Green Bay Packers running back Josh Jacobs (knee) missed his first game of the year in the Week 12 win over the Minnesota Vikings due to a knee contusion, and he should be considered questionable for the Week 13 divisional clash against the Detroit Lions on Thursday on Thanksgiving Day after being listed as limited for the team's first two practices of the week on Monday and Tuesday. The 27-year-old's injury isn't considered serious, but the Packers could play it safe with their star RB on a short week. Jacobs may need to upgrade to a full practice on Wednesday to avoid a questionable tag going into Thursday's game. He has been a must-start RB1 in fantasy football with 11 touchdowns in 10 games this year, but fantasy managers could be without him for a second straight game. If Jacobs is out again in Week 13, Emanuel Wilson will be a plug-and-play RB2 again after scoring twice and rushing for over 100 yards on Sunday.

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Dallas Cowboys wide receiver George Pickens (calf, knee) was officially listed as limited at Tuesday's practice, according to Jon Machota of The Athletic. Pickens was estimated as a non-participant on Monday, so it's an upgrade for the 24-year-old's status heading into Thursday's Thanksgiving Day game against the visiting Kansas City Chiefs in Week 13. Pickens is a little banged up with multiple injuries, but he's fully expected to play this week and should remain locked into all fantasy football lineups as Dallas' No. 1 wideout in 2025. Pickens brings a 67-1,054-8 line into Thursday's game on 92 targets in his first year with the Cowboys. The matchup against the Chiefs is not ideal, but Pickens is a must-start as the WR2 in half-PPR scoring this year.

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Dallas Cowboys wide receiver KaVontae Turpin (illness, shoulder) was back at practice on a limited basis on Tuesday due to an illness and a shoulder injury, per The Athletic's Jon Machota. Turpin's return to the practice field on Tuesday after being a DNP on Monday is a sign that he's trending towards being available on Thanksgiving on Thursday versus the Kansas City Chiefs. The 29-year-old caught one pass for a 48-yard pickup on two targets in Sunday's win over the Philadelphia Eagles. Turpin is more of an asset for Dallas as a kick returner on special teams. He has not caught more than two passes in a game since Sept. 28 against the Green Bay Packers, and his only score on offense in 2025 came back on Sept. 14 versus the New York Giants. If active on Thursday against KC, Turpin isn't a realistic starting option in fantasy football lineups.

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Kansas City Chiefs wide receiver Rashee Rice (hamstring) practiced in full capacity on Tuesday, Jon Machota of The Athletic reports. Rice was upgraded to a full participant after being estimated as limited in Monday's walk-through. The 25-year-old tweaked his hamstring during Kansas City's Week 12 win over the Colts and had his lowest snap share in a game (62.5%) since returning from suspension in Week 7, but it didn't stop him from posting a career high 141 yards and the first 100-yard game by a Chief this season. The injury shouldn't concern any fantasy managers after a full practice on Tuesday, and Rice should feast again in a potential shootout against the Dallas Cowboys on Thanksgiving.

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Kansas City Chiefs wide receiver Xavier Worthy (ankle) was listed as a full participant in Tuesday's practice session, according to Jon Machota of The Athletic. Worthy was estimated as limited in Monday's walk-through, but was upgraded to full on Tuesday and should be all good to go for Kansas City's Week 13 matchup against the Dallas Cowboys on Thanksgiving. The second-year wideout recorded four catches for 59 yards on eight targets in the Chiefs' win over the Colts in Week 12, his most yards in a game since Week 4 against the Ravens. Worthy made one of the biggest plays of the game on the Chiefs' final drive to set up the game-winning field goal, beating his man deep for a 31-yard gain on a third down. He has a great matchup against the Cowboys in Week 13, where he will again rank in the WR3 range.

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The Buffalo Bills have signed former New Orleans Saints wide receiver Brandin Cooks to their active roster, according to Adam Schefter of ESPN. Cooks played 10 games for the Saints this season before reaching an agreement with the team to be released on November 22. The former first-round pick in 2014 cleared waivers and had the option to sign anywhere, ultimately choosing to sign with the contending Bills, who need wide receiver help. The 12-year veteran didn't show much in his time with the Saints this season, catching 19 of his 25 targets for 165 yards and no touchdowns, but he should have a chance to immediately contribute in Buffalo.

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Cleveland Browns rookie running back Dylan Sampson had arguably the best game of his career in Week 12's win over the Las Vegas Raiders, handling seven carries for 23 yards with two receptions (three targets) for 59 yards and a touchdown. It was Sampson's second career touchdown; his first also came on a reception back in Week 2, and he posted his second-most yards from scrimmage in a game, trailing only his 93-yard performance in Week 1. The rookie fourth-rounder totaled 27 touches in the first two weeks, but his role in Cleveland's offense decreased after fellow rookie Quinshon Judkins returned to the team in Week 2. From Weeks 3 through 11, Sampson played just 18.7% of the snaps with 25 total touches. He was dynamic in Cleveland's Week 12 win, however, taking a simple screen pass from Shedeur Sanders 66 yards for a touchdown. Judkins is still the clear lead back, but Sampson's pass-catching ability could make him fantasy viable in deeper PPR leagues moving forward.

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Philadelphia Eagles running back Tank Bigsby has settled in as the team's RB2 behind starter Saquon Barkley. However, that doesn't mean the 24-year-old former Jaguars RB should be rostered in 12-team fantasy leagues for the time being. Bigsby played only three offensive snaps in Sunday's loss to the Dallas Cowboys and had one carry for eight yards. In his 10 games since joining the Eagles this year, Bigsby has only 18 carries for 164 yards in a backup role. Philly's offense has been sluggish, too, which hasn't helped Bigsby's cause for more work in a complementary role. Going into a Week 13 game against the Chicago Bears this Friday, the Eagles rank 21st in the league in rushing yards per game (110.5). Unless Barkley misses time with an injury, Bigsby can probably be left to the waiver wire in shallow fantasy formats.

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NFL Network's Tom Pelissero reports that the NFL will review San Francisco 49ers wide receiver Juan Jennings' actions on Monday night against the Carolina Panthers for a possible fine, but he won't be suspended. Panthers safety Tre'Von Moehrig took a cheap shot to a sensitive area for Jennings late in Monday night's game, and Jennings had to be held back following the conclusion of the contest. The 28-year-old caught five of his seven targets for 41 yards and his fourth touchdown of the season in the 20-9 victory. Three of Jennings' four scores on the year have come in the last four games, and he has a higher fantasy ceiling with quarterback Brock Purdy recovered from a turf-toe injury that caused him to miss most of the season. Going into a tough Week 13 matchup against the Cleveland Browns, Jennings should be viewed as a touchdown-dependent WR3/flex option.

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Los Angeles Rams running back Blake Corum was beginning to carve out some standalone fantasy value after three straight weeks with double-digit carries. However, his momentum has stalled in the last two weeks, as he's seen a combined 15 carries for 34 yards on the ground while catching just one pass for a loss of five yards. Despite the Rams blowing out the Tampa Bay Buccaneers on Sunday night, the 25-year-old had only seven carries for 24 yards and wasn't targeted in the passing game. Corum has had a bigger role behind Kyren Williams in 2025 in his second year in the league, but it has led to just 82 rushing attempts for 341 yards and one touchdown on the ground in 11 games. He's a fine handcuff for fantasy managers who have Williams rostered, but he won't be recommended as a flex play when the Rams face the Carolina Panthers in Week 13.

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Baltimore Ravens head coach John Harbaugh said that wide receiver Rashod Bateman (ankle) was a full participant in practice on Tuesday, according to Jeff Zrebiec of The Athletic. It puts Bateman on track to play on Thursday against the division-rival Cincinnati Bengals on Thanksgiving Day after he missed the last two games with an ankle sprain. The 25-year-old's return in Week 13 would make veteran DeAndre Hopkins less attractive as a flex play in deeper fantasy leagues in a great matchup against Cincy's soft pass defense. Bateman would be returning to an excellent matchup if he's active on Thursday, but he will still be hard to trust in a Ravens offense that has not been clicking. The Ravens have the fourth-fewest passing yards per game (176.6), and Bateman has not been trustworthy for fantasy managers with a 16-194-2 line in nine games. He's averaging a career-low 21.6 yards per game.

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The Indianapolis Colts announced on Tuesday that they placed wide receiver Ashton Dulin (hamstring) on Injured Reserve and signed safety George Odum to the active 53-man roster in a corresponding move. The team also signed cornerback Cameron Mitchell to their practice squad. Dulin will be forced to miss at least the next four games and will not be eligible to return until Week 17 against the division-rival Jacksonville Jaguars on Sunday, Dec. 28. The 28-year-old wideout has mostly been a factor on special teams for the first-place Colts. Dulin has caught only five passes for 106 yards on eight targets and has not scored a touchdown on offense through 10 games. For at least the next four weeks, Anthony Gould and Laquon Treadwell will have more opportunities in the WR4 role behind Michael Pittman Jr., Alec Pierce, and Josh Downs.

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Indianapolis Colts wide receiver Josh Downs caught just two of his six targets for 10 yards in Sunday's overtime loss to the Kansas City Chiefs in Week 12. Downs was trending up in fantasy football after recording touchdown grabs in three straight games, but the 24-year-old has had back-to-back duds with three total receptions (eight targets) for just 13 yards the last two games. He has taken a back seat in the Colts' passing game behind receiver Michael Pittman Jr. and rookie tight end Tyler Warren. While the former third-rounder is still useful depth in most fantasy formats, he'll be hard to trust going into a difficult Week 13 matchup against the league's top defense in the Houston Texans. Downs is up to 38 receptions for 326 yards and three touchdowns on 54 targets in 10 games in 2025 in his third year in the NFL.

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The Los Angeles Chargers opened rookie first-round running back Omarion Hampton's (ankle) 21-day practice window on Tuesday, according to Ari Meirov of The 33rd Team. The Chargers are coming out of their bye in Week 12, and Hampton is now eligible to return from Injured Reserve after missing the team's last six games with a left-ankle injury. Whether the 22-year-old is cleared to play this Sunday against the division-rival Las Vegas Raiders in Week 13 will depend on how much he's able to do in practice this week. The North Carolina product was operating as L.A.'s clear lead back before his ankle injury, thanks to Najee Harris' season-ending Achilles injury. Kimani Vidal has been the Bolts' RB1 with Hampton sidelined, but his fantasy stock will take a huge hit when Hampton returns. Hampton should not be floating around on any waiver wires in fantasy football leagues.

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When the Atlanta Falcons spent a first-round pick on quarterback Michael Penix Jr. (knee) in the 2024 NFL Draft, approximately six weeks after signing veteran Kirk Cousins to a four-year, $180 million contract, they signaled a commitment to getting the QB position right, even if the approach was untraditional. Less than two years later, Penix suffered a season-ending ACL tear, the third since his college days, and Cousins sits at 8-8 as the Falcons starter following a Week 12 win over the Saints in which he failed to top 200 passing yards for his third straight start. Neither Penix nor Cousins has looked like a long-term answer at the position, and with Penix's injury timeline now adding uncertainty to his status for the beginning of the 2026 season, Atlanta could once again need to address the quarterback room this offseason.

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Cincinnati Bengals tight end Mike Gesicki returned from a five-week absence to record season-highs in targets, receptions, and yards in a Week 12 loss to the Patriots. While his final stat line of four receptions for 35 yards was only good enough for TE16 on the week, it was clear early on Sunday that the Bengals had a plan to feature their athletic tight end in a game that All-Pro receiver Ja'Marr Chase missed due to suspension. Heading into a Week 13 Thanksgiving matchup with the Ravens, receiver Tee Higgins (concussion) has already been ruled out, giving Gesicki another opportunity for an increased workload. With quarterback Joe Burrow (toe) in line to return this week, it should also be noted that Gesicki's three redzone targets in Burrow's two starts this year are tied with Chase for the team lead. Gesicki is RotoBaller's TE19 this Week, but he offers enough upside to make him a matchup-dependent streaming candidate.

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Arizona Cardinals wide receiver Michael Wilson has seen a staggering 32 targets over his last two games, converting that into 25 catches for 303 yards. In a rare third-year midseason breakout, he has taken full advantage of the opportunity presented by the two-game absence of Marvin Harrison Jr. (appendix), who continues to recover from an emergency appendectomy. When asked on Tuesday about Wilson's role upon Harrison's return, Cardinals offensive coordinator Drew Petzing offered that he would be moved around the formation while continuing to see early reads. He went on to say, "When you produce in this league, we're gonna give you more opportunities to continue to do that." Wilson remains a must-start for as long as Harrison is out, but in a suddenly pass-heavy Jacoby Brissett-led offense, he should maintain flex value down the stretch and into the fantasy playoffs.

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Dallas Cowboys wide receiver George Pickens (knee/calf) will practice on Tuesday after being listed as a limited participant on Monday's estimated injury report. Pickens was banged up during the team's Week 12 win over the Eagles, spending a few snaps on the sideline, but he was able to return to action and ultimately ended the game with nine receptions for 146 yards and a touchdown. Pickens has been a fantasy MVP this season, currently the overall WR2, and he has recently put to rest any fears that the return of All-Pro CeeDee Lamb would eat into his ceiling potential. Playing in another island game on Thanksgiving, Pickens remains a strong WR1 play in Week 13, even against a stifling Kansas City defense.

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Baltimore Ravens quarterback Lamar Jackson (toe) returned to practice on Tuesday after missing Monday's walkthrough with a toe injury. With the Ravens facing a shortened week before a Thanksgiving matchup with the Bengals, this follows the same timeline Jackson has seen in each of the previous two weeks. Jackson has started the last four games after missing the previous three with an ankle injury, but he has finished as a QB1 in only one of those weeks, while finishing as QB29 and QB24 in his last two outings. Jackson represents a level of upside that's nearly impossible to keep on the bench, but it's clear he is currently hampered by injury, so fantasy managers should temper expectations in what would normally be a dream matchup against a porous Bengals defense.

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Dynasty | Vikings quarterback JJ McCarthy completed just 12-of-19 passes for 89 yards with no touchdowns and two interceptions against the Packers. Dynasty Analysis: Among the 813 quarterbacks who have attempted 150 passes in a season since 2005, McCarthy's completion percentage (54.1 percent) ranks 771st. His EPA per drop back ranks 807th out of 813. In short, he's been historically terrible for Minnesota. Even worse, this is a quarterback who essentially sat out a year to learn behind Sam Darnold. At this point, it's fair to wonder if Minnesota really does have their future quarterback on the roster. His ADP and ranking are free-falling with no bottom in sight.