New York Giants wide receiver Wan'Dale Robinson has recorded 18 catches for 237 yards and a touchdown on 27 targets so far in 2025. With star Giants wideout Malik Nabers (knee) set to miss the rest of the season after tearing his ACL in Week 4, Robinson could see a significant uptick in targets going forward. In the two games that Nabers missed in 2024, Robinson recorded 11 catches for 86 yards and a touchdown on 20 targets. The 24-year-old has been far more efficient on a per-catch basis in 2025 than he was last season, so he could be well-positioned to do damage if his targets spike as expected. In all fantasy leagues where he's not already rostered, Robinson should be a priority waiver-wire addition ahead of the Giants Week 5 matchup against the New Orleans Saints.

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New York Giants wide receiver Jalin Hyatt has neither been targeted nor recorded a catch so far in 2025. However, he could be in line for more opportunities following the unfortunate news that star Giants wideout Malik Nabers (knee) will miss the remainder of the season with a torn ACL. In 35 career games with the Giants across two-plus seasons, Hyatt has recorded 31 catches for 435 yards on 59 targets. He will likely remain behind Darius Slayton and Wan'Dale Robinson on the Giants' wide receiver depth chart, but Hyatt could carve out a role as the team's WR3. Hyatt is not yet worth rostering in fantasy, but he's a player for managers to monitor in the coming weeks.

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Tampa Bay Buccaneers running back Bucky Irving (ankle/foot) is "still gathering medical opinions on what's being termed an ankle and/or foot injury," according to Mike Garafolo and Ian Rapoport of NFL Network. Garafolo notes that "no one has ruled Irving out" for the team's Week 5 game against the Seattle Seahawks, but Irving is "sore" and his status is "up in the air." The 23-year-old has recorded 430 yards from scrimmage and two touchdowns on 90 total touches through his first four games of 2025. If Irving were to miss time, veteran Buccaneers running back Rachaad White would likely see a significant workload increase. White has logged 142 yards from scrimmage and a touchdown on 31 total touches so far this season. Third-year running back Sean Tucker could see an increase in touches as well. Tucker has been efficient (career 5.0 yards per carry) in a limited sample over the course of his career. If Irving is facing an extended absence, Tucker would be worth a roster spot in deep fantasy leagues.

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The Arizona Cardinals "could turn to (running back) Michael Carter as their lead back" if running back Trey Benson (undisclosed) misses time, according to Theo Mackie of azcentral.com. Benson is currently considered day-to-day with an undisclosed injury. Carter played in his first game of 2025 in Week 4 against the Seattle Seahawks, recording one carry for one yard. Emari Demercado served as the team's RB2 behind Benson against Seattle, but he is considered a passing-downs specialist. Carter played in three games for the Cardinals in 2024, logging 35 carries for 131 yards and a touchdown. Pending further updates on Benson's status for Week 5, Carter could be a player to add in deeper leagues ahead of Arizona's Week 5 matchup against the Tennessee Titans.

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New Orleans Saints running back Alvin Kamara had another solid workload in Week 4 against the Bills, turning 19 touches into 72 yards. Over the last four seasons, Kamara has averaged 20.3 touches and 97.7 yards per game. So far in 2025, he is averaging 19.5 touches for only 76.3 yards. While the decline in production can be attributed to poor offensive line play and a struggling offense overall, fellow running back Kendre Miller had a strong outing in Buffalo with 11 carries for 65 yards and a touchdown. Kamara looks to be an RB2 with upside against the Giants, and is worth monitoring if Miller continues to eat away from his usual workhorse load.

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New Orleans Saints quarterback Spencer Rattler is now 0-10 as a starter after Sunday's loss to the Buffalo Bills, though his play has taken a clear step forward. Through four weeks, he's completed 67.1% of his passes for 191 yards per game with five touchdowns and just one interception. The concern remains his lack of downfield aggression, averaging only 5.2 yards per attempt, which ranks 30th in the league. Rattler enters a solid matchup as a QB2/Superflex option against a Giants team coming off an upset of the Chargers, but another loss could open the door for rookie quarterback Tyler Shough to get his shot.

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Indianapolis Colts wide receiver Michael Pittman Jr. has enjoyed a big bounce-back this season after struggling through his 2024 campaign. Pittman has now caught a touchdown in three of his four contests while drawing 29 targets over that span and leading the Colts' wide receivers with 234 receiving yards. Pittman should stay hot as he will host the Las Vegas Raiders in Week 5. Pittman has settled in as an every-week WR3 in fantasy and should be fired up across all leagues for his matchup against the Raiders.

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Indianapolis Colts tight end Tyler Warren has been an excellent addition to his team's offense in 2025. The rookie found the end zone for the first time in his young career on a two-yard run in the second quarter of a 27-20 loss to the Los Angeles Rams in Week 3. Warren is leading the Colts in receiving thus far, hauling in 19 passes for 263 yards through four games. He will remain a no-brainer TE1 in fantasy heading into a Week 5 home matchup against the Las Vegas Raiders.

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Indianapolis Colts running back DJ Giddens has been quiet so far in his rookie season. The rookie did not receive a touch nor draw a target while playing on just 7% of the snaps in a Week 4 loss to the Los Angeles Rams. That being said, fellow backfield mate Tyler Goodson injured his groin during the loss to the Rams and could be in line to miss some time. If that happens, Giddens would stand to benefit as the team's clear-cut RB2 and would gain some fantasy value as a handcuff to star running back Jonathan Taylor. Giddens sets up as a must-roster for those with Taylor on their fantasy squads heading into a Week 5 matchup against the Las Vegas Raiders.

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Cleveland Browns running back Dylan Sampson turned in a quiet outing in a Week 4 loss to the Detroit Lions. Sampson lost two yards on his one carry while failing to corral his lone target in the lopsided loss to the Lions. The rookie running back has barely played over the past two weeks, coinciding with Quinshon Judkins getting fully integrated into the team's offense and operating as the Browns' bellcow. Sampson still retains a small amount of fantasy value as a handcuff, but he should not be anywhere near fantasy lineups heading into a Week 5 matchup against the Minnesota Vikings in London.

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Cleveland Browns tight end Harold Fannin Jr. has cooled since a hot start to the season, having caught just five passes for 49 scoreless yards over his past two games. That being said, Fannin has remained a big part of the Cleveland offense, drawing 10 targets over that span. He might see a bump as the Browns are expected to turn to rookie Dillon Gabriel under center heading into a Week 5 matchup against the Minnesota Vikings in London. Fannin should remain rostered in all fantasy formats and is worth a look as a solid TE2 heading into Week 5.

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Cleveland Browns quarterback Shedeur Sanders has yet to take the field in a regular-season game. That being said, there have been rumors that the team is considering starting rookie Dillon Gabriel ahead of a Week 5 matchup against the Minnesota Vikings in London. If the Browns do end up making the change, it remains to be seen whether Sanders will remain the team's QB3 or if he will move up to QB2 ahead of Joe Flacco, who has struggled as Cleveland's starter this season. Either way, it would be a minor surprise if the Browns don't find a way to get Sanders on the field at some point this season, if for no other reason than to see what they have in the former Colorado Buffaloes star. Sanders should remain rostered in deep, two-quarterback dynasty formats.

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Kansas City Chiefs wide receiver Xavier Worthy returned in Week 4 and immediately made an impact against the Ravens, posting 121 scrimmage yards on seven touches in his first game back from a dislocated shoulder. While some were worried about a potential reinjury, Worthy said postgame that once he took his first hit, he knew he was "good to go." With Rashee Rice suspended, Worthy delivered the best production of any Chiefs receiver despite playing only 59% of the snaps. He now draws a Week 5 matchup on Monday night against the Jaguars, who have surrendered the 10th-most fantasy points to wideouts this season. While Kansas City is expected to ease him back into full usage, Worthy profiles as a high-risk, high-reward WR2 option for Week 5.

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Pittsburgh Steelers running back Jaylen Warren (knee) was a surprise inactive before Week 4's win over the Minnesota Vikings. In his absence, Kenneth Gainwell exploded for 134 total yards and two touchdowns. Though Gainwell's performance could earn him more volume in the coming weeks, Warren was very effective as a pass-catcher through his first three games with quarterback Aaron Rodgers and should reclaim RB1 duties when he returns. The utilization of Darnell Washington in Pittsburgh's offense seemed to open up running lanes last week, so fantasy managers should be optimistic about Warren's potential going forward. The 26-year-old will now have the bye in Week 5 to get healthy ahead of a divisional bout with the stingy Cleveland Browns defense.

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Tampa Bay Buccaneers running back Rachaad White could be in line for an expanded workload in Week 5 against the Seattle Seahawks. White has been efficient to start the 2025 season, totaling 142 yards on 32 touches, including the game-winning touchdown in Week 2 against Houston. His 4.7 yards per carry mark is a career high and currently ranks 18th in the NFL. With starter Bucky Irving dealing with an injury from the Week 4 loss to Philadelphia, White may be asked to step back into a featured role. If Irving sits, White projects as a strong RB2 option and is a must-own in all fantasy leagues.

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Minnesota Vikings running back Aaron Jones Sr. (hamstring) is targeting a return in Week 8. Jones suffered the injury late in Week 2's loss to the Falcons and was placed on injured reserve afterward. With the Vikings entering the bye in Week 6, that means Jones' next opportunity to return is in Week 8, where they face the Los Angeles Chargers on a Thursday Night. The veteran has a lengthy history of hamstring issues, and with Jordan Mason performing well during his absence, Jones may struggle to reclaim his early-season workload. Fantasy managers should prepare for a potential timeshare rather than a full return to feature-back duties.

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Buffalo Bills wide receiver Khalil Shakir has reestablished himself as the team's WR1. After a slow start, Shakir has hauled in all nine of his targets for 114 yards and two touchdowns over the past two weeks, ranking as the WR14 during that span. Despite rookie Keon Coleman's explosive Week 1 performance, Shakir has now surpassed him in nearly every statistical category. Shakir draws a favorable Week 5 matchup against the Patriots, who have allowed the 11th-most fantasy points to wideouts this season. While his usage in Joe Brady's offense remains limited, Shakir profiles as a low-end WR3 for the rest of the 2025 season.

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Houston Texans running back Joe Mixon (ankle) remains without a timetable for return after undergoing offseason surgery. He was placed on the NFI list before the season, and head coach DeMeco Ryans confirmed Monday that there are still no updates and Mixon is "nowhere close" to returning. In Mixon's absence, rookie Woody Marks has taken over the backfield, exploding for 21 touches, 119 scrimmage yards, and two touchdowns in Week 4's win over the Titans. Even if Mixon returns later this year, Houston's offensive struggles could limit the fantasy ceiling for a two-back system. Mixon should stay stashed on fantasy rosters, but expectations need to be tempered, as a repeat of his 2024 production is unlikely.

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Miami Dolphins wide receiver Tyreek Hill (knee) required only one surgery and is targeting a return before the 2026 season, according to his agent, Drew Rosenhaus. Hill suffered a gruesome knee dislocation in Week 4's win over the Jets and was immediately taken to the hospital. Rosenhaus noted that Hill avoided nerve damage, blood flow complications, and broken bones, which is a positive sign for his long-term recovery. Hill remains under contract with Miami through 2026, though trade speculation had surfaced earlier this season. With Hill sidelined, Jaylen Waddle and De'Von Achane become the clear focal points of the passing game, while Malik Washington should also see an increased role and fantasy boost.

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The Dallas Cowboys have signed veteran wide receiver Parris Campbell to their practice squad, according to NFL Network's Tom Pelissero. Campbell, a former second-round pick, has battled through multiple significant foot and knee injuries throughout his six-year career, limiting him to 1,117 receiving yards and six touchdowns across 49 games. The Cowboys are dealing with injuries at wide receiver, most notably losing CeeDee Lamb for the next few weeks and Jonathan Mingo, who was placed on injured reserve prior to the season. Campbell could be elevated from the practice squad as soon as this week, but with the Cowboys' deep receiver group, he carries little to no fantasy value at this time.

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