New York Giants wide receiver Darius Slayton (hamstring) missed the first practice of the week on Wednesday, according to Dan Salomone of Giants.com. Slayton suffered a hamstring injury in the Week 5 loss to the New Orleans Saints and didn't practice on a short week before missing last Thursday night's upset win over the Philadelphia Eagles. Another DNP to begin Week 7 preparation is a bad sign, but Slayton still has two more days to get back onto the practice field. If the 28-year-old cannot do so, he'll miss a second straight game this Sunday versus the Denver Broncos on the road. Slayton figures to be one of New York's top pass-catchers the rest of the year now that Malik Nabers (knee) is done for the season, but he needs to get healthy first. If Slayton gets cleared to play on Sunday, he'll be a WR4/flex, at best, against a stingy Denver defense.

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Indianapolis Colts wide receiver Josh Downs (concussion) is in the league's concussion protocol this week, according to Stephen Holder of ESPN. Fellow wideout Ashton Dulin (chest) also missed practice on Wednesday with a chest injury. Downs had a strong game in the Week 6 win over the Arizona Cardinals, catching six of his seven targets for 42 yards and a touchdown, but he could be forced to miss a Week 7 contest on the road against the Los Angeles Chargers unless he's cleared from the concussion protocol later this week. If Downs is unavailable this weekend, Adonai Mitchell could be active once again as WR depth after being a healthy scratch last Sunday. Alec Pierce would be elevated to the WR2 role behind Michael Pittman Jr. and would be in play as a WR4/flex in fantasy lineups. In the last two games, Downs has come on strong, catching 12 total passes (15 targets) for 96 yards and a score.

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Carolina Panthers head coach Dave Canales wouldn't say for sure if running back Rico Dowdle will start on Sunday at RB against the New York Jets, but would only say that Dowdle "has earned the right to help this team and we will find a way (for him) to do that." Chuba Hubbard (calf) has missed the last two games, and in that time, Dowdle has amassed more than 400 scrimmage yards and two touchdowns on 60 total touches. At the very least, the 27-year-old has earned a backfield split with Hubbard, who could return this weekend after practicing on Wednesday for the first time since Week 4. Before Hubbard's injury, he was solid in his own right as the Panthers' starting RB. It's a good problem to have for Carolina. If Hubbard is back in Week 7, the backfield touches figure to be split more evenly, making things more cloudy for fantasy managers.

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Las Vegas Raiders running back Ashton Jeanty recorded a season-high 23 rush attempts for 75 yards and a touchdown in their 20-10 win over the Titans in Week 6. Head coach Pete Carroll spoke on Wednesday regarding the workload for his star rookie running back and said that he hopes that is the norm for him moving forward. Jeanty has topped 20 carries twice this season, including a career-high performance in Week 4 against the Bears, when he rushed for 138 yards and scored three total touchdowns. He hasn't been very efficient running behind a poor run-blocking offensive line, but his touch volume ranks among the highest at the position. Jeanty will rank as a low-end RB1 in Week 7 against the Chiefs.

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Kansas City Chiefs wide receiver Rashee Rice's six-game suspension is over, and he will make his 2025 debut in the Week 7 divisional clash against the Las Vegas Raiders this Sunday. "He's going to play (Sunday against the Raiders). How many snaps he'll get, (I don't know). He's been working hard. He's in good shape," head coach Andy Reid said. Rice is practicing with the rest of the team for the first time this year on Wednesday. According to ESPN's Jeremy Fowler, the Chiefs "will be allocating a heavy workload for him as soon as possible," so fantasy managers will want to get Rice back into their starting lineups immediately in a good matchup. In addition to his six-game suspension, the 25-year-old is back from an LCL tear in his knee that he suffered in the offseason. When fully healthy, Rice is expected to be quarterback Patrick Mahomes' favorite target.

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Carolina Panthers tight end Ja'Tavion Sanders (ankle) was listed as limited in the team's Wednesday practice report. Sanders has missed three straight games as he continues to nurse an ankle issue, but he is trending in the right direction with a practice to begin the week. Sanders was productive in the three games he played, catching 11 of 14 targets for 92 yards. If he's unable to go again in Week 7, the tight end snaps will be mixed again between Tommy Tremble, Mitchell Evans, and James Mitchell.

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Carolina Panthers wide receiver Jalen Coker (quadriceps) was a full participant in practice on Wednesday. Coker was apparently "really close" to returning to the field in Week 6 against the Cowboys, according to head coach Dave Canales, but the team opted to give him another week. His practice window was opened, and he practiced in full every day in practice last week, which should give him a good chance at making his season debut in Week 7 against the Jets. The 23-year-old could slide in immediately as the No. 2 wide receiver behind star rookie Tetairoa McMillan, as no other Carolina pass catcher has emerged. Coker is a worthwhile pickup off the waiver wire in 12-team leagues where available.

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Los Angeles Chargers wide receiver Quentin Johnston (hamstring) will participate in practice on Wednesday, according to Kris Rihm of ESPN. Johnston missed his first game of the season against Miami in Week 6, but looks to be on the right track to return in Week 7, although he was limited in practice throughout last week and ultimately didn't suit up. Johnston has had a fantastic start to his third season through five games, racking up 26 catches on 40 targets for 377yards and four touchdowns. The 24-year-old leads the team in receiving yards and touchdowns, even with missing one game. His status for Week 7 against Indianapolis should become clearer as the week goes on.

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Tennessee Titans wide receiver Calvin Ridley (hamstring) was not spotted at practice on Wednesday, according to Jim Wyatt of TennesseeTitans.com. Ridley played only six offensive snaps in the Week 6 loss to the Las Vegas Raiders on Sunday before injuring his hamstring and never returning. The 30-year-old is on the wrong side of questionable early in the week after not practicing on Wednesday, but he still has two more days to get back on the practice field. If he is unable to go this weekend against the New England Patriots, rookie wideout Elic Ayomanor should operate as the Titans' No. 1 receiver. Veteran Van Jefferson would also be in line for an expanded role for the second straight week. Ridley has had a very disappointing 2025 campaign to this point, catching 16 passes for 290 yards in six games. He's still searching for his first touchdown.

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Updating a previous report, Carolina Panthers running back Chuba Hubbard (calf) was officially a limited participant in his return to practice on Wednesday, according to David Newton of ESPN. This is the first time that Hubbard has practiced since injuring his calf in Week 4. The 26-year-old missed Weeks 5 and 6 and left backfield duties to Rico Dowdle, who took full advantage of the elevated role to go for 473 scrimmage yards and two touchdowns on 60 touchdowns over that span. Dowdle's domination has allowed the Panthers to slow-play Hubbard's return, but it looks like he could make it back this Sunday against the New York Jets. Carolina has said that it will be more of an even split in the backfield between Hubbard and Dowdle when Hubbard returns, which will lower the fantasy ceilings of both RBs. Dowdle could see more work in Week 7 if Hubbard is eased back into the offense this weekend.

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Los Angeles Rams head coach Sean McVay said that running back Blake Corum (ankle) will not practice on Wednesday, according to Stu Jackson. Corum suffered an ankle injury in Sunday's Week 6 win over the Baltimore Ravens and is now in danger of missing the Week 7 game in London on Sunday against the Jacksonville Jaguars. The 24-year-old is considered day-to-day for now after being able to return to the field on Sunday in Baltimore after initially injuring his ankle. Corum has not had any standalone fantasy value this year while working as Kyren Williams' backup, so even if he's cleared to play this weekend, he should stay on your bench. If Corum doesn't get cleared to play overseas on Sunday, rookie Jarquez Hunter would take on an elevated role as the change-of-pace back behind Williams.

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Los Angeles Rams head coach Sean McVay said that wide receiver Tutu Atwell (hamstring) will be limited in Wednesday's practice, per Stu Jackson. Atwell missed the Week 6 win over the Baltimore Ravens due to a knee injury, but the 26-year-old is on the right track to make his return in London this Sunday against the Jacksonville Jaguars. It couldn't come at a better time for the Rams, either, with star wideout Puka Nacua (ankle) up in the air to play due to an ankle injury that he suffered on Sunday. The Rams have been optimistic about Atwell playing this weekend, but he might need to get in a full practice on Thursday or Friday to avoid taking a questionable designation into the weekend. Atwell could see more playing time if he returns to the fold against the Jags, but he'll only be in consideration as a deep-league flex play if Nacua is inactive.

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Los Angeles Rams head coach Sean McVay said that wide receiver Puka Nacua (ankle) will not practice on Wednesday, according to Sarah Barshop of ESPN. Nacua is being considered day-to-day after injuring his left ankle in the team's Week 6 win over the Baltimore Ravens, but he is firmly up in the air to play in London in Week 7 versus the Jacksonville Jaguars. The fact that the 24-year-old isn't practicing on Wednesday is not a great sign, but he still has two days to get back on the field. It seems more likely that the Rams will hold the star wideout out of this weekend's game, with their bye coming in Week 8. We will continue to closely monitor Nacua's status, but fantasy managers should be preparing as if he won't suit up for their international game. If Nacua is out, Davante Adams will operate as the WR1, with Jordan Whittington and Tutu Atwell (hamstring) seeing an uptick in targets, too.

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Carolina Panthers running back Chuba Hubbard (calf) returned to practice Wednesday after missing the past two games. During his absence, Rico Dowdle has impressed, which could impact the backfield rotation moving forward. Earlier in the season, Hubbard held a near two-to-one edge in snaps over Dowdle, but that split may narrow as the coaching staff rewards Dowdle's recent success. While Hubbard's return will cut into Dowdle's fantasy value, both backs could remain involved against a vulnerable Jets run defense that ranks 23rd in the league, allowing 130 rushing yards per game. Fantasy managers should monitor practice reports this week to see how Carolina plans to divide touches ahead of Sunday's matchup.

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Green Bay Packers wide receiver Dontayvion Wicks (ankle) returned to practice Wednesday after exiting Week 6 early. The 24-year-old has recorded 12 receptions for 129 yards this season and could be in line for more work if healthy heading into Sunday's matchup with Arizona. However, Wicks may face added competition for targets following Matthew Golden's breakout performance last week. The Packers' passing game draws a favorable matchup against a Cardinals defense ranked 28th against the pass, giving Wicks some deep-league streaming appeal if he's active. Fantasy managers should continue monitoring his practice participation as the week progresses.

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Pittsburgh Steelers wide receiver Calvin Austin III (shoulder) has been ruled out for Thursday night's matchup against the Cincinnati Bengals, marking his second straight missed game. Before suffering the injury, Austin had started all four contests, recording 10 receptions on 17 targets for 139 yards and two touchdowns. In his absence, tight end Darnell Washington has seen an increased target share, while D.K. Metcalf continues to build strong chemistry with quarterback Aaron Rodgers. The Steelers will face a favorable matchup against a Bengals defense ranked 31st overall, giving their passing attack an opportunity to stay productive even without Austin on the field.

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Jacksonville Jaguars head coach Liam Coen stated the team plans to expand rookie wide receiver Travis Hunter's role moving forward, utilizing his elite speed and athleticism more frequently within the offense. The second overall pick has caught 20 of 31 targets for 197 yards but has yet to find the end zone in his debut season. Despite early frustrations for fantasy managers, Coen's comments suggest an uptick in volume could be coming soon. Hunter's versatility as both a wide receiver and cornerback makes him one of the league's most dynamic young players, and additional touches could quickly boost his fantasy value. Managers in deeper leagues may want to hold tight, as Hunter's breakout could be on the horizon.

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Dallas Cowboys owner Jerry Jones said linebacker DeMarvion Overshown (knee) could return to action following the team's bye week on November 9. Overshown has been sidelined since tearing his ACL, MCL, and PCL in December 2024 but has made steady progress in his recovery. Before the injury, the former third-round pick led the Cowboys with 90 tackles in 13 games and showcased elite athleticism throughout his rookie campaign. Jones' update suggests the team is targeting a cautious return timeline to ensure Overshown is fully ready for the stretch run. His eventual return would provide a major boost to a Dallas defense that's been inconsistent and thin at linebacker depth this season after trading Micah Parsons.

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Dallas Cowboys wide receiver KaVontae Turpin (foot) returned to practice on Wednesday after missing the past two games with a foot sprain. Turpin has quietly been efficient this season, hauling in 11 of 13 targets for 159 yards and a touchdown. While he's not a focal point of the Dallas passing attack, his speed and versatility keep him involved enough to offer deep-league or bye-week appeal. With the Cowboys offense passing at a high volume, Turpin could provide sneaky flex value if he's cleared to play in Week 7. Fantasy managers should keep an eye on his practice participation throughout the week before considering him as a potential plug-in option.

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Dallas Cowboys wide receiver CeeDee Lamb (ankle) returned to practice on Wednesday, opening the possibility to suit up for Sunday's divisional clash with the Washington Commanders. Lamb has missed the past three games, opening the door for George Pickens to take on a larger role in the passing game. His potential return comes at the perfect time, as the Commanders rank just 23rd against the pass and have struggled to contain top receivers all season. If active, Lamb immediately resumes his role as a must-start WR1 and should provide a significant boost to Dak Prescott's fantasy outlook as well.

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