Detroit Lions quarterback Jared Goff posted huge numbers in his team's Week 15 loss to the Los Angeles Rams, completing 25 of 41 pass attempts for 338 yards, three touchdowns, and zero interceptions. Across 14 games this season, the 31-year-old has now completed 69.3% of his pass attempts for 3,672 yards, 29 touchdowns, and five interceptions. With the Lions' defense struggling, Goff has been forced to turn to the air with regularity over the second half of the season. After attempting more than 30 passes in a game just once over the season's first seven weeks, Goff has topped that mark six times over his last seven games. Goff has thrown for at least 250 yards in all seven of those contests. As long as Detroit continues to find itself in pass-heavy game scripts, Goff could continue to have chances to rack up numbers. The Lions will host the Pittsburgh Steelers in Week 16.

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San Francisco 49ers quarterback Brock Purdy led his team to a 37-24 win over the Tennessee Titans in Week 15, completing 23 of 30 pass attempts for 295 yards, three touchdowns, and zero interceptions. Purdy also rushed for 44 yards on seven attempts. Across six games played this season, the 25-year-old has thrown for 1,442 passing yards, 12 touchdowns, and seven interceptions. Purdy has battled multiple injuries so far in 2025, but he seems to be hitting his stride down the stretch of the season. Purdy has completed at least 70% of his pass attempts in three out of his last four starts, leading San Francisco to a 4-0 record and an average of 31 points per game over that stretch. The 49ers will travel to Indianapolis to take on the Colts in Week 16.

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Buffalo Bills running back James Cook put up a dominant performance in his team's critical Week 15 win over its division rival, the New England Patriots, on Sunday. Cook recorded 22 carries for 107 yards and two touchdowns, and two receptions for four yards and a score. The 26-year-old has now racked up 1,686 yards from scrimmage and 12 touchdowns on 302 touches across 14 games this season. Cook has topped 100 scrimmage yards in five straight games and 11 out of 14 total contests in 2025. He also continues to dominate backfield touches in Buffalo, logging 22 of the team's 26 rushing attempts by running backs in Week 15. Cook profiles as a must-start fantasy running back heading into a Week 16 matchup against the Cleveland Browns.

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Jacksonville Jaguars running back Travis Etienne Jr. had a huge game in his team's 48-20 Week 15 win over the New York Jets on Sunday. Although the 26-year-old struggled to just 32 rushing yards on 12 carries, he more than made up for it by hauling in three receptions for 73 yards and three touchdowns on four targets. Etienne Jr. has now recorded 1,203 yards from scrimmage and 12 touchdowns on 242 touches across 14 games this season. He's established himself as the clear RB1 in a Jacksonville offense that is hitting its stride down the stretch of the season. Etienne Jr. remains a must-start fantasy running back heading into his Week 16 matchup against the Denver Broncos.

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Detroit Lions wide receiver Amon-Ra St. Brown had one of the most productive games of his career in his team's Week 15 loss to the Los Angeles Rams, recording 13 receptions for 164 yards and two touchdowns on 18 targets. The 26-year-old has now hauled in 94 catches for 1,140 yards and 11 touchdowns on 135 targets across 14 games this season. With tight end Sam LaPorta (back) on IR, the Lions' passing game is now highly concentrated around St. Brown, wide receiver Jameson Williams, and running back Jahmyr Gibbs. In Week 15, those three players earned 34 targets on 41 pass attempts from Lions quarterback Jared Goff. If Detroit's defense continues to struggle and consistently puts the team in pass-heavy game scripts, St. Brown could continue to see a high volume of targets down the stretch of the season. The Lions will host the Pittsburgh Steelers in Week 16.

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Green Bay Packers head coach Matt LaFleur said that wide receiver Christian Watson (chest) was taken to the hospital for further evaluation on his chest injury following his team's Week 15 loss to the Denver Broncos. Watson recorded three catches for 29 yards on five targets before being forced to exit the game in the third quarter. The 26-year-old missed Green Bay's first six games of the 2025 season while rehabbing a knee injury that ended his 2024 season. Watson has been coming on strong of late, recording five touchdown catches over his last four games coming into Week 15. While the exact severity of Watson's injury is unclear, his status would appear to be up in the air for Green Bay's Week 16 matchup against the Chicago Bears next Saturday night. If Watson is sidelined, Packers wideouts Romeo Doubs, Jayden Reed, Dontayvion Wicks, and Matthew Golden could all see increased roles.

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Dallas Cowboys running back Javonte Williams (shoulder) is questionable to return to his team's Week 15 matchup against the Minnesota Vikings due to a shoulder injury, per ESPN's Todd Archer. The 25-year-old recorded six carries for 13 yards and a touchdown before exiting the game. If Williams is unable to return, Malik Davis would be the only remaining running back on the Cowboys' active roster and would likely dominate backfield snaps for the remainder of Week 15. Fullback Hunter Luepke and wide receiver KaVontae Turpin could also handle some rushing work. Williams entered the week with 1,150 scrimmage yards and 11 touchdowns on 248 touches, so his absence would be a big loss for the Dallas offense.

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Los Angeles Rams wide receiver Davante Adams (hamstring) suffered a hamstring injury during the team's 41-34 win over the Detroit Lions on Sunday. Adams exited Sunday's game after reaggravating his left hamstring that he had been managing over the last couple of weeks. The 32-year-old had hauled in four catches for 71 yards on nine targets before exiting the game in the fourth quarter and did not return. Coach Sean McVay sounded pessimistic about Adams' status for Thursday's game against the Seattle Seahawks, then went on to say, "but I certainly wouldn't rule him out quite yet," reported by Stu Jackson of RamsNFL. It is worth noting that the Rams did clinch a playoff spot after their win over the Lions.

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Arizona Cardinals S Budda Baker and CB Garrett Williams each had eight total stops and five solo tackles in Week 15 against the Houston Texans. Williams was credited with a tackle for loss, too.

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Tennessee Titans wide receiver Van Jefferson exited the Titans' Week 15 matchup against the San Francisco 49ers in the second half due to a back injury. Jefferson hauled in one catch for 43 yards on five targets before leaving the game. The 29-year-old has shown flashes this season and has been a reliable target for rookie quarterback Cameron Ward at times during the year. The Titans have already battled injuries this season in their receiver room after losing Calvin Ridley for the season to a leg injury. Jefferson's status for their Week 16 matchup against the Kansas City Chiefs will be monitored as the team heads into the next week of practice.

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Washington Commanders RB Jeremy McNichols rushed nine times for six yards and caught one pass for 16 yards in a 29-21 win over the New York Giants in Week 15.

Fantasy Spin: Although McNichols saw 10 total touches, it was Jacory Croskey-Merritt who led the backfield with Chris Rodriguez Jr. sidelined. Even if Rodriguez misses more time, McNichols is unlikely to be a reliable option for fantasy owners.

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New Orleans Saints wide receiver Devaughn Vele (shoulder) exited during the fourth quarter of the team's 20-17 win over the Carolina Panthers. Vele left the game due to a shoulder injury after hauling in five catches for 69 yards on six targets. The 28-year-old was spotted after the game with his left arm in a sling, reported by Mike Triplett of NewOrleans.Football. With Vele in a sling, it will leave his availability in Week 16 against the New York Jets will be up in the air. Vele's status will become clearer when the Saints resume team practice on Wednesday.

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Washington Commanders QB Marcus Mariota completed 10 of his 19 passes for 211 yards and a touchdown and rushed 10 times for 43 yards and lost a fumble in a 29-21 win over the New York Giants in Week 15.

Fantasy Spin: Mariota was back under center in place of the injured Jayden Daniels, and while he only completed 10 passes, he was able to connect on some big plays against New York's struggling defense. He also topped 40 rushing yards for his third straight start, and if Daniels remains sidelined, Mariota can be a low-end QB2.

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Arizona Cardinals QB Jacoby Brissett completed 27-of-40 passes for 249 yards, three touchdowns and one interception in Week 15 against the Houston Texans.

Fantasy Spin: Brissett was facing a very difficult matchup against the suffocating Houston defense, but he had a decent statistical day, with most stats coming after the game was decided. Fantasy managers don't care how the points come, as long as they do. He has been putting up QB1-type fantasy numbers on a regular basis, shockingly.

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Updating a previous report, Washington Commanders WR Noah Brown (ribs) did not return to the Week 15 game against the New York Giants after suffering an injury to his ribs. The injury was initially reported as a back issue.

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According to Adam Schefter of ESPN, Green Bay Packers defensive lineman Micah Parsons (knee) is believed to have suffered a torn ACL and is expected to miss the remainder of the 2025 season and potentially a part of the 2026 season. Parsons sustained this non-contact injury during their Week 15 loss to the Broncos. The Packers acquired Parsons from the Cowboys in a blockbuster deal in the offseason and eventually signed him to a massive four-year $188 million contract. Before exiting Sunday's game, Parsons tallied two tackles with one sack. Through the first 14 weeks of the season, Parsons tallied 12.5 sacks with 39 total tackles. While sidelined, fantasy managers should expect Lukas Van Nes to see a larger role on the defensive line.

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Cleveland Browns rookie tight end Harold Fannin Jr. hauled in seven of his 14 targets for 48 yards during Sunday's 31-3 loss to the Chicago Bears. For the second straight week, Fannin led the team in receptions and targets, and he had one carry for two yards. The Cleveland offense struggled to gain its footing in Chicago, but the dependable rookie tight end continues to provide fantasy managers with a safe PPR floor. Fannin has a tough matchup against the Buffalo Bills' defense in Week 16, which has allowed the fewest points to tight ends this season. However, with David Njoku (knee) still dealing with an injury, Fannin is postured to remain a focal point and an offense that is engineering touches for him.

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According to the team, Kansas City Chiefs quarterback Patrick Mahomes (knee) has suffered a torn ACL. Mahomes exited Sunday's loss to the Chargers in the fourth quarter after suffering a left knee injury. Following the game, the three-time Super Bowl winner underwent an MRI, which eventually revealed the extent of their injury. The team noted that Mahomes and the club are currently exploring surgical options. As a result, this will keep the 30-year-old quarterback sidelined for the remainder of the 2025 campaign and potentially part of the 2026 season. Before exiting on Sunday, Mahomes went 16-for-28 with 189 yards, an interception, and added 15 yards and a score with his legs. For the remainder of the season, Gardner Minshew is slated to take over QB1 duties in Kansas City. He will carry mid-end QB2 upside in Week 16, facing a weak Tennessee secondary, playing in an offense with Rashee Rice, Xavier Worthy, and Travis Kelce.

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Los Angeles Rams wide receiver Puka Nacua (cramping) has returned to Sunday's contest against the Detroit Lions, according to Adam Schefter of ESPN. The star wideout exited the game in the fourth quarter due to a cramping injury. However, he was able to quickly return, suggesting this injury was not overly serious. Managers should keep an eye on his status during the week leading up to their Week 16 contest on Thursday evening in case he faces a setback. Nacua has enjoyed a stellar showing during this game, catching nine of his 11 targets for 181 yards, which is on track to be a season-high.

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Updating a previous report, Kansas City Chiefs QB Patrick Mahomes (knee) had an MRI which showed a torn anterior cruciate ligament in his left knee late in the Week 15 game against the Los Angeles Chargers. Mahomes and the team are exploring surgical options. QB Gardner Minshew is expected to take over the starting quarterback to finish the season.

Fantasy Spin: The news goes from bad to worse for the Chiefs, who were eliminated from the playoffs, and now this. The timetable for Mahomes' return is uncertain, but it's likely training camp and preseason will be unlikely, and the start of the 2026 season could also be in danger for Mahomes, since this injury occurred so late in the season.

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