Kansas City Chiefs wide receiver Xavier Worthy (shoulder, ankle) is expected to play against the Jacksonville Jaguars in Week 5 despite being listed as questionable, according to Matt Verderame of Sports Illustrated. The Chiefs made a late adjustment to their injury report that called Worthy's status into doubt just 24 hours before kickoff, but Verderame has reassured fantasy managers that "the expectation is [Worthy] will be okay." Nevertheless, given the timing of Monday Night Football, managers might want to add someone like JuJu Smith-Schuster or Tyquan Thornton, who can be seamlessly inserted into lineups if Worthy suffers a setback and can't play against the Jaguars.

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Los Angeles Chargers running back Omarion Hampton (left ankle) exited during the third quarter of Sunday's Week 5 contest against the Washington Commanders. The rookie was listed as questionable to return, but he never ended up getting back into the game. He finished Week 5 with 12 carries for 44 rushing yards, as well as six catches for 26 receiving yards. The 22-year-old wasn't able to replicate his top-tier showings from the previous two weeks, but he still turned in a solid fantasy performance, largely thanks to his involvement in the passing game. Fantasy managers should monitor his practice participation throughout the week. If healthy, he'll rank as a low-end RB1 against the Miami Dolphins.

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Kansas City Chiefs wide receiver Xavier Worthy (shoulder, ankle) is questionable to play against the Jacksonville Jaguars on Monday Night Football in Week 5. Although Worthy did not initially carry an injury designation into the weekend, the Chiefs have revised their injury report and are listing him as questionable just 24 hours before kickoff. This is something that fantasy managers should monitor, though there might not be a whole lot that you can do about it. 24 teams have already played games, which means the majority of rostered players are locked in fantasy leagues, making it difficult to change your lineup or add any players. Managers heavily invested in Worthy's availability should see if they can add a receiver like JuJu Smith-Schuster or Tyquan Thornton before the final two games of Week 5 kick off, in case he ends up being inactive.

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New York Jets quarterback Justin Fields completed 32 of 46 pass attempts for 283 yards, two touchdowns, and zero interceptions during Sunday's Week 5 loss to the Dallas Cowboys. He took five sacks but also rushed for 26 yards. Although the Jets are 0-5 this season, Fields has been quite productive from a fantasy perspective. In the three games where he has been fully healthy, Fields is averaging 28.2 fantasy points. He has seven total touchdowns and zero interceptions this year, though he also has two lost fumbles to his name. We've known about his rushing ability for quite some time, but we're also starting to see flashes of what he can do throwing the football -- even if it comes in garbage time. The Ohio State product is a mid-to-low fantasy QB1 for Week 6 against a strong Denver Broncos defense.

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Arizona Cardinals tight end Tip Reiman (right leg) was carted to the locker room during the second half of Sunday's Week 5 contest against the Tennessee Titans. He suffered the injury after failing to haul in his first and only target of the game. Given the urgency of the Cardinals' medical personnel to get the cart on the field for Reiman, this could be a very serious injury, and it's likely one that will keep him sidelined for the remainder of the contest. He has merely occupied a depth role in Arizona this season, catching just three passes for 18 yards. Elijah Higgins will step up as the No. 2 tight end behind Trey McBride.

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Detroit Lions wide receiver Kalif Raymond (neck) exited during the first half of Sunday's Week 5 contest against the Cincinnati Bengals. Although he was initially listed as questionable to return, he has since been downgraded to out. Raymond finishes the game with a kick return and a punt return, but no offensive targets. Grant Stuard and Jacob Saylors should handle return duties for the duration of his absence.

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Dallas Cowboys quarterback Dak Prescott completed 18 of 29 pass attempts for 237 yards, four touchdowns, and zero interceptions during Sunday's Week 5 win over the New York Jets. He also rushed for 28 yards and only took one sack. After stringing together some modest performances near the start of the season, Prescott has come on exceptionally strong lately, racking up eight touchdowns and zero turnovers in his last two contests. He has been able to play at a top-tier level despite being without his top receiver, CeeDee Lamb (ankle). The 32-year-old remains a strong mid-range QB1 option heading into next week's clash with the Carolina Panthers.

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Dallas Cowboys running back Javonte Williams rushed for 135 yards and one touchdown on 16 carries during Sunday's Week 5 win over the New York Jets. He also caught a four-yard touchdown pass. Williams is enjoying a terrific career resurgence in Dallas, scoring six touchdowns through five games while averaging 20.7 fantasy points (PPR) per contest. He has ranked as a mid-range RB1 so far this season, and with a firm grasp on the lead-back role, he remains a must-start fantasy option going forward. Williams has been an enormous fantasy draft steal with league-winning potential as the Cowboys' offense plays quite well. He should continue to feast next week against the Carolina Panthers.

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Detroit Lions wide receiver Kalif Raymond (neck) exited during the first half of Sunday's Week 5 contest against the Cincinnati Bengals. He is officially questionable to return. At the time of his departure, he had two special teams returns but had not been targeted on offense. Grant Stuard and Jacob Saylors should handle return duties for the duration of Raymond's absence.

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Houston Texans quarterback C.J. Stroud completed 23 of 27 pass attempts for 244 yards, nine touchdowns, and zero interceptions during Sunday's Week 5 win over the Houston Texans. He also broke off a 30-yard rush and took two sacks. The former No. 2 pick showed flashes of his rookie self as the Texans took advantage of an injury-riddled Ravens defense. Stroud set his season high in completion rate, passing yards, and passing touchdowns along the way. This was a very soft matchup for the young quarterback, so Sunday's result doesn't necessarily mean he's back to being a high-end QB1 every week. However, at the very least, the big game should give him some confidence going forward and give the Texans something to build off of and learn from. Houston has a Week 6 bye, which means they'll have an extra week to figure out what went right as they develop their game plan for Week 7 against Seattle.

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Indianapolis Colts running back Jonathan Taylor rushed 17 times for 66 yards and three touchdowns during Sunday's Week 5 win over the Las Vegas Raiders. He also caught three of four targets for an additional 20 receiving yards. While Taylor merely had modest yardage efficiency, he made up for it with his nose for the end zone. Taylor has had two different three-touchdown games over the last three weeks, and he ranks as the overall RB2 in fantasy football this season. He is also the league's leading rusher and has seven touchdowns. He should be deployed as a high-end RB1 every week, including next week against the Arizona Cardinals.

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Las Vegas Raiders tight end Brock Bowers (knee) is day-to-day, according to head coach Pete Carroll. Bowers is dealing with a bone bruise and PCL injury, and while the team had hoped a few extra days of rest would help, that wasn't the case. Carroll noted that, as kickoff drew near, it became clear that Bowers wouldn't be able to play in Sunday's game. At the moment, it's uncertain whether the star tight end will be ready for Week 6 against the Tennessee Titans. While Las Vegas presumably won't rush him back, they'd like to get Bowers on the field sooner rather than later. The team is incredibly short-staffed at tight end with Bowers and Michael Mayer (concussion) out, which left them with Albert Okwuegbunam and Ian Thomas as their top tight ends this past Sunday against Indianapolis.

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Carolina Panthers running back Rico Dowdle carried the ball 23 times for 206 rushing yards and a rushing touchdown during Sunday's Week 5 win over the Miami Dolphins. He also caught three of four targets for an additional 28 receiving yards. Dowdle filled in for the injured Chuba Hubbard (calf) and turned in one of the best individual fantasy performances we've seen through five weeks this season. He proved to be a terrific waiver wire addition for many fantasy managers who inserted him into their lineups on Sunday. Even if Hubbard returns next week, Dowdle has done more than enough to carve out a significant role on offense. He's worth deploying as an RB3/flex with RB2 upside going forward, including next week in a revenge game against the Dallas Cowboys.

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New York Giants wide receiver Darius Slayton (hamstring) exited during the second half of Sunday's Week 5 contest against the New Orleans Saints. He is officially questionable to return. He struggled with drops when on the field, catching just three of six targets for 31 yards. The Giants continue to deal with wide receiver injuries, as they were already without Malik Nabers (knee), who is done for the year. Wan'Dale Robinson will remain New York's primary wide receiver while wide receiver Jalin Hyatt and tight ends Daniel Bellinger and Theo Johnson earn more targets from Jaxson Dart.

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Los Angeles Chargers tight end Will Dissly (knee) is inactive for Sunday's Week 5 contest against the Washington Commanders. He had been listed as questionable and seemed to be trending in the right direction after logging a full practice Friday, but in the end, the Chargers decided to make him inactive. Oronde Gadsden will operate as Los Angeles' primary tight end while Tyler Conklin fills a depth role.

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Philadelphia Eagles tight end Grant Calcaterra (oblique) exited during the first half of Sunday's Week 5 contest against the Denver Broncos. He was initially listed as questionable but has since been downgraded to out. At the time of his departure, he had two receptions for 18 yards. Kylen Granson will step up as the Eagles' No. 2 tight end behind Dallas Goedert.

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Arizona Cardinals wide receiver Greg Dortch (collarbone) and cornerback Will Johnson (groin) are active for Sunday's Week 5 contest against the Tennessee Titans. Both players had been listed as questionable after being limited in practice this past week. Dortch has been a contributor in all four games this year, catching a total of eight passes while returning nine kicks and six punts. He's off the fantasy radar but could eventually have streaming appeal if Marvin Harrison Jr. or Michael Wilson were to get injured. Meanwhile, Johnson is returning from a two-game absence. He last played in Week 2 when he logged a 62 percent snap share and made three tackles. He'll look to make an impact against a subpar Titans offense.

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Tennessee Titans wide receiver Calvin Ridley (knee, elbow) is officially active for his team's Week 5 matchup against the Arizona Cardinals. Ridley practiced just once this week but will give it a go on Sunday. The 30-year-old is off to a slow start to the 2025 season with 10 catches for 141 yards and zero touchdowns on 24 targets through four games. Ridley profiles as a low-end flex option in three-wide receiver leagues in Week 5 against Arizona.

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Philadelphia Eagles tight end Grant Calcaterra (oblique) is questionable to return to his team's Week 5 matchup against the Denver Broncos due to an oblique injury. Calcaterra recorded two catches for 18 yards on two targets before getting injured. If Calcaterra is unable to return, Eagles tight end Dallas Goedert could see an uptick in playing time for the remainder of Week 5.

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Indianapolis Colts kicker Spencer Shrader (knee) is doubtful to return to his team's Week 5 matchup against the Las Vegas Raiders due to a knee injury. Shrader was crashed into by a Raiders defender and left the field with a significant limp. Before getting injured, Shrader knocked in both of his extra-point tries, but did not attempt a field goal. If Shrader is unable to return, Indianapolis may have to turn to punter Rigoberto Sanchez to handle all of its kicking duties.

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