

| Benched | QB | Caleb Williams CHI | Owner | Tue Nov 25 6:30am CT |
| Benched | WR | Josh Downs IND | Owner | Tue Nov 25 6:30am CT |
| Benched | TE | Kyle Pitts ATL | Owner | Tue Nov 25 6:30am CT |
| Started | QB | Jordan Love GB | Owner | Tue Nov 25 6:30am CT |
| Started | WR | Ja'Marr Chase CIN | Owner | Tue Nov 25 6:30am CT |
| Started | WR | Jaylen Waddle MIA | Owner | Tue Nov 25 6:30am CT |
| Benched | TE | Dallas Goedert PHI | Owner | Tue Nov 25 6:32am CT |
| Started | WR | Ladd McConkey LAC | Owner | Tue Nov 25 6:32am CT |
| Benched | WR | Kayshon Boutte NE | Owner | Thu Nov 27 10:26am CT |
| Started | WR | Romeo Doubs GB | Owner | Thu Nov 27 10:26am CT |
| Benched | RB | Sean Tucker TB | Owner | Tue Nov 25 9:57am CT |
| Benched | WR | Xavier Worthy KC | Owner | Tue Nov 25 9:57am CT |
| Started | RB | Emanuel Wilson GB | Owner | Tue Nov 25 9:57am CT |
| Started | WR | Kayshon Boutte NE | Owner | Tue Nov 25 9:57am CT |
| Benched | RB | Dylan Sampson CLE | Owner | Tue Nov 25 1:52pm CT |
| Benched | WR | Jayden Higgins HOU | Owner | Tue Nov 25 1:52pm CT |
| Benched | WR | Cedric Tillman CLE | Owner | Tue Nov 25 1:52pm CT |
| Benched | TE | Harold Fannin Jr. CLE | Owner | Tue Nov 25 1:52pm CT |
| Started | RB | Bucky Irving TB | Owner | Tue Nov 25 1:52pm CT |
| Started | WR | Marvin Harrison Jr. ARI | Owner | Tue Nov 25 1:52pm CT |
| Started | WR | Quentin Johnston LAC | Owner | Tue Nov 25 1:52pm CT |
| Started | WR | Terry McLaurin WAS | Owner | Tue Nov 25 1:52pm CT |
| Benched | D/ST | Tampa Bay Buccaneers TB | Owner | Tue Nov 25 5:56pm CT |
| Started | D/ST | Green Bay Packers GB | Owner | Tue Nov 25 5:56pm CT |
| Benched | WR | Mack Hollins NE | Owner | Tue Nov 25 10:34am CT |
| Benched | TE | Dalton Schultz HOU | Owner | Tue Nov 25 10:34am CT |
| Benched | D/ST | Green Bay Packers GB | Owner | Tue Nov 25 10:34am CT |
| Started | WR | Ricky Pearsall SF | Owner | Tue Nov 25 10:34am CT |
| Started | TE | Cade Otton TB | Owner | Tue Nov 25 10:34am CT |
| Started | D/ST | Tampa Bay Buccaneers TB | Owner | Tue Nov 25 10:34am CT |
| Benched | QB | Sam Darnold SEA | Owner | Tue Nov 25 6:54am CT |
| Started | WR | Courtland Sutton DEN | Owner | Tue Nov 25 6:54am CT |
| Started | WR | Troy Franklin DEN | Owner | Tue Nov 25 6:54am CT |
| Started | RB | RJ Harvey DEN | Owner | Tue Nov 25 6:54am CT |
| Started | QB | Bo Nix DEN | Owner | Tue Nov 25 6:54am CT |
| Benched | D/ST | Atlanta Falcons ATL | Owner | Tue Nov 25 6:54am CT |
| Benched | WR | Wan'Dale Robinson NYG | Owner | Tue Nov 25 6:54am CT |
| Benched | WR | Alec Pierce IND | Owner | Tue Nov 25 6:54am CT |
| Benched | RB | Tyrone Tracy Jr. NYG | Owner | Tue Nov 25 6:54am CT |
| Started | D/ST | Denver Broncos DEN | Owner | Tue Nov 25 6:54am CT |
| Benched | K | Indianapolis Colts IND | Owner | Tue Nov 25 11:26am CT |
| Started | K | Los Angeles Chargers LAC | Owner | Tue Nov 25 11:26am CT |
| Benched | RB | Chris Rodriguez Jr. WAS | Owner | Wed Nov 26 12:25am CT |
| Started | RB | Kenneth Walker III SEA | Owner | Wed Nov 26 12:25am CT |
| Benched | WR | Xavier Legette CAR | Owner | Tue Nov 25 11:28am CT |
| Started | WR | Deebo Samuel WAS | Owner | Tue Nov 25 11:28am CT |
| Benched | RB | Kenneth Walker III SEA | Owner | Tue Nov 25 11:28am CT |
| Started | RB | Chris Rodriguez Jr. WAS | Owner | Tue Nov 25 11:28am CT |
| Benched | WR | Michael Pittman Jr. IND | Owner | Fri Nov 28 11:35am CT |
| Started | WR | Rome Odunze CHI | Owner | Fri Nov 28 11:35am CT |
| Benched | RB | Ashton Jeanty LV | Owner | Thu Nov 27 2:29pm CT |
| Started | RB | Javonte Williams DAL | Owner | Thu Nov 27 2:29pm CT |
| Benched | RB | Javonte Williams DAL | Owner | Tue Nov 25 9:48am CT |
| Started | RB | Devon Achane MIA | Owner | Tue Nov 25 9:48am CT |
| Benched | QB | Brock Purdy SF | Owner | Wed Nov 26 9:28pm CT |
| Benched | RB | Alvin Kamara NO | Owner | Wed Nov 26 9:28pm CT |
| Started | QB | Joe Burrow CIN | Owner | Wed Nov 26 9:28pm CT |
| Started | RB | Devin Neal NO | Owner | Wed Nov 26 9:28pm CT |
| No starting lineup changes performed this week. |
| Benched | QB | Baker Mayfield TB | Owner | Tue Nov 25 2:26pm CT |
| Benched | WR | Tee Higgins CIN | Owner | Tue Nov 25 2:26pm CT |
| Started | QB | Justin Herbert LAC | Owner | Tue Nov 25 2:26pm CT |
| Started | TE | Jake Ferguson DAL | Owner | Tue Nov 25 2:26pm CT |