

| Add TB | WR | Quentin Johnston LAC | Owner | Thu Nov 27 9:36am CT |
| Drop TB | WR | Tez Johnson TB | Owner | Thu Nov 27 9:36am CT |
| Started | QB | Trevor Lawrence JAX | Owner | Thu Nov 27 9:36am CT |
| Benched | QB | Baker Mayfield TB | Owner | Thu Nov 27 9:36am CT |
| Drop TB | D/ST | Tampa Bay Buccaneers TB | Owner | Thu Nov 27 9:32am CT |
| Started | WR | Troy Franklin DEN | Owner | Thu Nov 27 9:32am CT |
| Started | RB | Josh Jacobs GB | Owner | Thu Nov 27 9:32am CT |
| Add TB | WR | Tez Johnson TB | Owner | Thu Nov 27 9:32am CT |
| Benched | WR | Tez Johnson TB | Owner | Thu Nov 27 9:32am CT |
| Benched | RB | Zonovan Knight ARI | Owner | Thu Nov 27 9:32am CT |
| Started | D/ST | Cleveland Browns CLE | Owner | Thu Nov 27 2:42pm CT |
| Benched | WR | Marquise Brown KC | Owner | Thu Nov 27 2:39pm CT |
| Benched | WR | Rashid Shaheed SEA | Owner | Thu Nov 27 2:39pm CT |
| Started | WR | Marvin Harrison Jr. ARI | Owner | Thu Nov 27 2:39pm CT |
| Started | WR | Deebo Samuel WAS | Owner | Thu Nov 27 2:39pm CT |
| Benched | QB | Sam Darnold SEA | Owner | Thu Nov 27 11:58am CT |
| Started | QB | Jared Goff DET | Owner | Thu Nov 27 11:58am CT |
| Started | D/ST | Carolina Panthers CAR | Owner | Thu Nov 27 11:58am CT |
| Benched | WR | Michael Pittman Jr. IND | Owner | Thu Nov 27 1:04pm CT |
| Started | WR | Courtland Sutton DEN | Owner | Thu Nov 27 1:04pm CT |
| Benched | WR | Stefon Diggs NE | Owner | Thu Nov 27 1:04pm CT |
| Started | WR | Jaylen Waddle MIA | Owner | Thu Nov 27 1:04pm CT |
| Started | D/ST | San Francisco 49ers SF | Owner | Thu Nov 27 1:03pm CT |
| Benched | D/ST | Houston Texans HOU | Owner | Tue Nov 25 6:08pm CT |
| Started | D/ST | New England Patriots NE | Owner | Tue Nov 25 6:08pm CT |
| Benched | QB | Lamar Jackson BAL | Owner | Thu Nov 27 9:16am CT |
| Started | TE | AJ Barner SEA | Owner | Thu Nov 27 9:16am CT |
| Started | WR | Jauan Jennings SF | Owner | Thu Nov 27 9:16am CT |
| Add TB | RB | Devon Achane MIA | Owner | Thu Nov 27 9:16am CT |
| Started | RB | Devon Achane MIA | Owner | Thu Nov 27 9:16am CT |
| Started | QB | Patrick Mahomes KC | Owner | Thu Nov 27 9:16am CT |
| Benched | D/ST | Baltimore Ravens BAL | Owner | Thu Nov 27 9:16am CT |
| Benched | TE | T.J. Hockenson MIN | Owner | Thu Nov 27 9:16am CT |
| Drop TB | WR | DeVonta Smith PHI | Owner | Thu Nov 27 9:16am CT |
| Benched | WR | Tee Higgins CIN | Owner | Thu Nov 27 9:16am CT |
| Benched | RB | Bhayshul Tuten JAX | Owner | Thu Nov 27 9:16am CT |
| Started | D/ST | Indianapolis Colts IND | Owner | Thu Nov 27 9:16am CT |
| Benched | WR | Josh Downs IND | Owner | Fri Nov 28 7:47am CT |
| Started | RB | Kyle Monangai CHI | Owner | Fri Nov 28 7:47am CT |
| Started | D/ST | Los Angeles Chargers LAC | Owner | Thu Nov 27 6:32pm CT |
| Drop TB | WR | Wan'Dale Robinson NYG | Owner | Thu Nov 27 11:52am CT |
| Started | WR | Wan'Dale Robinson NYG | Owner | Thu Nov 27 11:52am CT |
| Add TB | WR | Parker Washington JAX | Owner | Thu Nov 27 11:52am CT |
| Benched | WR | Parker Washington JAX | Owner | Thu Nov 27 11:52am CT |
| Drop TB | WR | Michael Wilson ARI | Owner | Thu Nov 27 1:32am CT |
| Started | WR | Michael Wilson ARI | Owner | Thu Nov 27 1:32am CT |
| Add TB | WR | Wan'Dale Robinson NYG | Owner | Thu Nov 27 1:32am CT |
| Benched | WR | Wan'Dale Robinson NYG | Owner | Thu Nov 27 1:32am CT |
| Started | WR | Ladd McConkey LAC | Owner | Thu Nov 27 1:31am CT |
| Started | RB | Chris Rodriguez Jr. WAS | Owner | Thu Nov 27 1:31am CT |
| Add TB | WR | Michael Wilson ARI | Owner | Thu Nov 27 1:31am CT |
| Benched | WR | Michael Wilson ARI | Owner | Thu Nov 27 1:31am CT |
| Benched | RB | Emanuel Wilson GB | Owner | Thu Nov 27 1:31am CT |
| Started | D/ST | Miami Dolphins MIA | Owner | Tue Nov 25 11:47pm CT |
| No starting lineup changes performed this week. |
| Add TB | WR | Darnell Mooney ATL | Owner | Wed Nov 26 10:15am CT |
| Drop TB | RB | David Montgomery DET | Owner | Wed Nov 26 10:15am CT |
| Started | K | Cameron Dicker LAC | Owner | Wed Nov 26 6:03am CT |
| Started | RB | Woody Marks HOU | Owner | Wed Nov 26 6:01am CT |
| Benched | WR | Andrei Iosivas CIN | Owner | Wed Nov 26 6:01am CT |
| Benched | RB | Woody Marks HOU | Owner | Wed Nov 26 6:00am CT |
| Started | RB | RJ Harvey DEN | Owner | Wed Nov 26 6:00am CT |
| Started | QB | Jaxson Dart NYG | Owner | Tue Nov 25 6:12am CT |
| Drop TB | RB | Woody Marks HOU | Owner | Tue Nov 25 6:10am CT |
| Started | RB | Woody Marks HOU | Owner | Tue Nov 25 6:10am CT |
| Add TB | RB | David Montgomery DET | Owner | Tue Nov 25 6:10am CT |
| Benched | RB | David Montgomery DET | Owner | Tue Nov 25 6:10am CT |
| Add TB | RB | Woody Marks HOU | Owner | Tue Nov 25 6:09am CT |
| Benched | WR | Jordan Addison MIN | Owner | Tue Nov 25 6:09am CT |
| Benched | D/ST | Philadelphia Eagles PHI | Owner | Tue Nov 25 6:09am CT |
| Drop TB | RB | Zach Charbonnet SEA | Owner | Tue Nov 25 6:09am CT |
| Started | RB | David Montgomery DET | Owner | Tue Nov 25 6:09am CT |
| Started | WR | Ja'Marr Chase CIN | Owner | Tue Nov 25 6:09am CT |
| Started | D/ST | Denver Broncos DEN | Owner | Tue Nov 25 6:09am CT |
| Benched | RB | Woody Marks HOU | Owner | Tue Nov 25 6:09am CT |
| Benched | QB | Caleb Williams CHI | Owner | Thu Nov 27 6:43am CT |
| Benched | WR | Alec Pierce IND | Owner | Thu Nov 27 6:43am CT |
| Started | QB | Bo Nix DEN | Owner | Thu Nov 27 6:43am CT |
| Started | RB | Bucky Irving TB | Owner | Thu Nov 27 6:43am CT |
| Started | K | Chris Boswell PIT | Owner | Thu Nov 27 12:45pm CT |
| Benched | RB | Kenneth Walker III SEA | Owner | Thu Nov 27 12:42pm CT |
| Benched | WR | Tre Tucker LV | Owner | Thu Nov 27 12:42pm CT |
| Started | RB | Sean Tucker TB | Owner | Thu Nov 27 12:42pm CT |
| Started | WR | Jayden Higgins HOU | Owner | Thu Nov 27 12:42pm CT |
| Benched | QB | Matthew Stafford LAR | Owner | Thu Nov 27 9:11am CT |
| Benched | RB | Quinshon Judkins CLE | Owner | Thu Nov 27 9:11am CT |
| Add TB | RB | Quinshon Judkins CLE | Owner | Thu Nov 27 9:11am CT |
| Started | QB | Dak Prescott DAL | Owner | Thu Nov 27 9:11am CT |
| Started | WR | Christian Watson GB | Owner | Thu Nov 27 9:11am CT |
| Drop TB | WR | Christian Watson GB | Owner | Thu Nov 27 9:11am CT |