Guardians rookie Parker Messick carried a no-hit bid into the ninth inning before Leody Taveras led off with a single to begin a two-run rally, but Cleveland held on for a 4-2 victory over the visiting Baltimore Orioles on Thursday night.

Messick (3-0), making his 11th major league appearance, only permitted two baserunners in the first eight frames on walks to Taylor Ward in the first and Taveras in the sixth. The left-hander tied his career high with nine strikeouts and walked two.

Taveras hit a grounder to the left of second baseman Juan Brito, who dove but couldn't keep the ball in the infield. Blaze Alexander followed with a single, chasing Messick after eight-plus innings. Cade Smith gave up two hits and allowed two inherited runners to score, but was credited with his fourth save.

Jose Ramirez hit a two-run homer and George Valera and Steven Kwan had RBI hits for the Guardians, who snapped a two-game skid in the opener of the four-game series.

Tigers 10, Royals 9

Colt Keith's single capped a three-run, ninth-inning rally, allowing Detroit to stretch their winning streak to six games with a wild victory over visiting Kansas City.

Riley Greene's two-run, two-out double tied the contest for the Tigers. Greene then scored on Keith's single to right off Lucas Erceg (0-1). Greene had three hits and scored two runs, and Dillon Dingler had a two-run homer.

The Royals erased a five-run deficit with a six-run seventh, and Vinnie Pasquantino's solo homer made it 9-7 in the top of the ninth. Salvador Perez hit a three-run homer among four RBIs and Bobby Witt Jr. had three hits, scored three runs and drove in another.

Padres 5, Mariners 2

Fernando Tatis Jr. knocked in two runs and Walker Buehler pitched into the sixth inning for his first win with San Diego as the Padres stretched their winning streak to eight games with a victory over visiting Seattle.

Buehler (1-1) limited the Mariners to two runs on five hits in five-plus innings. Mason Miller logging his sixth save by striking out the side in the ninth as the Padres finished a 7-0 homestand.

Seattle starter Luis Castillo (0-1) gave up seven hits and four runs (one earned) over 5 1/3 innings. Cal Raleigh had two hits and an RBI.

Giants 3, Reds 0

Landen Roupp carried a no-hitter into the sixth inning, Jung Hoo Lee had three hits with an RBI and San Francisco snapped a four-game losing streak with a victory over host Cincinnati.

P.J. Higgins' sixth inning single off Roupp (3-1) proved to be the only hit of the game for Cincinnati. Erik Miller struck out the side in the ninth to pick up his first career save. San Francisco scored all of its runs in the seventh off hits from Matt Chapman, Lee and Casey Schmitt.

Cincinnati starter Chase Burns held the Giants to two hits over six shutout innings. Brock Burke (1-1) took the loss after allowing three unearned runs. Reds reliever Connor Phillips was ejected in the eighth inning for hitting Willy Adames in the thigh with a pitch. Benches cleared after a strikeout of Sal Stewart which ended the game got heated.

Angels 11, Yankees 4

Mike Trout homered for the fourth straight game to cap a monster series at Yankee Stadium and help Los Angeles pull away from New York.

Trout hit five homers in the four-game series, becoming the fourth player to hit five homers in a series against the Yankees. The others were Jimmie Foxx (1933), Darrell Evans (1985) and George Bell (1990). Jo Adell added his fourth career grand slam in the eighth and former Yankee Oswald Peraza homered in the first, giving the Angels an American League-leading 32 home runs.

Aaron Judge homered in the first inning and Giancarlo Stanton hit a two-run homer to center in the third to give the Yankees a 3-2 lead. Ben Rice also homered, but the Yankees lost for the seventh time in nine games.

Nationals 8, Pirates 7 (10 innings)

James Wood had two hits, including a two-out go-ahead RBI single in the 10th inning to lead Washington over host Pittsburgh.

Daylen Lile and Drew Millas also had two hits for the Nationals.

Jake Mangum led the Pirates with three of their 15 hits. Griffin, Oneil Cruz, Brandon Lowe and Nick Gonzales each had two hits and an RBI for the Pirates, who committed four errors.

Brewers 2, Blue Jays 1

A sacrifice bunt by Joey Ortiz scored Garrett Mitchell for the go-ahead run as host Milwaukee edged Toronto.

Milwaukee turned to small ball in the bottom of the seventh to claim the series win. Milwaukee used three straight bunts to take its first lead of the game. Mitchell led off the inning with a walk and a Greg Jones sacrifice bunt moved him to second base with one out.

David Hamilton laid down a bunt single and Milwaukee had runners on first and third. Ortiz's bunt only dribbled a few feet in front of home plate, but it was enough to score Mitchell for a 2-1 lead.

Rays 5, White Sox 3

Hunter Feduccia and Taylor Walls drew bases-loaded walks in the ninth inning after Junior Caminero hit a game-tying solo home run, propelling streaking Tampa Bay past host Chicago.

The Rays stretched their winning streak to six games, regrouping after Chicago's Everson Pereira smacked a solo shot in the eighth to give the White Sox the lead. Yandy Diaz, Richie Palacios, Nick Fortes and Caminero had two hits apiece for the Rays.

Chase Meidroth and Pereira both had two hits for the White Sox, who stranded seven runners compared to 14 for Tampa Bay.

Rangers 9, Athletics 6

Joc Pederson stroked the tiebreaking single in a four-run ninth inning as Texas notched a victory over the host Athletics in West Sacramento, Calif.

Josh Jung smacked a two-run homer among his three hits and Ezequiel Duran had two hits and two RBIs as the Rangers earned a split of the four-game series with their American League West rivals.

Nick Kurtz's three-run double in the bottom of the eighth gave the Athletics the lead. Jacob Wilson had a two-run single for the Athletics while Shea Langeliers reached base five times on two hits and three walks. Lawrence Butler, Carlos Cortes, Kurtz and Wilson also had two hits for the A's.

Rockies 3, Astros 2

Chase Dollander recorded a career-high nine strikeouts out of the bullpen while Hunter Goodman hit his third home run of the series as visiting Colorado salvaged the finale of a three-game interleague set against Houston.

Dollander (2-1) allowed one hit and walked two batters while working 5 1/3 scoreless innings. He averaged 99.4 mph on 29 four-seam fastballs and 98.8 mph on 19 sinkers. Victor Vodnik pitched a hitless ninth inning for his second save.

Yordan Alvarez and Loperfido spotted Houston a 2-0 lead with RBI singles in the first. The Rockies sliced that deficit in the third when they loaded the bases on three walks before Tyler Freeman grounded into a double play that scored Kyle Karros. Goodman led off the fourth with a game-tying shot to left-center. Freeman pushed the Rockies ahead to stay with his RBI single off Christian Roa (0-1) in the fifth.