Arizona Cardinals wide receiver Michael Wilson remains atop the depth chart after Marvin Harrison Jr. (appendix) was ruled out for Sunday's Week 12 contest against the Jacksonville Jaguars. This will be Wilson's second consecutive game as the top wide receiver in Arizona. He dominated last week's contest, catching a whopping 15 of 18 targets for 185 yards. Quarterback Jacoby Brissett set the NFL's all-time single-game completion record in that outing, so perhaps Wilson's volume will drop a little in Week 12. Still, he's a strong candidate to fetch double-digit targets. He'll also have a decent chance to score his first touchdown since Week 2, especially against a Jaguars defense allowing the eighth-most touchdowns to wide receivers in 2025. Wilson is a strong fantasy starter in most leagues on Sunday, checking in as the overall WR18 in RotoBaller's latest Week 12 fantasy rankings.

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Cincinnati Bengals quarterback Joe Flacco will get one more opportunity to start after Joe Burrow (toe) was ruled out for Sunday's Week 12 contest against the New England Patriots. While Burrow was trending in the right direction for this week, the Bengals have ultimately decided to keep him on injured reserve for at least a few more days. As a result, Flacco will remain installed as Cincinnati's starting quarterback for Week 12. He's coming off an uninspiring 199-yard clunker against the Steelers, and although he has five touchdowns over his last two games, he also has four turnovers during that span. To make matters worse, he'll be without Ja'Marr Chase (suspension), shifting Tee Higgins to the top receiver role. New England's defense has been strong this season, but it's best at stopping the run. The Patriots have allowed the ninth-most passing yards, seventh-most passing touchdowns, and 12th-most fantasy points to opposing quarterbacks in 2025. This matchup and situation are best defined as "good, not great." That sentiment is reflected in RotoBaller's ranking of Burrow as the overall QB17 this week.

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Jacksonville Jaguars running back Bhayshul Tuten (ankle) has been cleared to play in Sunday's Week 12 contest against the Arizona Cardinals, and he'll have a terrific opportunity to build on last weekend's career-best outing. It's common for rookies to get more involved in the weeks following their team's bye, and that's exactly what we saw from Tuten. In his third game post-bye week last Sunday, the Virginia Tech product rushed 15 times for 74 yards and a touchdown, and he would have earned even more touches if he hadn't left early due to injury. Tuten and Travis Etienne Jr. showed that they can co-exist productively, and that the Jaguars' offense is at its best when they're running the ball effectively. Even with Etienne still in the mix, Tuten should be able to carve out a significant role again this Sunday. The Jaguars could go run-heavy with Travis Hunter (knee) and Brian Thomas Jr. (ankle) sidelined, and they should take advantage of a Cardinals defense allowing the 11th-most fantasy points and fourth-most rushing touchdowns to opposing running backs in 2025. Tuten ranks as the RB30 in this week's RotoBaller fantasy rankings, and he should be started in most leagues with 12 or more teams.

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Atlanta Falcons wide receiver Darnell Mooney will jump to the top of the depth chart after teammate Drake London (knee) was ruled out for Sunday's Week 12 contest against the New Orleans Saints. Even as the de facto No. 1 receiver, Mooney's productivity isn't guaranteed. In the other game that London missed earlier this season, Mooney caught just one of four targets for 11 yards. With that said, there's optimism that this week's increased workload will lead to better results. After all, he's already trending up with 15 targets over his last two games. Plus, he gets a softer matchup against the Saints, who rank near the middle of the league in fantasy points and have allowed the eighth-most touchdowns to opposing receivers in 2025. This week, Mooney will be catching passes from Kirk Cousins, since Michael Penix Jr. (knee) is on injured reserve. The veteran receiver's game was elevated with Cousins under center last year, as the veteran signal-caller was responsible for most of Mooney's volume and yardage during his 64-catch, 992-yard campaign in 2024. Managers should feel comfortable starting the 28-year-old as a WR3/flex this week. He ranks as the overall WR26 in RotoBaller's latest fantasy rankings for Week 12.

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Kansas City Chiefs running back Kareem Hunt will earn another start after Isiah Pacheco (knee) was ruled out for Sunday's Week 12 game against the Indianapolis Colts. Pacheco is on track to miss his third consecutive game. In each of his two previous absences, Hunt took over as the primary running back, logging at least a 79% snap share on both occasions. He's averaging 12 carries, 54 rushing yards, one reception, 4.5 receiving yards, and one touchdown in games he's started with Pacheco sidelined. The veteran running back should handle around 10-15 touches once again this Sunday against the Colts. Indianapolis has been effective against the run, allowing the seventh-fewest rushing yards and 10th-fewest fantasy points to opposing running backs in 2025. Despite the tougher matchup, Hunt's role and volume have vaulted him up to the RB25 spot in this week's RotoBaller fantasy rankings.

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Jacksonville Jaguars tight end Brenton Strange (hip) should carve out a significant workload in his return from injury during Sunday's Week 12 contest against the Arizona Cardinals. Strange is still listed as questionable for the game, but his activation from injured reserve on Saturday indicates that he will play. The 24-year-old's return comes at a convenient time for the Jaguars, who are without both Travis Hunter (knee) and Brian Thomas Jr. (ankle). Hunter is done for the season, while Thomas' injury is expected to be more temporary. Strange figures to operate as one of Trevor Lawrence's favorite targets alongside Jakobi Meyers and Parker Washington. Strange impressed earlier this season, catching 19 of 22 targets for 182 yards during the three games for which he was healthy. He should waste no time returning to this sizable target share on Sunday against the Cardinals, who have allowed the 12th-most fantasy points and ninth-most touchdowns to opposing tight ends in 2025.

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New York Jets wide receiver John Metchie III could see more work in the receiving game going forward. The Jets are looking for someone to step up and be a playmaker with Garrett Wilson (knee) still sidelined. Last week, Metchie hauled in all three of his targets for 45 yards and a touchdown in the loss to the New England Patriots. Given his success, Metchie could be asked to take on more responsibility in the receiving game this weekend. It's worth noting that Adonai Mitchell saw six targets last week, so he'll likely profile as the top target in Week 12. Despite that, Metchie should see enough of a workload to offer low-end flex value for the upcoming matchup against the Baltimore Ravens.

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Arizona Cardinals wide receiver Greg Dortch should once again see an expanded role in the receiving game this weekend. Fellow wideout Marvin Harrison Jr. (appendix) has been ruled out for a second straight game. Last week, Dortch hauled in all six of his targets for 66 yards and a touchdown in the loss to the San Francisco 49ers. Prior to that, Dortch went two straight games without a catch. That being said, Dortch doesn't seem to carry much long-term value, but is worth a look while Harrison is out. Given his success last week, Dortch should once again see a good volume in the passing game. He'll get a favorable matchup against the Jacksonville Jaguars defense that has struggled to contain the passing game. Dortch should be viewed as a flex option for this weekend.

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Tampa Bay Buccaneers running back Sean Tucker is coming off a fantastic performance against the Buffalo Bills. Last week, Tucker rushed 19 times for 106 yards and scored two touchdowns in the loss. He also hauled in two receptions for 34 yards and an additional score through the air. All signs are pointing to Tucker once again having a large role in the backfield during the Week 12 matchup against the Los Angeles Rams. Lead back Bucky Irving (shoulder, toe) remains out for at least one more week. Tucker seems to have the edge over Rachaad White after that 100-plus yard performance. The expectation is that Tucker sees enough snaps to warrant high-end RB3 value for this weekend.

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Cincinnati Bengals wide receiver Andrei Iosivas is expected to have a larger role in the receiving game this weekend Fellow wideout Ja'Marr Chase is unavailable due to a suspension, but should return against the Baltimore Ravens for the Thanksgiving game. In the meantime, Iosivas should slide up the depth chart with Chase unable to suit up. Iosivas has been a non-factor in the offense outside of two five-catch performances. The 26-year-old showed good potential last season when he hauled in six touchdowns across 17 games. Iosivas is unlikely to carry much long-term value with Chase returning next week. However, fantasy managers should be able to plug him in as a low-end WR3 for this weekend.

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New England Patriots running back Rhamondre Stevenson (toe) currently carries a questionable tag into Sunday's Week 12 matchup against the Cincinnati Bengals. Stevenson has missed the last three games, but is expected to play this weekend. It's unclear how the backfield snaps will be split up once Stevenson does return. TreVeyon Henderson has scored five touchdowns since Stevenson went down. The rookie back figures to have earned a larger role going forward. Stevenson is likely only going to offer flex appeal in what could be closer to a 50/50 split in the backfield going forward.

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Pittsburgh Steelers quarterback Aaron Rodgers (wrist) remains uncertain to suit up ahead of the Week 12 matchup against the Chicago Bears. Rodgers is dealing with a minor fracture on his left (non-throwing) wrist. The veteran quarterback has been pushing to play, but the organization seems more cautious. It sounds like if the decision is left up to Rodgers then he'll suit up. Otherwise, fantasy managers might need to find another option for Sunday's slate. Mason Rudolph would be in line to start if Rodgers is ruled out. Fantasy managers should check back for another update on Rodgers.

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NFL Network's Ian Rapoport reports that Kansas City Chiefs wide receiver Xavier Worthy (ankle) is expected to play in Sunday's home matchup with the Indianapolis Colts. Worthy picked up an ankle injury mid-week during the team's preparations for a game against the Broncos in Week 11, but carried no designation into the contest. After missing practice on Wednesday, the second-year pro was able to upgrade his status each ensuing day, and appears to be on the right side of questionable heading into a juicy outing against an exploitable Colts' pass defense. As it stands, fantasy managers can expect him to be out there for his usual allotment of snaps. Worthy profiles as a solid WR3 play in a game with a 50.5-point over/under.

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According to ESPN's Adam Schefter, the New Orleans Saints expect running back Alvin Kamara (ankle) to be available for Sunday's meeting with the visiting Atlanta Falcons. Kamara has battled an ankle injury for a large portion of the 2025 campaign. Despite being labeled as questionable for the past few games, he's yet to miss one because of it. The 30-year-old put together one of his better performances of the season before New Orleans went on bye in Week 11, eclipsing 100 scrimmage yards for the first time since Week 2, and showed well against a decent Carolina run defense. If, for whatever reason, the veteran is unable to suit up in Week 12, teammates Devin Neal and Audric Estime would man the backfield in his stead.

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Seattle Seahawks running back Kenneth Walker III (glute) is expected to play in Week 12's road matchup with the Tennessee Titans. ESPN's Adam Schefter reported the news. The Michigan State product was a late addition to Seattle's practice report on Friday, logging a limited session with a glute issue that forced the team to deem him questionable. However, head coach Mike Macdonald has expressed that the move was precautionary, and he should be fine for Sunday. It's excellent news for him, as Walker III is in a smash spot against a Titan's defense that's yielded the seventh-most rushing yards (134.7) and eighth-most fantasy points per game to running backs (24.35). Fantasy managers will still want to remain watchful of the 25-year-old's official game-time status, although he doesn't appear to be in any danger of missing his first appearance this season.

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Tampa Bay Buccaneers wide receiver Chris Godwin (leg) is anticipated to have his snap count limited for Sunday's road matchup with the Los Angeles Rams, according to Jeremy Fowler of ESPN. Fowler notes that the Pennsylvania native "will likely be on something of a pitch count," as the team manages his reps following a five-game layoff. It makes sense that Tampa Bay would be cautious with the veteran's playing time, considering he's only appeared in two games thus far while working back from ankle and fibula injuries. For this week at least, teammates Tez Johnson and Sterling Shepard will run behind Emeka Egbuka for the majority of snaps. If everything goes to plan, one, if not both, Johnson and Shepard would see a decrease in playing time moving forward as Godwin puts time between him and his injury. He's a shaky play in his first game back.

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ESPN's Adam Schefter reports that the Tampa Bay Buccaneers expect running back Bucky Irving (foot, shoulder) to make his return to the field for next Sunday's home game with the Arizona Cardinals. The second-year pro logged three more limited practices as he returns to health, but was ultimately ruled out a seventh straight time for their clash with the Rams. Per Schefter, Irving "looked strong at practice this week," and might have been able to suit up for Week 12's contest. Alas, Tampa Bay will afford him a few more days to get right as they gear up for a playoff push. Teammates Rachaad White and Sean Tucker are poised for another week splitting backfield work in his stead, though it will be interesting to see whether last week's distribution was fluky or a trend.

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Tampa Bay Buccaneers kicker Chase McLaughlin nailed both of his short field goal attempts and two extra points in a Week 11 loss to the Buffalo Bills. McLaughlin has been money again for the Bucs in his third season with the team, making 20 of 24 attempts and 20 of 21 extra points. The 29-year-old has arguably been the best kicker in the league from deep range, making all eight attempts from 50 yards or more and owning the second-longest kick of the season at 65 yards back in Week 4 against the Philadelphia Eagles. McLaughlin ranks as the No. 6 overall kicker in fantasy points scored this season and is a strong option in a dome on Sunday Night Football against the Los Angeles Rams. He is RotoBaller's 11th-ranked kicker for Week 12.

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Jacksonville Jaguars kicker Cam Little didn't attempt a field goal for the first time this season in last week's 35-6 win over the Los Angeles Chargers, but nailed all five extra points. Little has been a solid kicker option this season for fantasy managers, making 16 of 20 attempts and 24 of 25 extra points, ranking as the No. 15 kicker in total fantasy points. His 80% field goal percentage is just below the league average of 84.5%. The 22-year-old has one of the strongest legs in the league, as displayed by his 70-yard kick in the preseason, and he made history in Week 9 against the Raiders with the longest kick of all time at 68 yards. Little is RotoBaller's seventh-ranked kicker for Week 12 against the Arizona Cardinals.

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Dallas Cowboys kicker Brandon Aubrey has only attempted three field goals in the past three games, which has limited his scoring for fantasy, but he is still one of the few must-start kicker options every week. Aubrey ranks as the No. 4 overall kicker in points scored this season, making 18 of 19 attempts and 32 of 33 extra points. The 30-year-old made the third-longest kick of the season at 64 yards back in Week 4 and is one of only six kickers in the league to make a kick of 60 yards or more. Aubrey is a must-start option in Week 12 against the Philadelphia Eagles, who he had 11 fantasy points against back in Week 1.

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