Arizona Cardinals quarterback Kyler Murray (foot) is eligible to return from Injured Reserve as early as Week 14, and while the team prepares for a Week 13 matchup with the Buccaneers, he was spotted putting in work off to the side with some of the team's athletic trainers. Veteran Jacoby Brissett has been the team's starter since Week 6 and has reinvigorated Arizona's passing offense. Brissett has averaged 314.5 passing yards across his six starts, while throwing at least two touchdowns in five of six. Trey McBride is currently the top-scoring fantasy tight end in the league, and with Marvin Harrioson Jr. (appendix) missing the past two games following an emergency appendectomy, Brissett has transformed Michael Wilson and Greg Dortch into week winners. While the result in the win-loss column has not been as favorable, it seems unlikely that Murray will reclaim the starting job anytime soon, and it's still possible he's already taken his last snap with the team.

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Pittsburgh Steelers wide receiver DK Metcalf (ankle) will play this week against the Bills after an ankle injury caused him to miss Wednesday's practice. He returned to full participation by Thursday, and according to head coach Mike Tomlin, he will carry no injury designation into an AFC clash with notable playoff implications. Quarterback Aaron Rodgers (wrist) has also been cleared to play on Sunday, a week after Mason Rudolph was forced into a start against the Bears in which he threw for fewer than 175 yards on 5.5 yards per attempt. The connection between Rodgers and his top wide receiver has looked hit or miss throughout the year, but against an ailing Buffalo defense that has allowed 30+ points in two of its last three contests, Metcalf remains a viable WR2/Flex play and is RotoBaller's WR21 in a week with no teams on bye.

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Pittsburgh Steelers head coach Mike Tomlin said that quarterback Aaron Rodgers (wrist) won't have a game designation for this weekend and will play on Sunday against the Buffalo Bills in Week 13, according to Nick Farabaugh of Penn Live. Rodgers was a full participant in practice on Friday. "He just got more reps," Tomlin said. The head coach also said that Rodgers was able to take some snaps under center. The 41-year-old future Hall of Famer suffered a small fracture to his left (non-throwing) hand in Week 11 and did not play in last week's loss to the Chicago Bears. Rodgers has been a QB2 in fantasy in his first year in Pittsburgh, throwing for 1,969 yards, 19 touchdowns, and seven interceptions through 10 games played. Although he'll be facing a reeling Bills defense with plenty of injuries, Rodgers should remain in the low-end QB2 tier for fantasy purposes as he plays through his wrist fracture.

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Indianapolis Colts quarterback Daniel Jones (leg) was a full participant in practice again on Friday and will be ready to go on Sunday for a divisional clash against the Houston Texans in Week 13, according to Joel A. Erickson of the Indianapolis Star. "We would never put him out there if we thought something could go wrong," head coach Shane Steichen said. The 28-year-old Jones is working through a fractured fibula, but he has been practicing and will continue to play through the injury moving forward. Jones is a leading candidate for Comeback Player of the Year in the AFC in 2025, throwing for 2,840 yards, 17 touchdowns, and five interceptions through the first 12 weeks. His leg injury will be something to closely monitor, though, and fantasy managers should consider him a QB2 this weekend against the No. 1 defense in the NFL.

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Washington Commanders head coach Dan Quinn confirmed on Friday that wide receiver Terry McLaurin (quadriceps) will be active on Sunday night against the Denver Broncos in Week 13, according to Zach Selby of Commanders.com. "He's worked hard," Quinn said. McLaurin aggravated a quad injury in Week 8 and returned to practice for the first time this week, and now he's ready to return to action in a tough matchup against an elite Broncos defense that is expected to get All-Pro cornerback Patrick Surtain back. The 30-year-old veteran pass-catcher should operate as Washington's WR1 now that he's back, although it's possible he won't be on the field as much as he normally would if the Commanders decide to ease him back into the offense. Potentially on a snap count in a bad matchup, McLaurin is definitely one to fade in DFS this weekend.

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Washington Commanders wide receiver Noah Brown (groin, knee) has been ruled out for the Week 13 game against the visiting Denver Broncos on Sunday night in Week 13, according to head coach Dan Quinn. The Commanders opened Brown's 21-day practice window this week, but he will stay on Injured Reserve for another week. The 29-year-old's next chance to return will be for a Week 14 tilt against the Minnesota Vikings. The good news for the Commanders is that they will be getting Terry McLaurin (quadriceps) back for the first time since he aggravated his quad injury in Week 8. When Brown does return, he'll be battling for targets behind McLaurin and Deebo Samuel Sr. and won't be a must-roster player in 12-team fantasy football leagues. Brown has played in just two games in 2025 due to his injuries and has three receptions on seven targets for 36 scoreless yards.

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The Washington Commanders officially ruled out quarterback Jayden Daniels (elbow) for Sunday night's game against the visiting Denver Broncos in Week 13, according to Nicki Jhabvala of The Washington Post. Daniels has not played since suffering a gruesome dislocation of his left (non-throwing) elbow in the Week 9 loss to the Seattle Seahawks. The 24-year-old second-year signal-caller returned to practice for the first time this week, but he's not quite ready to make his return after several limited practices. Even though the Commanders are well out of playoff contention, they are optimistic that Daniels can return to play against the Minnesota Vikings in Week 14 if he's cleared for contact. For at least another week, veteran backup Marcus Mariota will lead Washington's offense this Sunday night against one of the best defenses in the league in the Broncos.

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Tampa Bay Buccaneers head coach Todd Bowles said that running back Bucky Irving (foot, shoulder) is in play to return on Sunday in Week 13 to face the Arizona Cardinals, according to Greg Auman of FOX Sports. Things were trending this way after Irving put in a full practice on Friday, but now it's official that Irving will be active in Week 13 for the first time since Week 4. The 23-year-old has recovered from a subluxation of his shoulder and a foot sprain. His fantasy managers will be happy to know he's back, but at the same time, he could easily disappoint in his first game after a long layoff, with the Bucs expected to put a limit on the number of snaps he plays on Sunday. Sean Tucker and Rachaad White should still be involved in Tampa's backfield against the Cards, making the Bucs' backfield a potential three-headed monster in Week 13.

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New York Giants interim head coach Mike Kafka confirmed on Friday that rookie quarterback Jaxson Dart (concussion) will start on Monday night versus the New England Patriots, according to Art Stapleton of The Bergen Record. Dart, who has missed the last two games due to a concussion, cleared the league's concussion protocol this week and will return to starting duties in Week 13, sending veteran Jameis Winston back to the bench after he nearly led the G-Men to an upset over the Detroit Lions last week. Despite a less-than-ideal matchup against the Patriots on Monday, the 22-year-old Dart should immediately be back in the QB1 conversation in fantasy football because of his dual-threat abilities. In the first seven starts of his career, Dart has been impressive with his arm and legs, throwing for 1,417 yards, 10 touchdowns, and three interceptions while adding 317 rushing yards and 7 TDs on the ground.

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Green Bay Packers defensive lineman Devonte Wyatt (ankle), who was carted off in the Thanksgiving Day win over the Detroit Lions on Thursday, suffered a fractured ankle, according to Ian Rapoport of NFL Network. Wyatt's season is expected to be over. The 27-year-old defensive tackle was carted off Ford Field in the fourth quarter and now won't be available the rest of the year. It's a notable loss for a strong Packers defense the rest of the way. The former first-rounder will finish his fourth year in the NFL with 27 tackles (15 solo), four sacks, six tackles for loss, seven QB hits, and two pass breakups in his 10 starts. Karl Brooks (ankle) is also dealing with an injury, so Nazir Stackhouse could see more playing time on the interior of Green Bay's defensive line going forward.

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Tampa Bay Buccaneers head coach Todd Bowles said that quarterback Baker Mayfield (shoulder) looked good in practice on Friday and is trending towards starting on Sunday against the visiting Arizona Cardinals in Week 13, per Rick Stroud of the Tampa Bay Times. Mayfield was a DNP in Wednesday's practice but returned to a limited practice on Thursday. The 30-year-old could be listed as questionable on the final Week 13 injury report if he's limited again on Friday, but signs are pointing toward him playing through a low-grade AC joint sprain to his left (non-throwing) shoulder this weekend. If Mayfield plays, he probably won't be 100% and could suffer an in-game setback, making him a more risky high-end QB2 option for fantasy managers in a good matchup against Arizona. If Mayfield doesn't play, veteran Teddy Bridgewater would get the nod under center.

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Dallas Cowboys cornerback Trevon Diggs (concussion, knee) is expected to return in Week 14 to face the Detroit Lions, according to The Athletic's Jon Machota. Owner Jerry Jones said on 105.3 The Fan on Friday that Diggs "will be on the field in Detroit (next Thursday), in my view, (barring a setback)." The 27-year-old defensive back has not played since Week 6 due to a concussion and a knee injury, but he should be back on the field next week at Ford Field. It will be a much-needed addition to Dallas' secondary after DaRon Bland injured his foot in the Thanksgiving Day win over the Kansas City Chiefs on Thursday. Diggs, a two-time Pro Bowler and former All-Pro, has 18 tackles (13 solo) in his six games played in 2025. Since his 11-interception season in 2021, Diggs has had only six picks in the last three-plus years.

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Buffalo Bills head coach Sean McDermott said that wide receiver Joshua Palmer (ankle) will be limited in practice on Friday and will be listed as questionable to play in the Week 13 contest on Sunday against the hosting Pittsburgh Steelers, according to The Buffalo News' Katherine Fitzgerald. Palmer missed Wednesday's practice but will close out the week with two limited sessions, leaving hope that he will be active this weekend. Curtis Samuel has already been ruled out for Buffalo, but even if Palmer is active on Sunday, which is likely, fantasy managers should have better flex options to choose from. The 26-year-old has yet to score a touchdown in 2025 in his first year in Buffalo, and he just has not seen enough volume to warrant a roster spot in most leagues. With Keon Coleman being a healthy scratch the last two games, Palmer has had just four catches on nine targets for 38 yards.

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Buffalo Bills head coach Sean McDermott said that wide receiver Curtis Samuel (elbow, knee) will not play on Sunday in Week 13 against the Pittsburgh Steelers, according to Maddy Glab of BuffaloBills.com. Samuel will miss a second straight game, and it's unclear if the 29-year-old will be able to return for a Week 14 contest against the Cincinnati Bengals. Samuel has not been on the fantasy radar at all in 2025, as he's caught only seven passes on nine targets for 81 yards and one touchdown on the year. He was unable to take advantage of second-year wideout Keon Coleman being benched for the last two games for disciplinary reasons. Samuel was off the fantasy radar in most leagues last year as well in Buffalo, as he had a weak 31-253-1 line in 14 regular-season games.

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Buffalo Bills head coach Sean McDermott said that tight end Dalton Kincaid (hamstring) will be limited in practice on Friday and will be questionable to play on Sunday against the Pittsburgh Steelers in Week 13, according to Katherine Fitzgerald of The Buffalo News. Kincaid, who last played in Week 10, did not practice on Wednesday, but he'll close out the week with two limited practices. The 26-year-old could be a game-time decision this weekend, which will make things a bit more difficult for fantasy managers trying to make lineup decisions, as the Bills and Steelers play in the later window on Sunday. Kincaid should be a top target for quarterback Josh Allen if he's active. If Kincaid misses a third straight game, Dawson Knox will have a bigger role again. Knox hasn't done much with Kincaid out the last two games, though, catching only four passes for 40 yards and no touchdowns on seven targets.

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Miami Dolphins head coach Mike McDaniel reports that tight end Darren Waller (pectoral) could return for Sunday's home clash with the New Orleans Saints. The veteran had his 21-day practice window opened earlier this week, suggesting that he's close to a return. Per McDaniel, he's optimistic about Waller's status for Week 13's game against the visiting Saints, though it's "all dependent on today's [Friday] practice." Barring any setbacks, it appears that the 33-year-old is trending toward being available. While it wouldn't be surprising to see Miami play it slow with his snap count following the layoff, fantasy managers will find it difficult to sit him if active, considering his touchdown upside.

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Tampa Bay Buccaneers quarterback Baker Mayfield (shoulder) was seen practicing on Friday, according to Rick Stroud of the Tampa Bay Times. Mayfield is dealing with a low-grade AC joint sprain to his left (non-throwing) shoulder. He did not practice on Wednesday but upgraded to a limited practice on Thursday. The 30-year-old will likely be listed as questionable for Week 13 against the visiting Arizona Cardinals if he's limited again on Friday, and his status for Sunday's contest could be a game-time decision. It makes Mayfield a pretty risky starting QB option in fantasy football this weekend, even in a good matchup. If Mayfield is not cleared to play against the Cardinals, veteran Teddy Bridgewater would make his first start of the 2025 season. Bridgewater would be a low-end QB2 streaming option for fantasy managers in superflex leagues.

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The Washington Commanders released wide receiver Robbie Chosen on Friday, according to Nicki Jhabvala of The Washington Post. The Commanders added Chosen to their practice squad in mid-November due to injuries to Terry McLaurin (quadriceps) and Treylon Burks (finger). McLaurin is set to return in Week 13 to face the Denver Broncos on Sunday night, though, and Noah Brown (groin, knee) could also be back from Injured Reserve this weekend, so the Commanders don't have the need for Chosen as WR depth anymore. The 32-year-old veteran appeared in only three games with Washington and caught five of his nine targets for 53 yards and no touchdowns. He will now go back onto the open market as he seeks to latch on with another team as WR depth for the rest of the 2025 season.

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According to head coach Jonathan Gannon, Arizona Cardinals running back Trey Benson (knee) will miss Sunday's outing with the hosting Tampa Bay Buccaneers. The Florida State alum returned to practice last week and worked in a limited capacity as he battles back from a lengthy absence due to a knee injury. Benson would start this week the same; however, he'd be downgraded to a DNP on Thursday, and will now miss his eighth consecutive contest. For what it's worth, Gannon noted that the 23-year-old won't be shut down long-term. With Emari Demercado (ankle) and Bam Knight (knee) also dealing with their own respective injuries, it could be Michael Carter and Jermar Jefferson manning the backfield against the Buccaneers. Jefferson has been active just once for the team and has yet to receive a touch in 2025.

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Arizona Cardinals wide receiver Greg Dortch could be in for a downtick in production this Sunday if teammate Marvin Harrison Jr. (appendix) returns to action. Dortch has been solid over Arizona's previous two contests, racking up six catches and a touchdown in each, with Harrison Jr. sidelined due to an appendectomy. For as serviceable as the former's been, his workload is set to taper off significantly upon Harrison Jr.'s return. Despite Arizona airing it out at a pace of 50 pass attempts per game over their last three, the presence of an emerging Michael Wilson and superstar tight end Trey McBride will make it too tricky for quarterback Jacoby Brissett to support four fantasy-worthy options. If Harrison Jr. sits another week, Dortch would be a nice PPR play against the hosting Buccaneers.

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