Carolina Panthers wide receiver Hunter Renfrow has recorded 11 catches for 65 yards and two touchdowns on 19 targets through his first three games of 2025. Renfrow's target volume is impressive, but his 5.9-yard-per-reception average is less encouraging for his fantasy outlook heading into a Week 4 matchup against the New England Patriots. Still, the Panthers will be without wide receivers Xavier Legette (hamstring) and Jalen Coker (quad) as well as tight end Ja'Tavion Sanders (ankle) on Sunday. That leaves Renfrow as the likely number two option in the passing game for Panthers quarterback Bryce Young, behind rookie wideout Tetairoa McMillan. Despite that, Renfrow just doesn't have enough downfield juice to be counted on for consistent fantasy production. He should be avoided by fantasy managers in Week 4.

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Chicago Bears rookie tight end Colston Loveland (hip) is not expected to play in Week 4 against the Las Vegas Raiders due to a hip injury, according to ESPN's Adam Schefter. Loveland is off to a slow start to his NFL career, recording just three catches for 43 yards on six targets through three games. In his absence, veteran Bears tight end Cole Kmet could see more playing time in Week 4. Kmet has four catches for 70 yards and a touchdown on seven targets so far in 2025. He still profiles outside the fantasy top-12 at tight end, but Kmet could be a decent streaming option in Week 4.

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Green Bay Packers tight end Tucker Kraft has recorded 11 catches for 169 yards and two touchdowns on 15 targets through three games so far in 2025. The third-year tight end could be well set up for success in Week 4, as he'll face a Dallas Cowboys' defense that has been one of the worst in the NFL this season. Dallas ranks last in the NFL in yards allowed per pass attempt (9.8) and has allowed the second-most passing touchdowns in the league (seven). Kraft is currently the lead target-earner on the Packers. If Green Bay does have success through the air on Sunday, it could mean a huge game for Kraft. He profiles as a must-start fantasy tight end in Week 4 against the Cowboys.

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Houston Texans wide receiver Nico Collins (knee) missed time earlier in the week but did not get an injury designation for Sunday's matchup against the Titans. He was a limited participant on Wednesday but logged back-to-back full practices to finish the week. Despite the Titans struggling to score many points, Collins has found the end zone in each of the last two weeks, catching three of his nine targets for 52 yards and a score in Week 2 and following with his best game of the year, racking up eight catches for 104 yards and his second score of the season. While Nick Caley's offense hasn't been firing on all cylinders with QB C.J. Stroud at the helm, Collins has still been very involved and is a must-start WR1 now that he is healthy and ready to go against the Titans, who have allowed the fifth-most fantasy points to receivers this season. Collins is the WR5 in RotoBaller's rankings for Week 4, and he should be set up in a smash spot trying to get his Texans their first win of the season.

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New York Giants running back Devin Singletary has barely been utilized so far in 2025, recording just eight carries for 24 yards across three games. However, the Giants will be without running back Tyrone Tracy Jr. (shoulder) in Week 4 against the Los Angeles Chargers. That sets Singletary up to step into the RB2 role behind Giants rookie back Cam Skattebo. Skattebo has a three-down skill set, so fantasy managers should still expect Singletary's workload to be limited. Singletary is not worth starting in Week 4 against Los Angeles, but he could be worth rostering in deeper leagues as the handcuff to Skattebo while Tracy Jr. is sidelined.

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Dallas Cowboys wide receiver KaVontae Turpin has recorded 148 yards from scrimmage and a touchdown on 13 total touches through the first three weeks of 2025. With star wideout CeeDee Lamb (ankle) likely to miss Week 4 with a high ankle sprain, there could be even more of an emphasis for Dallas to manufacture touches for Turpin. The Cowboys have a difficult matchup on Sunday against the Green Bay Packers, who have given up an average of 14.7 points per game so far this season. That dims the outlook for Turpin, who will likely still finish behind wide receiver George Pickens, tight end Jake Ferguson, and running back Javonte Williams in total touches. At best, Turpin is a desperation flex option in deep leagues in Week 4 against Green Bay.

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Tampa Bay Buccaneers wide receiver Sterling Shepard has recorded 11 catches for 153 yards on 15 targets so far in 2025. The Buccaneers are expected to get wide receiver Chris Godwin (ankle) back on the field in Week 4, but the team will be without star wideout Mike Evans (hamstring) for multiple weeks. Godwin has not played since Week 7 of 2024 and may be on a limited snap count on Sunday, which could mean Shepard will see the second-most playing time at wide receiver behind rookie Emeka Egbuka. The Bucs have a difficult matchup in Week 4 against the Philadelphia Eagles, who have allowed just 5.9 yards per pass attempt and three passing touchdowns through three games. Shepard is difficult to trust as a fantasy starter. Still, he could be worth rostering in deep leagues until Godwin is fully integrated into the offense and Evans makes his return.

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Cincinnati Bengals kicker Evan McPherson hasn't missed this season. However, it's mostly due to a lack of opportunities, with the 26-year-old attempting only three kicks through the first three weeks of the 2025 campaign while draining all seven extra-point attempts. The Bengals offense has struggled so far this season. Many aren't optimistic that things will change on that side of the ball anytime soon, especially with Joe Burrow (foot) out for the foreseeable future. Until McPherson starts getting more chances to produce, he's not worth starting in all fantasy formats, including in Week 4 versus the Denver Broncos.

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Miami Dolphins head coach Mike McDaniel said tight end Darren Waller "looks firmly ready to contribute," according to Ian Rapoport of NFL Network. The veteran tight end came out of retirement to sign with Miami, which has treaded cautiously with him prior to making his team debut. Waller, now 33, hasn't played a game in two years after sitting out all of 2024, but looks set to play Monday against the New York Jets. On a Miami offense that has looked lost for most of this year, Waller has an opportunity for targets right away, but his biggest value will likely be in deeper leagues that start two tight ends.

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Cincinnati Bengals tight end Drew Sample has only three catches this season, with one resulting in a trip to the end zone. The 29-year-old has logged more snaps than Mike Gesicki and Noah Fant (foot) through the first three weeks of the 2025 campaign. However, both have received more attention from quarterbacks Joe Burrow (toe) and Jake Browning. The Bengals offense is a mess, which has been a surprise to most. As a result, it's hard to trust anyone on that side of the ball. Granted, Sample should continue to lead the position in snaps, especially with his abilities as a blocker. Still, while he will likely add a few more scores to his resume before the end of the season, he's not consistent enough to be considered a starting fantasy option in any format in Week 4 versus the Broncos.

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Cleveland Browns running back Dylan Sampson is likely headed for a role as the team's kick returner, according to Zac Jackson of The Athletic. The Browns rookie running back has seen his amount of offensive snaps decline each week after being a popular waiver-wire addition thanks to a whopping eight catches in Week 1. Since, he has only eight yards rushing and did not get a target in Week 3. Now that fellow rookie Quinshon Judkins is in the lineup, Sampson seems firmly in third in the pecking order behind Judkins and Jerome Ford. He's not a recommended starter in any format in Week 4 against Detroit.

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The Houston Texans are expecting clarity on running back Joe Mixon (foot/ankle) by mid-October, reports Dianna Russini of the Athletic. The veteran back hasn't seen the field at all in 2025 and remains on the Non-Football Injury list. Houston, meanwhile, signed running back Nick Chubb and drafted Woody Marks to man the backfield for the time being. Whether Mixon returns this year has been an open question for Houston, which is 0-3 and in need of all the offensive help it can get. If he returns, Mixon would be back for fantasy playoffs, but it seems like Houston's backfield will be a platoon even if he's healthy.

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Carolina Panthers running back Chuba Hubbard (calf) is expected to play Sunday against the New England Patriots, per David Newton of ESPN. Carolina's top back is officially listed as questionable, but it looks as if he'll be able to suit up come game time. Hubbard has been a solid fantasy performer despite playing on a struggling offense, ranking as the No. 12 overall running back in PPR formats. He's a solid RB2/Flex play against a so-so Patriots defense this week.

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Cincinnati Bengals wide receiver Tee Higgins struggled through the first three weeks. The wideout has been targeted 14 times, catching seven passes for 104 yards and a touchdown. To be fair, the entire offense hasn't looked the best. He's also at least stayed healthy, which is a plus. However, Higgins' lack of production has certainly been disappointing for fantasy managers. With the Bengals coming off an ugly 48-10 loss to the Minnesota Vikings in Week 3, the team will look to get it together on Monday night versus the Broncos. Without question, Higgins has plenty of talent. Unfortunately, until the offense can get on track, Higgins will be hard to trust. Despite the obvious upside, he's a risky fantasy option in any format in Week 4.

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Cincinnati Bengals quarterback Jake Browning will look to get the team back on track with a win over the Broncos on Monday night. With Joe Burrow (toe) out of the equation, Browning has gotten some action in the last two weeks. Unfortunately, the 29-year-old hasn't played well, combining for 381 yards, three touchdowns, and five interceptions off 40-for-59 passing. Granted, the offense wasn't operating the best even with Burrow under center. Still, Browning is hard to trust in Week 4 and beyond, and that won't change anytime soon until the offense can get on the same page. Keep the signal-caller out of all fantasy lineups.

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Cincinnati Bengals wide receiver Ja'Marr Chase was the No. 1 fantasy option for most entering the 2025 campaign. The former LSU Tiger is coming off a quality season, amassing 127 catches (175 targets) for 1,708 yards and 17 touchdowns. Unfortunately, things didn't go well through the first three weeks. Granted, Chase had 14 receptions for 165 yards and a touchdown in the Week 2 win over the Jaguars. However, he combined for seven grabs for 76 yards in Weeks 1 and 3. Joe Burrow (toe) won't be back on the field anytime soon, meaning the offense will operate with Jake Browning under center, at least for now. With that said, there's not a scenario where Chase shouldn't be starting in any fantasy format, although managers may continue to be disappointed until the offense can turn things around. In all fairness, he can't take all of the blame for his unproductive year so far. Still, this is the situation fantasy managers are faced with at the moment, so he's tough to trust in Week 4 versus the Denver Broncos.

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Carolina Panthers rookie wide receiver Tetairoa McMillan (calf) is "good to go" for his team's Week 4 matchup against the New England Patriots, according to ESPN's Jeremy Fowler. McMillan was limited all week in practice due to a calf injury and is officially listed as questionable on the injury report, but it appears he'll be able to suit up on Sunday. The Patriots are getting top cornerback Christian Gonzalez (hamstring) back from a hamstring injury, which could make life more difficult for McMillan. Still, McMillan has established himself as the top option for Panthers quarterback Bryce Young by recording 14 catches for 216 yards on 27 targets through his first three games of 2025. The 22-year-old rookie is a must-start fantasy wide receiver in Week 4 against New England.

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Dallas Cowboys wide receiver Jalen Tolbert has recorded six catches for 40 yards on 12 targets through three games this season. He should be in line for an increase in targets with star Cowboys wideout CeeDee Lamb (ankle) currently sidelined by a high ankle sprain. However, Tolbert will face a difficult matchup in Week 4 against the Green Bay Packers. Green Bay's defense has allowed the sixth-fewest passing yards (567) and fifth-fewest passing touchdowns (three) through the first three weeks of 2025. Tolbert could be the number two wide receiver in Dallas alongside George Pickens, but he'll likely be the number three target-earner at best behind Pickens and tight end Jake Ferguson. Tolbert could be a desperation flex option in deep leagues, but should be avoided by fantasy managers where possible in Week 4.

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Chicago Bears kicker Cairo Santos has had a quiet start to his 17th NFL season, making just two field goals and adding 10 extra points through three games. He currently ranks 29th in fantasy points among kickers, despite Chicago's offense performing well. Head coach Ben Johnson's aggressive approach (going for four fourth downs in field-goal range in the first three games) has limited Santos' opportunities. Week 4 brings a potential high-scoring matchup against the Las Vegas Raiders, which could lead to more attempts. Still, his lack of production early in 2025 makes him unstartable in most fantasy formats this week.

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Miami Dolphins wide receiver Tyreek Hill (personal) was not at practice on Saturday, but is expected to play in his team's Week matchup against the New York Jets on Monday night, according to Joe Schad of the Palm Beach Post. Hill has recorded 15 catches for 198 yards and a touchdown on 23 targets through his first three games of 2025. If Hill were to miss Week 4, Dolphins wide receiver Jaylen Waddle and running back De'Von Achane would likely see an uptick in targets. Assuming Hill is able to suit up, he profiles as a solid fantasy WR2 in Week 4 against the Jets.

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