Indianapolis Colts quarterback Daniel Jones put together an unbelievable season debut on Sunday. He completed 22-of-29 passing attempts for 272 yards with one touchdown. Jones didn't stop there as he rushed seven times for 26 yards with an additional two scores. I don't think anyone had Jones scoring three touchdowns on their opening week bingo card. It will get more challenging for Jones in Week 2 against a tough Denver Broncos defense. After that, Jones will play the Titans, Rams, and Raiders. Fantasy managers shouldn't expect another three-touchdown game for Jones in Week 2. However, he could be an interesting long-term option given the Colts do play some lackluster defenses early in the season.

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Tennessee Titans running back Kalel Mullings (ankle) wasn't able to do much of the field during the season opener. He appeared in only a handful of snaps before exiting with an ankle injury. Now, Mullings is opening Week 2 on the sideline for Wednesday's practice. The absence of Mullings leaves Julius Chestnut as the lone backup behind Tony Pollard right now. Mullings will still have a few more days to practice before needing to make a final decision. The rookie back isn't someone that is going to offer much value right now, but is worth stashing in dynasty formats. Fantasy managers will need to check back throughout the week for another update on his status.

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Buffalo Bills wide receiver Keon Coleman (groin) logged a full practice session during Wednesday's practice. This is good news after Coleman was battling a groin injury throughout last week. The groin issue didn't stop him in the season opener as he recorded eight receptions for 112 yards and a touchdown in the win. The second-year wideout appears ready to take the next step this season. It appears Coleman and quarterback Josh Allen have improved chemistry from last season. It was only one game, but this could be a breakout year for Coleman. The 22-year-old should be started in most fantasy formats after that 112-yard season opener.

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Denver Broncos tight end Evan Engram (calf) was forced to make an early exit from Sunday's season opener against the Tennessee Titans. Engram was pulled out of the contest with a calf injury and didn't return. Now, Engram will open the week as a limited participant in practice on Wednesday. It doesn't sound like the injury is too serious, so the Broncos are probably just being extra cautious. Barring any setbacks, Engram should be out there versus the Indianapolis Colts in Week 2.

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San Francisco 49ers running back Christian McCaffrey (calf, rest) did not participate in practice on Wednesday. This shouldn't come as a surprise after McCaffrey dealt with a calf issue all throughout last week. It didn't stop him from playing as he rushed 22 times for 69 yards while hauling in nine receptions for an additional 73 yards in the season opener. He opens the practice week on the sideline, but that is probably for rest purposes. The 49ers want to give McCaffrey time to fully heal his calf issue. Fantasy managers should expect McCaffrey to be out there for Week 2. He'll remain an elite RB1 as long as he can stay healthy.

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Green Bay Packers kicker Brandon McManus looks to keep his solid run going in Week 2 as the Packers host the Washington Commanders on Thursday Night Football. McManus kicked two field goals from 38 and 34 yards out and converted all three of his extra point attempts in Week 1 as the Packers beat the Lions 27-19. In the regular season, McManus has missed just one kick in his Packers' career, so he's been reliable. Given that the Packers are on a trajectory to be one of the upper-echelon teams in the NFL, McManus should get plenty of opportunities in the future for Green Bay. He's startable in leagues with a kicker slot if you didn't get one of the top kickers in your draft.

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Los Angeles Rams OT Rob Havenstein (ankle), OG Kevin Dotson (ankle), OG Steve Avila (ankle), WR Davante Adams (rest) and TE Colby Parkinson (shoulder) did not practice Wednesday, Sept. 10. TE Davis Allen (knee) was a limited participant.

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Chicago Bears CB Kyler Gordon (hamstring) and DT Grady Jarrett (knee) did not participate in practice Wednesday, Sept. 10. LB T.J. Edwards (hamstring), CB Josh Blackwell (groin), RB Roschon Johnson (foot) and WR Jahdae Walker (ankle) were limited during practice. WR DJ Moore (abdomen, groin) and CB Jaylon Johnson (calf, groin) fully participated in practice. The Bears only held a walkthrough Wednesday, so the report is an estimation.

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Tennessee Titans S Quandre Diggs (hand), OT JC Latham (hip), RB Kalel Mullings (ankle) and DT T'Vondre Sweat (ankle) did not participate in practice Wednesday, Sept. 10. LB Arden Key (pectoral), CB L'Jarius Sneed (knee) and S Kevin Winston Jr. (hamstring) were limited during practice.

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Chicago Bears WR DJ Moore (abdomen, groin) fully participated in practice Wednesday, Sept. 10. The Bears only held a walkthrough Wednesday, so this is an estimation.

Fantasy Spin: Moore had a solid start to the season with 68 yards on three catches. He will be on of the main targets in the passing game this season and can be a No. 2 or No. 3 receiver in fantasy leagues.

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San Francisco 49ers DE Nick Bosa (non-injury), DE Yetur Gross-Matos (knee), WR Jauan Jennings (shoulder), RB Christian McCaffrey (calf), QB Brock Purdy (shoulder, toe) and OT Trent Williams (knee) did not participate in practice Wednesday, Sept. 10. OG Ben Bartch (elbow, knee), RB Jordan James (finger) and WR Jordan Watkins (ankle) were limited during practice. LB Luke Gifford (knee), QB Mac Jones (knee) and OG Dominick Puni (knee) fully participated in practice.

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Green Bay Packers wide receiver Matthew Golden (ankle) was a limited participant on Monday with an ankle injury, but put in two full practices to come off the injury report as the Packers host the Commanders in Week 2. Golden caught both of his targets for 16 yards on a day where the Packers' passing game wasn't too busy in their 27-13 victory over the Lions. Quarterback Jordan Love only needed 22 pass attempts to dispatch Detroit, and it was more of the same dating back to the post-bye Packers from 2024 as they opted to run the ball more than pass. The lack of passing volume from Green Bay hampers the upside of some of the passing game's weapons, like Golden. That said, Golden does have massive upside in this offense, and the Packers spent a first-round pick on his services, so Golden's offensive involvement will increase game by game. For fantasy, consider Golden an upside-laden flex play for Week 2.

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Green Bay Packers wide receiver Romeo Doubs led the Packers in receiving yards in Week 1 and looks to help pace the Packers' wide receivers again as Green Bay hosts the Washington Commanders in Week 2. Doubs led the Packers with 68 receiving yards on just two catches; one being a 48-yard snag in the second quarter as the first of a two-play drive that led to a Jayden Reed touchdown. Doubs led the wide receivers in routes as he was on the field for 71 percent of Jordan Love's dropbacks. Still, Doubs is simply a low-end fantasy flex play with his production that is very boom or bust and hard to prognosticate in a given week.

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Green Bay Packers tight end Tucker Kraft scored in Week 1 and looks to make it back-to-back scoring weeks as the Packers host the Washington Commanders in Week 2. Kraft scored on a 15-yard pass from quarterback Jordan Love to kick off the scoring for the Packers in Week 1. Other than that score, the 24-year-old only caught one more pass for one yard on an additional three targets. The Packers' pass-catchers are heavily reliant on touchdowns rather than target volume, but no pass-catcher saw the field and ran more routes than Kraft did with 92 percent route participation in Week 1. For Week 2 against the Commanders, Kraft is a decent TE1 fantasy play with the hopes that the Packers get pushed by the Commanders on the offensive end.

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San Francisco 49ers RB Christian McCaffrey (calf) did not participate in practice Wednesday, Sept. 10.

Fantasy Spin: McCaffrey had an outstanding Week 1 performance despite the injury and should be available this week even if he does not do much during practice. He will likely see a significant amount of touches with Brock Purdy injured and is a must-start option in all fantasy leagues.

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Green Bay Packers running back Chris Brooks looks to build on his minor role within the team's offense as the Packers host the Washington Commanders in Week 2. Brooks played well in Green Bay's preseason games, and his status in the running back pecking order ahead of fellow back Emanuel Wilson remained true. While Brooks remains a clear and distant role player for the Packers, he did get much more work than Wilson did. If something happened to Josh Jacobs, it's fair to say Brooks' role would increase in what would likely be a split backfield with Wilson. Brooks' situational role keeps him firmly on waivers for Week 2.

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Green Bay Packers wide receiver Jayden Reed (foot) did not practice on Monday but came off the injury report without a designation after two limited practices. He'll suit up for the Packers as they face the Washington Commanders on Thursday Night Football. Reed led Green Bay in targets with five and scored a touchdown on three catches for 45 yards. As a slot-only receiver, Reed rarely gets the chance to play on the outside in anything but 11 personnel. He's been a frustrating player to roster in fantasy since the second half of 2024, so that's why it's tough to trust Reed as anything more than a flex play despite an excellent matchup against the Commanders.

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Minnesota Vikings LB Blake Cashman (hamstring), RB Ty Chandler (knee), C Ryan Kelly (toe), TE Josh Oliver (ankle) and LB Andrew Van Ginkel (concussion) did not participate in practice Wednesday, Sept. 10. WR Myles Price (knee) and S Harrison Smith (illness) were limited during practice. OT Christian Darrisaw (knee), WR Jalen Nailor (hand), RB Zavier Scott (ankle) and DE Elijah Williams (hamstring) fully participated in practice.

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Green Bay Packers quarterback Jordan Love is a low-end quarterback streamer for Thursday Night's Week 2 matchup against the Washington Commanders. As fantasy football's QB17 in Week 1, Love only had 22 pass attempts during Green Bay's 27-13 win over the Detroit Lions. He didn't have to do a lot of heavy lifting, but still threw two touchdown passes while falling just short of 200 yards passing. After the Packers' Week 10 bye, Green Bay was a very run-focused team where Love played game manager, which wasn't great for fantasy. The Packers looked like a Super Bowl contender on the defensive side of the ball in Week 1, which doesn't bode well for fantasy production if opposing teams are not pushing them. Love can be treated as a QB2 in Superflex formats and a low-end streamer in single-quarterback leagues for Week 2.

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Green Bay Packers running back Josh Jacobs looks to build off a solid Week 1 performance in his Week 2 matchup at home against the Washington Commanders on Thursday Night. Jacobs scored a touchdown and took 19 totes for 66 yards on the ground with a catch for yards through the air. It was a typical line for Jacobs, who has been a touchdown-scoring machine for the Packers since last season's Week 10 bye, having scored at least one rushing touchdown in every game since. He's one of the most dependable fantasy running backs in the league with volume and production on what looks like one of the best teams in the NFL. Jacobs is an easy RB1 for Week 2's matchup with Washington, with his typical volume as he looks to make it 10 straight regular-season games with a rushing touchdown.

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