle. The rookie first-rounder was listed as limited every day in practice this week, and will need at least another week before he's ready to go. It's also possible that Hampton operates in a timeshare with second-year back Kimani Vidal when he returns, as indicated by offensive coordinator Greg Roman. That could limit the rookie's rest of season upside, but he was producing at a high level before going down with injury, recording 66 carries for 314 yards and two touchdowns along with 20 receptions (22 targets) for 136 yards as a receiver. Vidal is in line to handle the bulk of the touches again in Week 13 against the Raiders.

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Tampa Bay Buccaneers quarterback Baker Mayfield (left shoulder) was a full participant in Friday's practice session, but is listed as questionable for Sunday's matchup against the Arizona Cardinals, according to Ian Rapoport of NFL Network. Mayfield was upgraded to full after missing Wednesday's practice and being limited on Thursday. Head coach Todd Bowles said that the 30-year-old looked good in practice on Friday and is trending towards playing on Sunday against the Cardinals. Mayfield suffered a low-grade AC joint sprain to his left shoulder during Tampa Bay's Week 12 loss to the Los Angeles Rams, and while he has a favorable matchup this week against an Arizona defense that has struggled recently, he projects as more of a high-end QB2 in Week 13 with the possibility of a re-injury.

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The circumstances for Minnesota Vikings wide receiver Justin Jefferson have gone from bad to worse as the Vikings will be down to their third-string quarterback in Week 13 at the Seattle Seahawks. Already without backup Carson Wentz (shoulder) for the season, starter J.J. McCarthy (concussion) will miss yet another game, leaving undrafted rookie Max Brosmer to make his first NFL start. The Vikings also could be without star left tackle Christian Darrisaw (knee, foot) and have ruled out starting left guard Donovan Jackson (ankle). Against a Seattle defense allowing scoring drives at the second-best rate in the league, it's tough sledding even for one of the league's best receivers. Jefferson has performed with poor QB play before, but given the long odds, he should be considered more of a WR2 or high-end flex this week.

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Arizona Cardinals running back Emari Demercado (ankle) has been ruled out for his team's Week 13 matchup against the Tampa Bay Buccaneers, per Darren Urban of azcardinals.com. Week 13 will mark Demercado's second straight missed game due to an ankle injury. With Demercado and Trey Benson (knee) remaining out in Week 13, the Cardinals' backfield remains wide open. Bam Knight (knee) has been the team's lead back in recent weeks, but he's listed as questionable to play himself due to a knee injury. If Knight is out or limited, Michael Carter could take over the lead role in the Arizona backfield. Jermar Jefferson could also see some work in Arizona after being active for the first time in 2025 in Week 12.

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Minnesota Vikings running back Jordan Mason is far down the list of fantasy options with his offense in rough shape as it prepares to take on the Seattle Seahawks in Week 13. The Vikings will be down to their third-string quarterback, undrafted rookie Max Brosmer, who has never made a start in the NFL before. Minnesota will be without left guard Donovan Jackson (ankle), and could also be missing star left tackle Christian Darrisaw (knee, foot). Additionally, Seattle ranks fourth against half-PPR running backs. Mason has two catches in four November games and is averaging 6.4 rushing attempts in Minnesota's past five games, diminishing his fantasy value as Minnesota has preferred Aaron Jones Sr. when both backs have been available. Ranked as RotoBaller's No. 47 running back for Week 13, Mason is a big risk in fantasy lineups this week.

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Minnesota Vikings running back Aaron Jones Sr. has been solid when available, but a bad draw in Week 13 against Seattle makes him a risky start in fantasy lineups. Jones has finished between No. 12 and No. 27 among PPR running backs in four straight games, even in the midst of the team's offensive struggles, but this week may bring a new level of unpredictability. Due to injuries, Minnesota will play undrafted rookie quarterback Max Brosmer, who has never started an NFL game. They will also be without left guard Donovan Jackson (ankle), while standout left tackle Christian Darrisaw (knee, foot) is questionable. All of this comes against a Seattle defense that ranks seventh against PPR running backs. Jones gets enough receiving work to be in RB3/flex consideration, but managers can't be faulted for avoiding the Vikings' offense this week.

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The Minnesota Vikings will turn to undrafted rookie Max Brosmer in Week 13 at Seattle, but fantasy managers should consider him the single biggest risk of the weekend. Already without backup Carson Wentz (shoulder) following season-ending surgery, the Vikings will once again be without starter J.J. McCarthy (concussion), who was unable to clear protocol in time to play. The Vikings have a talented group of skill players led by receiver Justin Jefferson, but the Seahawks' defense has allowed scoring drives on fewer than 31% of opposing possessions, which is the second-best mark in the NFL. Ranked as RotoBaller's No. 32 fantasy quarterback this week, Brosmer is a huge unknown facing unfriendly circumstances, making him a tough start in any format.

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The Minnesota Vikings' season has gone from bad to worse, and tight end T.J. Hockenson now finds himself in TE3 territory as the club travels to Seattle in Week 13. The Vikings will not only be without starter J.J. McCarthy (concussion), but backup Carson Wentz (shoulder) is already out for the season, leaving the team to start undrafted rookie Max Brosmer against a strong Seattle defense that is allowing scoring drives at the second-lowest rate in the NFL. Hockenson has cracked the top 15 PPR tight ends only once this season, and now he's relying upon a complete unknown under center. Predictably, the Vikings are the biggest underdog of the weekend, so managers rostering Hockenson may want to steer clear of this entire situation, even in formats that start two tight ends.

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New Orleans Saints running back Devin Neal (ankle) will not carry an injury designation into Week 13 and is "good to go" for his team's matchup on Sunday against the Miami Dolphins, per Mike Triplett of New Orleans.Football. Neal was a limited practice participant on both Wednesday and Thursday due to the ankle issue, but was able to log a full session on Friday. With veteran Saints back Alvin Kamara (knee, ankle) officially ruled out for Week 13, Neal could have the chance to lead his team's backfield against Miami. Across seven games played this season, the rookie sixth-rounder has recorded 125 scrimmage yards on 29 touches. Neal did most of his work as a receiver in Week 12 after Kamara was forced to exit the game, hauling in five catches for 43 yards on seven targets. He profiles as a low-end fantasy RB2 in Week 13 against Miami.

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As the Minnesota Vikings prepare to start an undrafted rookie quarterback, Jalen Nailor is a low-end wide receiver option in Week 13 at Seattle. The Vikings are down to their third-string quarterback, Max Brosmer, who has never made a start in the NFL. The circumstances have considerably dimmed the prospects for everyone on the Minnesota offense, but especially Nailor, who already was facing an inconsistent target share behind fellow receivers Justin Jefferson and Jordan Addison. After a breakout Week 10 game, Nailor had just two combined targets in the next two games, which is nowhere near enough to rely upon in any fantasy format. Now, with even tougher circumstances ahead, Nailor can safely remain on waiver wires in the majority of fantasy formats.

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As the Minnesota Vikings' season circles the drain, wide receiver Jordan Addison's weekly ranking has dipped outside the top 50 for Week 13 against the Seattle Seahawks. Ranked as RotoBaller's No. 53 half-PPR receiver for this week, Addison is facing hugely unknown circumstances with the Vikings down to third-string quarterback Max Brosmer. Starter J.J. McCarthy (concussion) will miss the game, while backup Carson Wentz (shoulder) already was out for the year following season-ending surgery. Fantasy managers who have started Addison recently have seen diminishing returns, as he has a total of seven catches in November during the Vikings' offensive struggles. Against a strong Seattle defense, Addison should be considered a risky option in most formats in Week 13.

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Atlanta Falcons wide receiver Drake London (knee) has officially been ruled out for his team's Week 13 matchup against the New York Jets, per ESPN's Marc Raimondi. London suffered a PCL injury in Week 11 that will now sideline him for at least two games. His absence creates a major void in Atlanta's passing game, as London has recorded 60 receptions for 810 yards and six touchdowns on 94 targets across the nine games he's been healthy for in 2025. With London sidelined in Week 12 against the New Orleans Saints, tight end Kyle Pitts led the team in targets with five. Wide receiver Darnell Mooney led the team with 74 receiving yards, and he was one of four Falcons to see exactly three targets from quarterback Kirk Cousins. Mooney profiles as a low-end fantasy WR3 in Week 13 against New York.

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Cincinnati Bengals kicker Evan McPherson had a productive night in Thursday's win over the Baltimore Ravens, draining a career-high six of his six attempts. The 26-year-old had a quiet start to begin the 2025 campaign. However, with the Bengals offense clicking, he's been more involved since going 4-for-4 in the meeting with the Pittsburgh Steelers on October 16. With Joe Burrow (toe) back in the equation, the Bengals offense could have an easier time getting up and down the field, especially if the defense plays as well as it did on Thanksgiving. If that happens, McPherson should have no problem remaining one of the best fantasy kickers going. Keep him starting in Week 14 versus the Bills, assuming the weather in Buffalo cooperates.

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New Orleans Saints wide receiver Chris Olave (back) is officially questionable to play in his team's Week 13 matchup against the Miami Dolphins due to a back injury. Olave was a limited practice participant on Friday due to the injury after being held out of practice completely on Thursday. Across 11 games this season, the 25-year-old has hauled in 69 catches for 734 yards and four touchdowns on 108 targets. If unable to go in Week 13, Saints tight end Juwan Johnson might be the team's leading target earner against Miami, while wide receivers Devaughn Vele and Mason Tipton would likely both see an uptick in playing time. Should Olave be able to play, he's a good bet for double-digit targets and profiles as a must-start fantasy wide receiver in PPR formats.

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Minnesota Vikings quarterback J.J. McCarthy (concussion) remains in the NFL's concussion protocol and has officially been ruled out for his team's Week 13 matchup against the Seattle Seahawks, per ESPN's Adam Schefter. With McCarthy sidelined, undrafted rookie Max Brosmer will make his first NFL start against Seattle. McCarthy's latest injury is the latest setback in what's been a disastrous 2025 season for the 22-year-old. He's completed just 54.1% of his pass attempts and thrown 10 interceptions across six starts this season, and Week 13 will mark his sixth missed game due to injury. If Brosmer produces in a tough spot against the Seahawks, there's a chance he could get an extended look as the Minnesota starter. In his senior season at the University of Minnesota in 2024, Brosmer completed 66.5% of his pass attempts for 2,828 yards, 18 touchdowns, and six interceptions across 13 games played.

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Cincinnati Bengals wide receiver Mitchell Tinsley had two catches for 22 yards in Thursday's win over the Baltimore Ravens. With Tee Higgins (concussion) sidelined for this one, there were extra targets up for grabs from the returning Joe Burrow (toe). Naturally, Ja'Marr Chase led the way by receiving 14 targets. However, Tinsley finished behind him with nine. The wideout also had a few chances to find the end zone. All things considered, it appears Tinsley could be in line for continued attention from Burrow in Week 14 against the Buffalo Bills if Higgins remains on the shelf. Still, even with the potential for added involvement, Tinsley is hard to trust in any fantasy format.

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