New Orleans Saints running back Alvin Kamara (knee) suffered an MCL sprain during his team's Week 12 loss to the Atlanta Falcons and may now be facing missed time. With fellow Saints back Kendre Miller (knee) out for the season, there is a clear opportunity for playing time in the New Orleans backfield. Rookie sixth-rounder Devin Neal looks like the most likely candidate to step in as the Saints' lead back if Kamara misses time. However, Audric Estime is another running back who could see a significantly increased role. A fifth-round pick in the 2024 draft by the Denver Broncos, Estime recorded 310 rushing yards and two touchdowns on 76 carries across 13 games with Denver as a rookie. He was released by the Broncos before the start of the 2025 season and has spent most of the year on the Saints' practice squad. Now on New Orleans' active roster, Estime could get his chance to re-establish his NFL career. He could be a player to target on the waiver wire in deep fantasy leagues ahead of the Saints' Week 13 matchup against the Miami Dolphins.

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Baltimore Ravens head coach John Harbaugh said that wide receiver Rashod Bateman (ankle) was a full participant in practice on Tuesday. However, the team's official injury report lists Bateman as a limited participant for the second straight day. The 25-year-old has missed his team's last two games due to an ankle injury and does not appear certain to make his return for Baltimore's Week 13 matchup against the Cincinnati Bengals on Thanksgiving night. Across nine games this season, Bateman has recorded 16 catches for 194 yards and two touchdowns on 31 targets. If he remains sidelined on Thursday, veteran Ravens wideout DeAndre Hopkins would be the most likely beneficiary from a playing time perspective. Regardless of whether Bateman is active or not, Baltimore WR1 Zay Flowers remains the only Ravens wide receiver who should be on fantasy radars in Week 13.

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Philadelphia Eagles running back Saquon Barkley (groin) was limited in Tuesday's practice due to a groin injury, according to Ian Rapoport of NFL Network. Barkley originally tweaked his groin in Week 8 against the New York Giants, but he hasn't missed any time because of it. The Eagles are likely just managing the injury and being cautious on a short week with the team facing the Chicago Bears on Black Friday in Week 13. Barkley still has two more days to return to a full practice, so he could be removed from the final injury report by Thursday. The 28-year-old has disappointed in 2025 in comparison to his monster 2024 campaign. Barkley had only 10 carries for 22 yards in the Week 12 loss to the Dallas Cowboys after seeing 20-plus carries in each of the previous two games. He salvaged his fantasy line, though, with a season-high seven catches for 52 yards on eight targets. If Barkley were to miss Friday's game, Tank Bigsby would likely see most of Philly's backfield touches.

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The Green Bay Packers are not ruling out wide receiver Jayden Reed (foot, shoulder) from coming off Injured Reserve to play on Thursday in the Thanksgiving Day game against the division-rival Detroit Lions at Ford Field, according to ESPN's Rob Demovsky. "You never know... You'll find out Thursday," head coach Matt LaFleur said when asked if Reed could play on Thursday, given the lack of practice time. Reed practiced for the first time last Friday since breaking his collarbone in Week 2. He was limited on Friday and on Monday and Tuesday of this week, putting his status up in the air for Week 13. In addition to a broken collarbone, the third-year pass-catcher is recovering from surgery to fix a fractured foot. At the very least, fantasy managers should stash Reed, who has scored 18 total touchdowns in 35 career games. Green Bay will likely wait to activate him for a Week 14 contest against the Bears. If he is active on Thursday, his reps will most likely be limited, making him a fade candidate in fantasy.

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Philadelphia Eagles wide receiver DeVonta Smith (chest, shoulder) was listed as a non-participant in Tuesday's walkthrough practice due to chest and shoulder injuries, according to Tom Pelissero of NFL Network. Smith's status bears watching on a short week when the team takes on the Chicago Bears on Friday. He played 95% of the offensive snaps in the Week 12 loss to the Dallas Cowboys on Sunday and had a big game, catching six of his 11 targets for 89 yards. If Smith is a DNP again on Wednesday, fantasy managers should actually be worried that he might be in danger of missing Week 13 action. If Smith is limited in any way or ruled out entirely against Chicago later this week, Jahan Dotson would be in line for WR2 duties in Philly behind A.J. Brown. Smith has only found the end zone three times in 11 games in 2025, adding 55 receptions on 78 targets for 754 yards. He's on track for the third 1,000-yard season in his fifth NFL campaign.

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Kansas City Chiefs running back Dameon Pierce was signed to the practice squad on Monday. This news comes after Pierce was cut by the Houston Texans last week. The 25-year-old barely had a role in Houston, so a change of scenery was needed. This wasn't a perfect landing spot, but Pierce should see more action in Kansas City. Lead back Isiah Pacheco (knee) is currently banged up, but is expected to play against the Dallas Cowboys on Thanksgiving. Outside of that, Kareem Hunt is the primary backup with Brashard Smith getting mixed in as well. At the moment, Pierce doesn't seem to have a path to consistent playing time, but that could change if Pacheco is unable to play. Fantasy managers should keep Pierce on their radar if someone goes out.

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Los Angeles Rams tight end Colby Parkinson has been putting together a nice stretch of play over the last few weeks. Over the last three games, Parkinson has hauled in 10 receptions for 96 yards and three touchdowns. He has taken on a larger role in the offense with Tyler Higbee (ankle) landing on the injured reserve. Parkinson has shown he is capable of the TE1 role and is looking like a viable red zone threat. Fantasy managers in need of a possible streaming option in Week 13 should look at Parkinson for his matchup against the Carolina Panthers.

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Miami Dolphins tight end Darren Waller (pectoral) will have his 21-day practice window opened this week, according to head coach Mike McDaniel. Waller has been sidelined since suffering a pectoral injury in Week 7. Before going down, Waller hauled in 10 receptions for 117 yards and four touchdowns in four games. The 33-year-old was surprisingly a popular target especially in the red zone before getting injured. Once healthy, Waller figures to resume his duties at the top tight end in this offense. It's unclear at the moment if he'll be ready in time to play against the New Orleans Saints in Week 13. Regardless, Waller could be worth a stash for fantasy managers in need of tight end help going forward. The veteran tight end figures to be back in the mix soon.

From RotoBaller

Houston Texans quarterback C.J. Stroud (concussion) is hopeful to get back on the field for the Week 13 matchup against the Indianapolis Colts. Stroud has been sidelined since he suffered a concussion during the Week 9 matchup against the Denver Broncos. He remained in concussion protocol to begin the week, but the organization is optimistic he'll be ready to go this weekend. If he plays, Stroud should immediately return to having viable streaming value. During his last full game, Stroud threw for over 300 yards with two touchdowns. The 24-year-old should creep into the QB1 conversation, assuming he's cleared to play this weekend.

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Miami Dolphins quarterback Tua Tagovailoa is hopeful for better results after a few lackluster performances before the bye in Week 12. Tagovailoa has been held to 205 passing yards or fewer in three of his last four games. Despite that, Tagovailoa did have a four-touchdown game during that span. The 27-year-old is an intriguing option heading into the Week 13 matchup against the New Orleans Saints. The Dolphins should come into this game refreshed after the bye and will face off against an average pass defense. Fantasy managers in need of a possible streaming option might want to consider Tagovailoa who should offer at least QB2 value.

From RotoBaller

Miami Dolphins running back Ollie Gordon II could see a larger role in this rushing attack coming out of the bye week. In Week 11, Gordon rushed the ball nine times for 45 yards and scored a touchdown in the win over the Washington Commanders. The rookie back saw a season-high 39 percent of the offensive snaps during that contest. His nine touches on the ground also tied for the second-most Gordon has seen this season. The rookie back has proven to be a viable option when given the chances in this offense. He could see an expanded role in the offense when the Dolphins take on the New Orleans Saints in Week 13. The 21-year-old could be worth a stash in deep leagues heading into this matchup.

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Detroit Lions wide receiver Kalif Raymond (ankle) missed his second practice of the week on Tuesday due to an ankle injury, according to Eric Woodyard of ESPN. It's looking like Raymond won't be able to play on Thanksgiving Day on Thursday when the division-rival Green Bay Packers come to town after he hurt his ankle in Sunday's overtime victory over the New York Giants. If he is unable to practice on Wednesday, Raymond will almost certainly be ruled out for Week 13, which would open up more snaps for rookie third-rounder Isaac TeSlaa. The 31-year-old Raymond has had a limited role in Detroit's offense in his fifth year with the team, catching only 15 of 19 targets for 150 yards and no touchdowns in 11 games played. He caught both of his targets in Week 12 for 37 yards, his second-best yardage output of the year.

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Detroit Lions rookie wide receiver Isaac TeSlaa (hand) is dealing with a hand injury and has been limited in practice on Monday and Tuesday, according to ESPN's Eric Woodyard. TeSlaa only has four receptions in 11 games played in his first NFL season, but two of those grabs came in the end zone for Detroit. The 23-year-old third-rounder out of Arkansas has played through an oblique issue recently as well, but he should be good to go for Thursday's Thanksgiving Day tilt against the division-rival Green Bay Packers in Week 13. Fellow wideout Kalif Raymond (ankle) is in danger of being inactive after two missed practices already this week, so it's possible that TeSlaa could have an expanded role for the Lions. Still, TeSlaa would be an incredibly risky fantasy option. He hasn't caught a pass since Nov. 9 and hasn't seen more than two looks in a game in 2025.

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Green Bay Packers wide receiver Dontayvion Wicks (calf) continues to be limited at practice for the second straight day this week on Tuesday due to an ongoing calf issue, according to Eric Woodyard of ESPN. Wicks has been on the team's injury report for the last three weeks with a calf injury, but he has managed to play through it. The 24-year-old should be out there again this Thursday on Thanksgiving Day against the division-rival Detroit Lions, but he's purely a deep-league dart throw, at best. That will be especially true if both Jayden Reed (foot, shoulder) and rookie Matthew Golden (wrist) return from their injuries this week. Wicks scored nine times in his first two years in the NFL with Green Bay, but he's still searching for his first touchdown through 12 weeks of the 2025 season. He has 20 catches for 213 yards on 34 targets in nine games.

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Detroit Lions tight end Brock Wright (neck) injured his neck in Sunday's overtime win over the New York Giants and has missed two practices this week. Wright will probably need to practice in some capacity on Wednesday to avoid being ruled out entirely. With Sam LaPorta (back) going on Injured Reserve, Wright has operated as the team's top pass-catching tight end the last two weeks, but it has amounted to only five catches for 37 yards on 11 targets. If the 26-year-old is ruled out for Thursday's game versus the division-rival Green Bay Packers, Ross Dwelley figures to see an expanded role for Detroit at the TE position. Fantasy managers should be looking for better and healthier streaming options at tight end in Week 13. Wright is currently rostered in only 2% of Yahoo leagues.

From RotoBaller

Detroit Lions C Graham Glasgow (knee), S Kerby Joseph (knee), DE Josh Paschal (back), WR Kalif Raymond (ankle), and TE Brock Wright (neck) did not practice on Tuesday, Nov. 25. CB Terrion Arnold (concussion), OT Taylor Decker (shoulder), G Tate Ratledge (knee), RB Jacob Saylors (back, shoulder), OT Penei Sewell (ankle), WR Isaac TeSlaa (hand), and RB Sione Vaki (ankle, thumb) were limited in practice on Tuesday. DB Brian Branch (toe, ankle), DE Marcus Davenport (shoulder), and OL Miles Frazier (knee) practiced in full on Friday.

From TheHuddle

Green Bay Packers rookie first-round wide receiver Matthew Golden (wrist) was limited in practice for the second straight day this week on Tuesday with a wrist injury, according to Eric Woodyard of ESPN. Golden missed Sunday's decisive win over the Minnesota Vikings at Lambeau Field with shoulder and wrist injuries. The 22-year-old Texas product is tracking towards returning on Thanksgiving Day on Thursday against the division-rival Detroit Lions, though, now that he's clear of his shoulder injury. Golden probably needs to practice in full on Wednesday to avoid taking another questionable tag into game day. Fantasy managers who bought into the preseason hype surrounding Golden have been disappointed so far in 2025, as he's caught just 24 passes for 286 yards on 32 targets. He's still searching for the first touchdown of his career, and his chances of contributing down the stretch aren't going to get any better now that Jayden Reed (foot, shoulder) is nearing a return.

From RotoBaller

Green Bay Packers wide receiver Jayden Reed (foot, shoulder) was listed as limited again in practice on Tuesday, per ESPN's Eric Woodyard. Reed returned to practice last Friday for the first time since breaking his collarbone in Week 2. The 25-year-old is also recovering from surgery for a Jones fracture in his foot. Reed will probably need to upgrade to a full practice on Wednesday for the Packers to even consider officially activating him from Injured Reserve to play on Thanksgiving on Thursday against the division-rival Detroit Lions. He's a stash candidate in most fantasy leagues, but even if Reed were to play on Turkey Day, he wouldn't be a recommended starting lineup option in his first game back after a long layoff. The most likely scenario is that Green Bay holds Reed out until their Week 14 divisional matchup against the Chicago Bears on Sunday, Dec. 7.

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Atlanta Falcons running back Bijan Robinson had a solid, albeit unspectacular, fantasy day in Sunday's 24-10 win over the Saints. The 23-year-old rushed14 times for 70 yards and caught both of his targets for an additional 37 yards. He was unable to find the end zone, though, as wide receivers Darnell Mooney and David Sills V each caught the Falcons' only two touchdowns on the day. While the rushing yardage was good, averaging five yards per carry, the number of targets was disappointing. Two of his lowest target totals this season have come in the two games with Kirk Cousins under center, averaging 2.5 targets per game, comparedto 5.1 targets per game in the nine games with Michael Penix Jr. (knee) at the helm. It was disappointingenough that Tyler Allgeier was vulturing touchdowns, but now it seems his work in the passing attack will also take a hit with the QB change. The third-year pro is one of the most explosive and talented backs in the league, but his fantasy floor appears to be lower than it was earlier this season. Even so, he'll likely remain a top option at running back in Week 13 when the Falcons go on the road to visit the Jets, a defense that has yielded the ninth-most fantasy points to opposing running backs this season.

From RotoBaller

Green Bay Packers running back Josh Jacobs (knee) missed his first game of the year in the Week 12 win over the Minnesota Vikings due to a knee contusion, and he should be considered questionable for the Week 13 divisional clash against the Detroit Lions on Thursday on Thanksgiving Day after being listed as limited for the team's first two practices of the week on Monday and Tuesday. The 27-year-old's injury isn't considered serious, but the Packers could play it safe with their star RB on a short week. Jacobs may need to upgrade to a full practice on Wednesday to avoid a questionable tag going into Thursday's game. He has been a must-start RB1 in fantasy football with 11 touchdowns in 10 games this year, but fantasy managers could be without him for a second straight game. If Jacobs is out again in Week 13, Emanuel Wilson will be a plug-and-play RB2 again after scoring twice and rushing for over 100 yards on Sunday.

From RotoBaller